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Fmr1
| Symbol: | Fmr1 | | Name(s): | Fmr1 | | Type: | protein-coding | | Organism: | Drosophila melanogaster | | Synonyms: | AT24755, BcDNA:GM08679, CG6203, EP(3)3517, FMRP, FXR, dFMR, dFMR1, dFMRP, dFXR, dFXR1, dmfr1, fmr | | Links: |
Pubmed,
Entrez Gene,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17519221 |
the first evidence that FMRP might be involved in the regulation of adult stem cells. |
| 17989302 |
Both FMRP and metabotropic glutamate receptor GluRA differentially regulate the abundance of different GluR subclasses in a convergent mechanism within individual postsynaptic domains. |
| 17194772 |
Substitution of critical isoleucines in the KH domains of Drosophila fragile X protein results in partial loss-of-function phenotypes. |
| 15737929 |
DFMR1 functions as a negative regulator in the orb autoregulatory circuit, downregulating orb mRNA translation. |
| 15964283 |
regulation of the actin cytoskeleton is under FMRP1 control. FMRP1 binds the mRNA of the Drosophila profilin and negatively regulates Profilin protein expression |
| 15634690 |
dFMRP normally down-regulates the monoamine pathway, which is consequently up-regulated in the mutant condition |
| 15183715 |
dFXR regulates microtubule stability in both synaptogenesis in the nervous system and spermatogenesis in the testes. |
| 17110444 |
in cleavage-stage Drosophila embryos, fragile X mental retardation protein affects protein expression by controlling the availability and/or competency of specific transcripts to be translated |
| 12460546 |
dFMR1 is subjected to transcriptional and posttranscriptional regulation during development, it homomerizes, and its expression recapitulates that of the human FXR protein family: it is enriched in muscles, in central nervous system and in gonads |
| 12368260 |
Fragile X-related protein and VIG associate with the RNA interference machinery | →View more information from publications. |
Fmr1 results (if any) from reagent suppliers | 
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