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KCND2
| Symbol: | KCND2 | | Name(s): | potassium voltage-gated channel, Shal-related subfamily, member 2 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | KIAA1044, KV4.2, MGC119702, MGC119703, RK5 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15563876 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 17981906 |
Our results further suggest distinct mechanisms for Kv4.2 gating modulation by KChIPs and DPPs. |
| 14559911 |
PSD-95 increased the amount of Kv1.4, but not Kv4.2, in lipid rafts. |
| 14623880 |
Kv4.2 and K+ channel-interacting protein 2 make up a complex of Ito channels |
| 15563876 |
mutations in KCND2 and KCND3 are not a frequent cause of long QT syndrome |
| 15358149 |
Data show that KChIP1, KChIP2.1, and KChIP2.2 could form homo- as well as hetero-oligomers, and that this oligomerization did not perturb their interaction with Kv4.2 potassium channel. |
| 16934482 |
Electrophysiological analysis indicates attenuated K+ current density in cells expressing this Kv4.2-N587fsX1 mutant channel, which is consistent with a model of aberrant neuronal excitability characteristic of TLE. |
| 16260497 |
Traffic of Kv4.2 is coat protein complex I (COPI)-dependent. |
| 16820361 |
the C-terminal domain of Kv4.2 plays a critical role in voltage-dependent activation and functional expression that is mediated by direct interaction between the Kv4.2 C terminus and KChIP2 |
| 17102134 |
two Ca2+-dependent posttranslational events regulate the activity of DREAM on Kv4.2 channel function | →View more information from publications. |
Recent Publications on KCND2: |  |
[Genetics components in patients with temporal lobe epilepsy.]
INTRODUCTION. Epilepsy is one of the major neurological disorders... | 28th October, 2009
| Hospital Universitario de la Princesa, 28006 Madrid, Espana.
| Rev Neurol. 2009 Nov 16-30;49(10):541-6.
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Identification of susceptibility loci at 7q31 and 9p13 for bipolar disorder in an isolated population.
We performed a linkage analysis on 23 Finnish families with bipolar... | 24th October, 2009
| FIMM, Institute for Molecular Medicine and National Institute for Health
| Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 22.
DOI Direct Link |
Proteomic analyses of native brain K(V)4.2 channel complexes.
Somatodendritic A-type (I(A)) voltage-gated K(+) (K(V)) channels are key... | 29th August, 2009
| Department of Developmental Biology, Washington University, St. Louis, MO,
| Channels (Austin). 2009 Jul-Aug;3(4):284-94. Epub 2009 Jul 16.
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Divergent regulation of cardiac KCND3 potassium channel expression by the thyroid hormone receptors alpha1 and beta1.
The cardiac transient outward current I(to) is regulated by thyroid... | 12th May, 2009
| Department of Internal Medicine III, University of Cologne, Kerpener Str.
| J Physiol. 2009 Mar 15;587(Pt 6):1319-29. Epub 2009 Jan 26.
DOI Direct Link |
Altered gene expression may underlie prolonged duration of the QT interval and ventricular action potential in streptozotocin-induced diabetic rat heart.
Ventricular electrical conduction has been investigated in the... | 10th March, 2009
| Department of Physiology, UAE University, Al Ain, UAE.
| Mol Cell Biochem. 2009 Aug;328(1-2):57-65. Epub 2009 Mar 8.
DOI Direct Link |
→View more research publications. |
KCND2 results (if any) from reagent suppliers | 
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Anti-Potassium Channel Kv4.2 (Shal1; RK5; Kcnd2) antibody produced ...
(Shal1, RK5, Kcnd2). Developed in Rabbit,. Affinity Isolated Antibody. Product Number P 0233. Product Description. Anti-Potassium Channel Kv4.2 is developed
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http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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KV4.2 (N-15) Antibody sc-11680
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, KCND2, 3751, 7q31.31, NM_012281 ...
http://www.scbt.com/ko/datasheet-11680-kv4-2-n-15-antibody.h...
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Complete Solutions for Ion Channels
KCND2, NM_019697, potassium voltage-gated channel: Shal-related subfamily: member 2, P0233. KCND3, NM_004980, potassium voltage-gated channel: Shal-related
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http://www.sigmaaldrich.com/life-science/functional-genomics...
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KV Antibody / KV Antibodies
製品名, カタログ番号, アイソタイプ, エピトープ, アプリケーション, 動物種. KVβ.1 (C-13) 抗体, sc-51104, goat IgG, C-terminus (h), WB, IF, ELISA, m, r, h, cow ...
http://www.scbt.com/ja/table-kv.html...
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Antibodies to Ion Channels
Anti-Potassium Channel Kv4.2 (Shal1; RK5; Kcnd2), rabbit, P0233. Anti-Potassium Channel Kv4.3, rabbit, P0358. Anti-Potassium Channel ROMK1, rabbit, P0856 ...
http://www.sigmaaldrich.com/life-science/cell-biology/antibo...
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KV4.2 (C-20) Antibody sc-11683
种属, 基因名称, 基因ID, 染色质位置, 亚型（mRNA）即位号码, 蛋白质即位号码, OMIM™ 号码. 人类, KCND2, 3751, 7q31.31, NM_012281 · Q9NZV8 ...
http://www.scbt.com/zh/datasheet-11683-kv4-2-c-20-antibody.h...
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KV4.2 (C-20) Antibody sc-11683
Species, Nome del gene, Codice del gene, Locus cromosoma, Isoform (mRNA) Accession #, codice accesso proteina, Numero d' ordine. Human, KCND2, 3751, 7q31
.31 ...
http://www.scbt.com/it/datasheet-11683-kv4-2-c-20-antibody.h...
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