Tuesday November 24 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

Rac1


Suggest Content
Advertise Here
Gene DB Home
Symbol:Rac1
Name(s):Rac1
Type:protein-coding
Organism:Drosophila melanogaster
Synonyms:CG2248, D-Rac, D-Rac 1, D-Rac1, DRac, DRac1, DRacA, Dm Rac1, DmRAC1, Drac1a, GTPase Rac1, Rac, Rac GTPase, RacA
Links: Pubmed, Entrez Gene, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17629483 Reducing activity of the Egfr, Vav, or Rac1 from somatic support cells enhanced the germ cell enclosure defects of a conditional Spitz allele.
17616927 Rho GTPases may have partially overlapping functions during planar cell polarity generation
17438281 These results reveal a role for chimaerin in the regulation of ERK signaling and cell-cell adhesion and have implications for its participation in epithelial development and tumor progression.
16621891 Rac1 induces Bsk activity and stable actin formation for cellular immune activation, leading to sessile hemocyte release and an increase in the number of circulating hemocytes.
11919634 Rac1, Rac2 and Mtl, have overlapping functions in the control of epithelial morphogenesis, myoblast fusion, and axon growth and guidance
11919635 axon growth, guidance and branching could be controlled by differential activation of Rac signalling pathways
15936337 Rac plays multiple roles in epithelial sheet fusion, including dorsal closure.
14750960 Both Rac1 and Cdc42 activation induced large growth cones and long filopodia, but Cdc42 did so more efficiently than Rac1. Only Rac1 activation, however, induced thick actin bundles in the filopodia.
16125691 Rac1 is involved in the regulation of myoblast proliferation and segregation during adult myogenesis.
16412417 regulation of cadherin-based adherens junctions by Rac is critical for salivary gland morphogenesis and that this regulation occurs through dynamin-mediated endocytosis

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDchickadee CG9553-PA, isoform A [Drosophila melanogaster].Rac1 CG2248-PA [Drosophila melanogaster].Profilin interacts with Rac.-Pubmed
BINDRac1 CG2248-PA [Drosophila melanogaster].thread CG12284-PA, isoform A [Drosophila melanogaster].DIAP1 interacts with Rac.-Pubmed
BINDRac1 CG2248-PA [Drosophila melanogaster].tricornered CG8637-PA [Drosophila melanogaster].Trc interacts with Rac1.-Pubmed
BINDRac1 CG2248-PA [Drosophila melanogaster].PAK-kinase CG10295-PC, isoform C [Drosophila melanogaster].PAK interacts with Rac1. This interaction was modelled on a demonstrated interaction between Drosophila Rac1 and PAK from an unspecified species.-Pubmed

Press Releases on Rac1:

BioPortfolio Logo
ExonHit Presents Therapeutic and Diagnostic Programs for Alzheimer's at ICAD 2008 2nd July, 2008 ExonHit Therapeutics SA

PARIS and GAITHERSBURG, Maryland, July 2 /PRNewswire-FirstCall/ -- ExonHit Therapeutics (ALTERNEXT-NYSE EURONEXT : ALEHT ; ISIN : FR0004054427), a drug and diagnostic company, today announced

Rac1 results (if any) from reagent suppliers

Google CSE Logo
Rac1 antibody (ab15880) | Abcam
Chicken polyclonal to Rac1. This protein is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear
...
http://www.abcam.com/Rac1-antibody-ab15880.html...

Thumbshot
Phospho-Rac1/cdc42 (Ser71) Antibody #2461
Phospho-Rac1/cdc42 (Ser71) Antibody detects endogenous levels of Rac1/cdc42 only when phosphorylated at serine 71. The antibody may also recognize ...
http://www.cellsignal.com/products/2461.html...

Thumbshot
Rac 1 (C-14) Antibody sc-217
See how others have used Rac 1 (C-14): sc-217 antibody and or Rac 1 (C-14) antibody ... Phospholipase D-mediated activation of IQGAP1 through Rac1
regulates ...
http://www.scbt.com/datasheet-217-rac-1-c-14-antibody.html...

Thumbshot
Rac1/2/3 Antibody #2465
Rac1/2/3 Antibody detects endogenous levels of total Rac1/2/3 proteins. This antibody does not cross-react with other small GTPases. ...
http://www.cellsignal.com/products/2465.html...

Thumbshot
Rac 1 (C-11) Antibody sc-95
See how others have used Rac 1 (C-11): sc-95 antibody and or Rac 1 (C-11) ... Western blot analysis of Rac 1 expression in non-transfected: sc-117752 (A) ...
http://www.scbt.com/datasheet-95-rac-1-c-11-antibody.html...

Thumbshot
Rac1/2/3 (L129) Antibody #2467
Polyclonal antibodies are produced by immunizing rabbits with a synthetic peptide corresponding to the sequence of human Rac1/2/3. ...
http://www.cellsignal.com/products/2467.html...

Thumbshot
Rac 1 (T-17) Antibody sc-6084
See how others have used Rac 1 (T-17): sc-6084 antibody and or Rac 1 (T-17) ... Western blot analysis of Rac 1 expression in mouse embryo tissue extract. ...
http://www.scbt.com/datasheet-6084-rac-1-t-17-antibody.html...

Thumbshot

Search Bioportfolio and other Life Science Sites for Rac1, or search for Rac1 on BioPortfolio's antibody search engine.
This page has been viewed 92 times
Recent Search Terms used to find this page: .


Resources from the
NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.