Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18248681 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 18292785 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18325906 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17325155 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17347568 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 17352366 |
Observational study of genotype prevalence and gene-disease association. (HuGE Navigator) |
| 17426452 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17456821 |
Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator) |
| 17884985 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18054635 |
Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 18061132 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18079691 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 18161619 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18162041 |
Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator) |
| 18164066 |
Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator) |
| 18079691 |
Although a role for PLEKHA1 could not be totally excluded, there was a four times higher age-related macular degeneration risk was associated with haplotype "A-T-A" involving "PLEKHA1-LOC387715-HTRA1" risk alleles. |
| 18162041 |
Polymorphisms in the complement factor H gene, LOC387715, and the HTRA1 promoter are strongly associated with age-related macular degeneration. |
| 18054635 |
The Age-related macular degeneration associated complement factor H Y402H and LOC387715 A69S variants were associated with differences in choroidal neovascular lesion size in this study. |
| 17884985 |
SNP rs10490924 represents a major susceptibility variant for age-related macular degeneration. A likely biological mechanism is that the A69S change in the LOC387715/ARMS2 protein affects its presumptive function in mitochondria. |
| 17692272 |
The LOC387715/HTRA1 variants are associated with polypoidal choroidal vasculopathy (PCV) and wet age-related macular degeneration (AMD) in the Japanese population. |
| 17846368 |
Both ARMS2 polymorphism and complement factor H polymorphism are independently associated with progression of age-related macular degeneration. |
| 16642439 |
Our results strongly implicate a coding change (Ala69Ser) in the LOC387715 gene as the second major identified AMD-susceptibility allele, confirming earlier suggestions. This variant's effect on AMD is statistically independent of CFH . |
| 17285240 |
findings suggest that the combined effect of variants in the CFH and LOC 387715 genes may contribute to the age-related macular degeneration phenotype in this family |
| 17000705 |
study provides additional support for the CFH and LOC387715 genes in age-related maculopathy (ARM) susceptibility via the evaluation of cohorts that had different ascertainment schemes regarding ARM status and through the meta-analyses |
| 16174643 |
Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk. |
| 17194541 |
A polymorphism of LOC387715 gene is associated with age-related macular degeneration in the Japanese population. |
| 16954704 |
Results further support the notion that CFH (complement factor H) and LOC387715 genes are the major risk factors for ARMD. |
| 17347568 |
The number of risk alleles at the LOC387715 SNP was associated with advanced Age-related macular degeneration |
| 17325155 |
AMD (age-related macular degeneration) genetic risk marker harbored within LOC387715, the nested case-control data from the population-based BMES samples showed lower estimates than from the clinic-based samples. |
