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L1CAM
| Symbol: | L1CAM | | Name(s): | L1 cell adhesion molecule | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAML1, S10, SPG1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18059459 |
A soluble form of human L1 can be detected in the urine of patients with acute tubular necrosis and this may be a marker of distal nephron injury. |
| 17952127 |
Expression of L1-CAM augments cell motility, invasiveness and tumor growth, causes sustained Erk kinase activation and augments transcriptional activity of proinvasive genes. |
| 11393533 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 11425011 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16650578 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 17420921 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18090124 |
Alpha v beta 5, alpha v beta 5 and their ligands Del-1 and L1 play an important role in the process of tumor cells moving from the original place. |
| 17873897 |
a significant association of L1 expression and presence of disseminated tumor cells colorectal tumors |
| 17211730 |
High L1 expression is associated with colorectal cancer progression |
| 17699774 |
ADAM10 overexpression in colon cancer cells displaying endogenous L1-CAM enhanced L1-CAM cleavage and induced liver metastasis, and ADAM10 also enhanced metastasis in colon cancer cells stably transfected with L1-CAM. | →View more information from publications. |
Recent Publications on L1CAM: |  |
Stimulation of glioma cell motility by expression, proteolysis, and release of the L1 neural cell recognition molecule.
ABSTRACT: BACKGROUND: Malignant glioma cells are particularly motile and... | 31st October, 2009
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| Cancer Cell Int. 2009 Oct 29;9(1):27.
DOI Direct Link |
Prenatal identification of a novel R937P L1CAM missense mutation.
The L1 cell adhesion molecule (L1CAM) is a protein encoded by a gene that... | 27th October, 2009
| Section of Maternal Fetal Medicine, Department of Obstetrics and
| Genet Test Mol Biomarkers. 2009 Aug;13(4):515-9.
DOI Direct Link |
Genotype-phenotype correlations in L1 syndrome: a guide for genetic counselling and mutation analysis.
OBJECTIVES: L1 syndrome is an X-linked recessive disorder for which we... | 23rd October, 2009
| 1 Department of Genetics, University Medical Centre Groningen, University
| J Med Genet. 2009 Oct 20.
DOI Direct Link |
DNA hypomethylation at the CpG island is involved in aberrant expression of the L1 cell adhesion molecule gene in colorectal cancer.
The L1 cell adhesion molecule (L1CAM) has been identified as a target gene... | 2nd October, 2009
| Department of Pathology, Iwate Medical University School of Medicine, 18-1
| Int J Oncol. 2009 Sep;35(3):467-76.
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The AA genotype of a L1C G842A polymorphism is associated with an increased risk for ovarian cancer.
BACKGROUND: Recent studies proposed L1CAM (L1 cell adhesion molecule)... | 1st October, 2009
| Institute of Pharmacogenetics, University of Duisburg-Essen, Hufelandstr.
| Anticancer Res. 2009 Aug;29(8):3449-52.
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→View more research publications. |
L1CAM results (if any) from reagent suppliers | 
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L1CAM antibody [2C2] - Neuronal Marker (ab24345) | Abcam
Mouse monoclonal [2C2] to L1CAM - Neuronal Marker. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS ...
http://www.abcam.com/L1CAM-antibody-2C2-Neuronal-Marker-ab24...
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L1CAM antibody, L1CAM [UJ127.11] Antibody, Mouse Monoclonal Antibody
Buy quality mouse L1CAM antibody (interacts with human - not yet tested in other ... Mouse monoclonal [UJ127.11] to L1CAM; Neural cell adhesion molecule L1, ...
http://www.genwaybio.com/product_info.php?products_id=193052...
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L1CAM antibody [74-5H7] (ab24704) | Abcam
Mouse monoclonal [74-5H7] to L1CAM . The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of ...
http://www.abcam.com/L1CAM-antibody-74-5H7-ab24704.html...
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Anti-L1CAM Monoclonal Antibody
Monoclonal Antibody against L1CAM for use in Immunohistochemistry, Immunoprecipitation, Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...
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L1CAM proteins and peptides: Neuroscience > Neurology process ...
L1CAM proteins and peptides. ... L1CAM proteins and peptides. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication ...
http://www.abcam.com/index.html?t=13735&pt=2&c=3358&ei=&mu=r...
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Antibody Products - Protein and Antibody Solutions Provider - GenWay
L1CAM; antigen identified by monoclonal antibody R1; CD171; HGNC:7086; HSAS1; ... Mouse monoclonal [UJ127] to L1CAM; Neural cell adhesion molecule L1 ...
http://www.genwaybio.com/all_monoclonal_antibodies.php?fl=L...
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NCAM-L1 (H-200) Antibody sc-15326
L1CAM, INP10, P-cadherin, tPA and ITGB4 over-expression in malignant pleural mesotheliomas revealed by combined use of cDNA and tissue microarray. ...
http://www.scbt.com/datasheet-15326-ncam-l1-h-200-antibody.h...
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