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MAFA


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Symbol:MAFA
Name(s):v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
Type:protein-coding
Organism:Homo sapiens
Synonyms:RIPE3b1, hMafA
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
14973194 MafA selectively induces endogenous insulin transcription in non-beta cells
17636040 MafA has a critical role in islet beta-cell function
15993959 Co-expression and functional synergism of these beta-cell enriched transactivators, MafA, Pdx1, and Beta2, are critical for establishing the beta-cell-specific and efficient expression of the insulin gene.
15664997 mafA has a role in regulating insulin gene expression in the liver
15665000 MafA plays a key role in coordinating and controlling the level of insulin gene expression in islet beta cells.
16847327 Data show that FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDInsulin promoter factor 1v-maf musculoaponeurotic fibrosarcoma oncogene homolog A--Pubmed
HPRDv-maf musculoaponeurotic fibrosarcoma oncogene homolog isoform av-maf musculoaponeurotic fibrosarcoma oncogene homolog A--Pubmed
HPRDNeurogenic differentiation factor 1v-maf musculoaponeurotic fibrosarcoma oncogene homolog A--Pubmed

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
5230893 Stable agrochemical compositions including alpha-unsaturated amine derivative and acid incorporated into a carrier
5713519 Fluid spraying system
6034227 DNA molecule encoding a mast cell function-associated antigen (MAFA)
6423501 Calcium-independent negative regulation by CD81 of receptor signaling

View more patents.

MAFA results (if any) from reagent suppliers

Google CSE Logo
MAFA antibody (ab26405) | Abcam
Rabbit polyclonal to MAFA. Insulin gene expression is regulated by several islet -enriched transcription factors. However, MAFA is the only beta ...
http://www.abcam.com/MAFA-antibody-ab26405.html...

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MafA (F-12) Antibody sc-27140
MafA shRNA (h) Lentiviral Particles, sc-43905-V, 200 µl ... Western blot analysis of MafA expression in mouse eye (A) and mouse pancreas (B) tissue
extracts ...
http://www.scbt.com/datasheet-27140-mafa-f-12-antibody.html...

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MafA Antibody Bethyl Laboratories
MafA is a member of the Maf basic leucine-zipper containing transcription factor family. MafA is an islet-enriched protein that plays a role in beta ...
http://www.bethyl.com/product/A300-611A/MafA_Antibody/AAAAAA...

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Anti-MAFA Polyclonal Antibody
Polyclonal Antibody against MAFA for use in ChIP assay, Gel Shift, Immunohistochemistry (Frozen), Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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MafA (H-12) Antibody sc-27139
goat polyclonal IgG, 200µg/ml; epitope mapping within an internal region of MafA of human origin; recommended for detection of MafA of human origin by WB, ...
http://www.scbt.com/datasheet-27139-mafa-h-12-antibody.html...

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mouse KLRG1 antibody, Allophycocyanin (APC) conjugate
This 2F1 monoclonal antibody reacts with the mouse Killer cell Lectin-like Receptor G1 (KLRG1), also known as Mast cell Function-associated Antigen (MAFA).
...
http://www.ebioscience.com/ebioscience/specs/antibody_17/17-...

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MAFA peptide (ab28523) | Abcam
MAFA peptide. Insulin gene expression is regulated by several islet-enriched transcription factors. However, MAFA is the only beta cell-specific activator.
http://www.abcam.com/MAFA-peptide-ab28523.html...

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