|
| |
JUP
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18245958 |
Overexpression of gamma-catenin caused an increase in PTTG and c-Myc protein levels, which are likely to accelerate chromosomal instability and uncontrolled proliferation, respectively, in the affected cells. |
| 17924338 |
A dominant mutation in the gene encoding plakoglobin in a German family with Arrhythmogenic right ventricular cardiomyopathy but no cutaneous abnormalities, is reported. |
| 12068170 |
stimulation of beta-catenin and suppression of gamma-catenin expression, occur within endometrial carcinomas with squamous differentiation |
| 14739224 |
show that the AML-associated translocation products (AATPs) directly activate the gamma-catenin promoter, which plays a crucial role in increasing the self-renewal of HSCs upon expression of AATPs |
| 14661054 |
plakoglobin can activate the Wnt signaling cascade directly without interaction of beta-catenin, and that plakoglobin has multiple functions as a transcriptional activator and a cell adhesion molecule like beta-catenin |
| 14661058 |
plakoglobin is a new target gene governed by HDAC, and it acts as an oncogene in HT1080 cells |
| 12386812 |
function as an inhibitor of beta-catenin/TCF-dependent gene transcription and role as a potentially novel tumor suppressor protein in a subset of human NSCLC cancers |
| 15701841 |
Methylation of the gamma-catenin gene is associated with renal cell carcinoma |
| 15781623 |
The gamma-catenin mutation related to Bcl-2 overexpression has a significant effect on the pathogenesis of hormone refractory prostate cancer. |
| 11984022 |
Arrhythmogenic right ventricular cardiomyopathy caused by a deletion in plakoglobin (Naxos disease). Review. | →View more information from publications. |
Recent Publications on JUP: |  |
Subcellular localization of desmosomal components is different between desmoglein3 knockout mice and pemphigus vulgaris model mice.
BACKGROUND: The desmoglein 3 (Dsg3) knockout mouse and pemphigus vulgaris... | 29th October, 2009
| Department of Dermatology, Saitama Municipal Hospital, 2460 Mimuro,
| J Dermatol Sci. 2009 Aug;55(2):108-15. Epub 2009 Jun 13.
DOI Direct Link |
Cardiomyopathies: New test for arrhythmogenic right ventricular cardiomyopathy.
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is... | 9th September, 2009
|
| Nat Rev Cardiol. 2009 Jul;6(7):450-1.
DOI Direct Link |
Exclusion of EGFR, HRAS, DSP, JUP, CTNNB1, PLEC1, and EPPK1 as functional candidate genes in 7 families with syndromic diarrhoea.
Syndromic diarrhoea (SD) is a rare disease associating intractable... | 29th July, 2009
| Service de Pediatrie Multidisciplinaire, Hopital d'enfants de la Timone,
| J Pediatr Gastroenterol Nutr. 2009 Apr;48(4):501-3.
DOI Direct Link |
Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy.
The phenotypic hallmark of arrhythmogenic right ventricular... | 29th May, 2009
| Center for Cardiovascular Genetics, Brown Foundation Institute of
| Circ Res. 2009 May 8;104(9):1076-84. Epub 2009 Apr 9.
DOI Direct Link |
Tetraspanin gene expression levels as potential biomarkers for malignancy of gingival squamous cell carcinoma.
Accurate assessment of malignancy in oral squamous cell carcinoma is... | 23rd May, 2009
| Division of Oral and Maxillofacial Surgery, Niigata University Graduate
| Int J Cancer. 2009 Jun 15;124(12):2911-6.
DOI Direct Link |
→View more research publications. |
JUP results (if any) from reagent suppliers | 
|
MUC1 antibody, MUC1 [B415 (VU13F11)] antibody Antibody, Mouse ...
Interacts with CTNNB1/beta-catenin and JUP/gamma-catenin and promotes cell adhesion. Interaction with JUP/gamma-catenin is induced by heregulin. ...
http://www.genwaybio.com/product_info.php?products_id=192917...
|
 |
γ-catenin (K-20) Antibody sc-30997
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, JUP, 3728, 17q21.2, NM_002230, ...
http://www.scbt.com/datasheet-30997-gamma-catenin-k-20-antib...
|
 |
E Cadherin antibody, E Cadherin [DECMA-1] Antibody, Rat Monoclonal ...
Interacts directly, via the cytoplasmic domain, with CTNNB1 or JUP to form the PSEN1/cadherin/catenin adhesion complex which connects to the actin skeleton ...
http://www.genwaybio.com/product_info.php?products_id=190575...
|
 |
PhosphoSignature™
JUP. Junction plakoglobin (Desmoplakin-3) ...... JUP. OCLN ezrin. CDLN3. CTNNB. DLG3. Iressa adhesion cytoskeletal reorganization survival proliferation ...
http://www.cellsignal.com/technologies/phosphoscan/pdfs/PSig...
|
 |
Search Bioportfolio and other Life Science Sites for JUP,
or search for JUP on BioPortfolio's antibody search engine.
This page has been viewed 475 times
Recent Search Terms used to find this page: gene name plakoglobin | junction plakoglobin | plakoglobin gamma catenin 2009 | gamma catenin wnt naxos | junction plakoglobin | h ju p | h ju p | jup junction | junction plakoglobin | .
Resources from the NCBI used on this page, NCBI's standard disclaimer applies.
|
