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KCNC4


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Symbol:KCNC4
Name(s):potassium voltage-gated channel, Shaw-related subfamily, member 4
Type:protein-coding
Organism:Homo sapiens
Synonyms:HKSHIIIC, KSHIIIC, KV3.4, MGC126818
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15485486 Kv3.4 was overexpressed in early stages of Alzheimer disease and in advanced stages was present at high levels in neurodegenerative structures. This subunit regulates delayed-rectifier currents, primary determinants of spike repolarization in neurones
16449802 The characterization of a missense mutation in MiRP2 that affects its phosphorylation and consequent interactions with Kv3.4 is reported.

Recent Publications on KCNC4:

Pubmed Logo
Gene expression profiling of human cardiac potassium and sodium channels.
BACKGROUND: The native cardiac ion currents and the action potential...
4th January, 2007
Department of Biology, Faculty of Medicine, University of Szeged, Somogyi Int J Cardiol. 2006 Aug 28;111(3):386-93. Epub 2005 Oct 27.
DOI Direct Link
Properties and expression of Kv3 channels in cerebellar Purkinje cells.
In cerebellar Purkinje cells, Kv3 potassium channels are indispensable for...
9th December, 2006
Rita Levi Montalcini Center for Brain Repair, Department of Neuroscience, Mol Cell Neurosci. 2006 Oct;33(2):170-9. Epub 2006 Sep 1.
DOI Direct Link
Bone morphogenetic protein-2 upregulates expression and function of voltage-gated K+ channels in human pulmonary artery smooth muscle cells.
Activity of voltage-gated K(+) (K(V)) channels in pulmonary artery smooth...
9th December, 2006
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Am J Physiol Lung Cell Mol Physiol. 2006 Nov;291(5):L993-1004. Epub 2006
DOI Direct Link
Phosphorylation and protonation of neighboring MiRP2 sites: function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis.
MinK-related peptide 2 (MiRP2) and Kv3.4 subunits assemble in skeletal...
16th March, 2006
Greenberg Division of Cardiology, Department of Medicine and Department of FASEB J. 2006 Feb;20(2):293-301.
DOI Direct Link
Potassium channels and proliferation of vascular smooth muscle cells.
MinK-related peptide 2 (MiRP2) and Kv3.4 subunits assemble in skeletal...
29th December, 2005
Circ Res. 2005 Dec 9;97(12):1211-2.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7611850 Ion channel assay methods
6969449 Multi-well plate and electrode assemblies for ion channel assays
7176016 High throughput method and system for screening candidate compounds for activity against target ion channels
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7276206 Electrical field stimulation of eukaryotic cells

View more patents.

KCNC4 results (if any) from reagent suppliers

Google CSE Logo
KCNC Antibody / KCNC Antibodies
KCNC4 (K-14) Antibody, sc-104343, goat IgG, Cytoplasmic (h), WB, IF, ELISA, m, r , h. KCNC4 (S-15) Antibody, sc-104344, goat IgG, Cytoplasmic (h), WB, IF, ...
http://www.scbt.com/table-kcnc.html...

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KCNC4 antibodies: Neuroscience > Neurotransmission > Receptors ...
KCNC4 antibodies. ... Image Abreview Publication. ab66638 · KCNC4 antibody. IHC- P, WB, IHC-Fr. Rabbit polyclonal. Reacts with: Hu. Predicted: Ms, Rat ...
http://www.abcam.com/index.html?t=253562&pt=1&c=392&ei=&mu=r...

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KCNC4 siRNA (r) sc-156044
Click here for details. suitable control antibody: KCNC4 (S-15): sc-104344; sqRT -PCR Primer also available: KCNC4 (r)-PR: sc-156044-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-156044-kcnc4-sirna-r.html...

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Complete Solutions for Ion Channels
KCNC4, NM_145922, potassium voltage-gated channel: Shaw-related subfamily: member 4, P9982. KCND2, NM_019697, potassium voltage-gated channel: Shal-related
...
http://www.sigmaaldrich.com/life-science/functional-genomics...

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KCNC4 siRNA (h) sc-88479
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: KCNC4 ...
http://www.scbt.com/ja/datasheet-88479-kcnc4-sirna-h.html...

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Abcam antibodies and reagents product map
... Insulin degrading enzyme / IDE antibodies (10) · Insulin degrading enzyme / IDE proteins and peptides (5) · KCNC4 antibodies (2) · KCNE3 antibodies (1) ...
http://www.abcam.com/index.html?cl=248&pageconfig=productmap...

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KCNC4 (K-14) Antibody sc-104343
KCNC4 (K-14) 抗体sc-104343 KCNC4 (K-14) Antibody sc-104343.
http://www.scbt.com/zh/datasheet-104343-kcnc4-k-14-antibody....

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