BioPortfolio - JUND - jun D proto-oncogene

JUND

Symbol:

JUND

Name(s):

jun D proto-oncogene

Type:

protein-coding

Organism:

Homo sapiens

Synonyms:

AP-1

Links:

Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link

Summary of findings

17495958

Coordinated down- and up-regulation of the various AP-1 subunits in the course of epidermal wound healing is important for its undisturbed progress, putatively by influencing inflammation and cell-cell communication.

18095154

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)

18078517

evidence is provided that HBZ/JunD heterodimers interact with Sp1 transcription factors and that activation of hTERT transcription by these heterodimers is mediated through binding sites for Sp1 present in the hTERT promoter.

17681951

Dimerization with the Jun proteins inhibits c-Fos nuclear exit.

17651017

Our data suggest that JUND and CLDN4 are critical mediators of the antiproliferative and antiviral effects of type I IFNs and further confirm the functional importance of the DNA-binding domain of Stat2.

16129800

JunD limits cardiomyocyte hypertrophy and protects the pressure-overloaded heart from cardiac apoptosis

12054733

JunD activated by LHRH acts as a modulator of cell proliferation and cooperates with the anti-apoptotic and anti-mitogenic functions of LHRH.

11903046

An alternative model of H ferritin promoter transactivation by c-Jun

16007120

JunD is another ARE regulatory protein for transcriptional activation of the human ferritin H gene and probably other antioxidant genes containing the conserved ARE sequences by which JunD may confer cytoprotection during oxidative stress

12082101

junD activation by ultraviolet rays plays a role in apoptosis in myeloblastic leukemia ML-1 cells

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