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AREG
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18045238 |
amphiregulin-specific EGF-R fate results from decreased hSprouty2 degradation and reduced Cbl recruitment to underphosphorylated EGF-R, two effects that impair EGF-R trafficking to lysosomes |
| 17942395 |
After exposure to cisplatin, the resistant breast cancer cells secrete amphiregulin protein by short interfering RNA resulting in a nearly complete reversion of the resistant phenotype. |
| 17962208 |
AREG is preferentially expressed in breast tumors co-expressing HER2/HER4. AREG is associated with estradiol receptors, small tumour size, low histoprognostic grading, high HER4 levels. |
| 17525275 |
AREG is up-regulated in tumor cells of SCC but not BCC of the skin. AREG is also overexpressed in asymptomatic epidermis adjacent to both SCC and BCC, relative to normal skin. |
| 16470170 |
Amphiregulin and HB-EGF mediate retinoic acid-mediated epidermal hyperplasia |
| 16336275 |
HAT induces amphiregulin production through the PAR-2 mediated ERK pathway, and then causes amphiregulin release by a TACE-dependent mechanism |
| 15696081 |
Amphiregulin was secreted by human mast cells after aggregation of FcepsilonRI. Amphiregulin may be new target molecule for treatment of overproduction of sputum in bronchial asthma. |
| 15696083 |
Mast cells secreted amphiregulin on IgE cross-linking, and amphiregulin induced proliferation of lung fibroblasts. Local release of amphiregulin by mast cells could play role in lung fibrosis by promoting proliferation of lung fibroblasts. |
| 16888076 |
findings demonstrated that PGE2 may mimic LH action at least in part by the activation of amphiregulin and epiregulin biosynthesis in human granulosa cells |
| 12356750 |
H358 cells secrete a high level of amphiregulin that, in combination with IGF1, prevents serum deprivation apoptosis | →View more information from publications. |
Recent Publications on AREG: |  |
Amphiregulin Promotes Resistance to Gefitinib in NonSmall Cell Lung Cancer Cells by Regulating Ku70 Acetylation.
Multiple molecular resistance mechanisms reduce the efficiency of receptor... | 15th October, 2009
| [1] INSERM, U823, Institut Albert Bonniot, Grenoble, France [2] Universite
| Mol Ther. 2009 Oct 13.
DOI Direct Link |
Amphiregulin Promotes BAX Inhibition and Resistance to Gefitinib in Non-small-cell Lung Cancers.
Molecular resistance mechanisms affecting the efficiency of receptor... | 15th October, 2009
| [1] INSERM, U823, Institut Albert Bonniot, Grenoble, France [2] Universite
| Mol Ther. 2009 Oct 13.
DOI Direct Link |
Reconstitution of amphiregulin-epidermal growth factor receptor signaling in lung squamous cell carcinomas activates PTHrP gene expression and contributes to cancer-mediated diseases of the bone.
Parathyroid hormone-related protein (PTHrP) is the causative factor of the... | 15th October, 2009
| Medical Sciences, Indiana University, Jordan Hall, Bloomington, IN 47405,
| Mol Cancer Res. 2009 Oct;7(10):1714-28. Epub 2009 Oct 13.
DOI Direct Link |
The arf-inducing transcription factor Dmp1 encodes a transcriptional activator of amphiregulin, thrombospondin-1, JunB and Egr1.
Dmp1 (Dmtf1) encodes a Myb-like transcription factor implicated in tumor... | 10th October, 2009
| The Departments of Pathology, Wake Forest University Health Sciences,
| Int J Cancer. 2009 Oct 8.
DOI Direct Link |
Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab.
PURPOSE: To study the power of the epidermal growth factor receptor (EGFR)... | 10th September, 2009
| Department of Pathology, Digestive Oncology Unit, University Hospital
| J Clin Oncol. 2009 Oct 20;27(30):5068-74. Epub 2009 Sep 8.
DOI Direct Link |
→View more research publications. |
AREG results (if any) from reagent suppliers | 
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AREG Antibody (C-term)
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with the AREG antibody (C-term) (Cat.#AP7776b), which was peroxidase-conjugated to
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http://www.abgent.com/products/catalog_no/AP7776b_AREG_Antib...
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Amphiregulin (C-13) Antibody sc-5796
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, AREG, 374, 4q13.3, NM_001657 ...
http://www.scbt.com/datasheet-5796-amphiregulin-c-13-antibod...
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Abgent - Cell and Function Antibodies
AT1175aNEW, ARD1 monoclonal antibody (M01), ELISA,IF,S-ELISA,WB-Ce, H. AP7776b NEW, AREG Antibody (C-term), IHC, E, H. AP6600cNEW, ARF3 Antibody (Center D93)
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http://www.abgent.com/products/category/cell_function...
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Tyrosine Kinases
AREG. Cytoskeletal. Regulation. Cell Motility. Tumor. Invasion. Increase. Cell Motility. Invasion. Metastasis. Proliferation. Apoptosis. Survival ...
http://www.cellsignal.com/about/marketing/pdfs/tyrosine_1008...
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Amphiregulin siRNA (m) sc-39413
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Areg, 11839, 5 E1, P31955 ...
http://www.scbt.com/datasheet-39413-amphiregulin-sirna-m.htm...
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IgY Antibodies - GenWay Biotech Inc.
AREG; AR; SDGF; CRDGF; MGC13647 - AR; Colorectum cell-derived growth factor; CRDGF; Amphiregulin preproprotein, IgY Polyclonal WB, Source: Chicken ...
http://www.genwaybio.com/all_igy_antibodies.php...
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