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KCNJ1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17401586 |
A novel mutation in KCNJ1 in a Bartter syndrome case diagnosed as pseudohypoaldosteronism. |
| 16428287 |
ROMK is antagonistically regulated by long and kidney-specific WNK1 isoforms |
| 15987778 |
NH(2)-terminal phosphorylation modifying a COOH-terminal ER retention signal in ROMK1 could serve as a checkpoint for proper subunit folding critical to channel gating. |
| 15895241 |
Findings support the proposed role of ROMK channels in potassium recycling and in the regulation of K+ secretion and present a rationale for the phenotype observed in patients with ROMK deficiency. |
| 12381810 |
One disease-causing mutation in the ROMK channel truncates the extreme COOH-terminus and induces a closed gating conformation. |
| 12589089 |
In a heterozgous Bartter syndrome patient, AA exchanges Arg338Stop & Met357Thr in ROMK exon 5 alter the C-terminus of the ROMK protein & can affect channel function. |
| 17380208 |
molecular mechanism for stimulation of endocytosis of ROMK1 by WNK kinases |
| 12221079 |
ROMK1 is a substrate of PKC and that serine residues 4 and 201 are the two main PKC phosphorylation sites that are essential for the expression of ROMK1 in the cell surface |
Recent Publications on KCNJ1: |  |
Re: research in areas of transport physiology.
Cells in taste buds are closely packed, with little extracellular space.... | 29th October, 2009
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| Am J Physiol Renal Physiol. 2009 Oct;297(4):F837. Epub 2009 Aug 19.
DOI Direct Link |
An intersubunit salt bridge near the selectivity filter stabilizes the active state of Kir1.1.
ROMK (Kir1.1) potassium channels are closed by internal acidification with... | 29th October, 2009
| Department of Physiology and Biophysics, The Chicago Medical School,
| Biophys J. 2009 Aug 19;97(4):1058-66.
DOI Direct Link |
A comprehensive guide to the ROMK potassium channel: form and function in health and disease.
The discovery of the renal outer medullary K+ channel (ROMK, K(ir)1.1),... | 29th October, 2009
| Dept. of Physiology, Univ. of Maryland School of Medicine, 655 W.
| Am J Physiol Renal Physiol. 2009 Oct;297(4):F849-63. Epub 2009 May 20.
DOI Direct Link |
Inward rectifier channel, ROMK, is localized to the apical tips of glial-like cells in mouse taste buds.
Cells in taste buds are closely packed, with little extracellular space.... | 5th September, 2009
| Department of Physiology & Biophysics, University of Miami Miller School
| J Comp Neurol. 2009 Nov 10;517(2):spc1.
DOI Direct Link |
Inward rectifier channel, ROMK, is localized to the apical tips of glial-like cells in mouse taste buds.
Cells in taste buds are closely packed, with little extracellular space.... | 27th August, 2009
| Department of Physiology & Biophysics, University of Miami Miller School
| J Comp Neurol. 2009 Nov 1;517(1):1-14.
DOI Direct Link |
→View more research publications. |
KCNJ1 results (if any) from reagent suppliers | 
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KCNJ1 antibodies: Signal Transduction > Metabolism > Plasma ...
KCNJ1 antibodies. ... KCNJ1 antibody - Cytoplasmic domain. IHC-P, WB, IHC-Fr. Rabbit polyclonal. Reacts with: Hu. Predicted: Ms, Rat ...
http://www.abcam.com/index.html?t=272897&pt=1&c=2375&ei=&mu=...
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ROM-K (E-20) Antibody sc-10694
Human, KCNJ1, 3758, 11q24.3, NM_000220, NM_153764, NM_153765, NM_153766, NM_153767 · P48048 · 600359. Mouse, Kcnj1, 56379, 9 A4, O88335 ...
http://www.scbt.com/datasheet-10694-rom-k-e-20-antibody.html...
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Complete Solutions for Ion Channels
KCNJ1, NM_153764, potassium inwardly-rectifying channel: subfamily J: member 1, P0856. KCNJ2, NM_008425, potassium inwardly-rectifying channel: subfamily J: ...
http://www.sigmaaldrich.com/life-science/functional-genomics...
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WNK4 antibody (ab3965) | Abcam
It also inhibits the renal K(+) channel KCNJ1 via a kinase independent mechanism , by which it induces clearance of the protein from the cell surface by ...
http://www.abcam.com/WNK4-antibody-ab3965.html...
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ROM-K (N-17) Antibody sc-10692
... Protein Accession #, OMIM™ Number. Human, KCNJ1, 3758, 11q24.3, NM_000220, NM_153764, NM_153765, NM_153766, NM_153767 · P48048 ...
http://www.scbt.com/datasheet-10692-rom-k-n-17-antibody.html...
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Abcam antibodies and reagents product map
... Inositol Hexakisphosphate Kinase 2 antibodies (2) · KCNIP1 antibodies (1) · KCNJ1 antibodies (2) · Mucolipin 1 antibodies (6) · NCKX2 antibodies (1) ...
http://www.abcam.com/index.html?c=2105...
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ROM-K siRNA (m) sc-42633
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Kcnj1, 56379, 9 A4, O88335 ...
http://www.scbt.com/datasheet-42633-rom-k-sirna-m.html...
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