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ACAT2


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Gene DB Home
Symbol:ACAT2
Name(s):acetyl-Coenzyme A acetyltransferase 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18269457 ACAT-2 expression was negative in clear cell type renal cell carcinoma and normal kidney.
12621162 Observational study of gene-disease association. (HuGE Navigator)
14557872 Observational study of gene-disease association. (HuGE Navigator)
15158756 Observational study of gene-disease association. (HuGE Navigator)
16195894 Observational study of gene-disease association. (HuGE Navigator)
17919884 Observational study of gene-disease association. (HuGE Navigator)
18000807 ACAT2 expression was induced upon R1881 (androgen agonist) treatment in prostate cancer cells
17950700 human ACAT2 is transcriptionally regulated by cholesterol.
15733928 Data describe the high resolution structure of human cytosolic acetoacetyl-CoA thiolase (CT), both unliganded (at 2.3 angstroms resolution) and in complex with CoA (at 1.6 angstroms resolution).

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDacetyl-Coenzyme A acetyltransferase 2caudal type homeobox 2--Pubmed
HPRDacetyl-Coenzyme A acetyltransferase 2caudal type homeobox 2--Pubmed

Recent Publications on ACAT2:

Pubmed Logo
Estrogen decreases atherosclerosis in part by reducing hepatic acyl-CoA:cholesterol acyltransferase 2 (ACAT2) in monkeys.
OBJECTIVE: Estrogens decrease atherosclerosis progression, mediated in...
30th September, 2009
Department of Pathology, Section on Comparative Medicine, Wake Forest Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1471-7.
DOI Direct Link
Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.
The purpose of the present study was to identify genetic variants that...
25th September, 2009
Department of Cardiovascular Medicine, Inabe General Hospital, Inabe, Int J Mol Med. 2009 Aug;24(2):233-46.
Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function.
Parkin is an ubiquitin-protein ligase (E3), mutations of which cause...
3rd September, 2009
Section of Ophthalmology and Neuroscience, Leeds Institute for Molecular Proteomics. 2009 Sep;9(18):4284-97.
DOI Direct Link
Role of cholesterol pathways in norovirus replication.
Norwalk virus (NV) is a prototype strain of the noroviruses (family...
1st September, 2009
Department of Diagnostic Medicine and Pathobiology, College of Veterinary J Virol. 2009 Sep;83(17):8587-95. Epub 2009 Jun 10.
DOI Direct Link
TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation.
High levels of the inflammatory cytokine tumor necrosis factor-alpha...
13th August, 2009
State Key Laboratory of Molecular Biology, Institute of Biochemistry and J Lipid Res. 2009 Jun;50(6):1057-67. Epub 2009 Feb 2.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
6100077 Isolation of a gene encoding diacylglycerol acyltransferase
7045326 Mono- and diacylglycerol acyltransferases and methods of use thereof
7122559 Phenylglycine derivatives useful as serine protease inhibitors
7144895 Benzene acetamide compounds useful as serine protease inhibitors
7151113 Pyrazole-amine compounds useful as kinase inhibitors

View more patents.

ACAT2 results (if any) from reagent suppliers

Google CSE Logo
Cayman Chemical | ACAT-2 Polyclonal Antibody | Description ...
4,2 Human ACAT-2 has 522 amino acid with an estimated molecular weight of 60 kDa . 5 Cayman's antibody detects ACAT-2 at about 60 kDa in murine liver, ...
http://www.caymanchem.com/app/template/Product.vm/catalog/10...

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SOAT2 (ACAT-2) Antibody sc-69837
SOAT2 (ACAT-2): sc-69837. Western blot analysis of SOAT2 expression in Hep G2 whole cell lysate. Download. Datasheets · Get Adobe Acrobat Reader ...
http://www.scbt.com/datasheet-69837-soat2-acat-2-antibody.ht...

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ACAT2 antibody (ab66259) | Abcam
Rabbit polyclonal to ACAT2. Acetyl-Coenzyme A acetyltransferase 2 is an enzyme involved in lipid metabolism. Reported patients with ACAT2 deficiency have ...
http://www.abcam.com/ACAT2-antibody-ab66259.html...

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ACAT-2 (N-15) Antibody sc-30279
Western blot analysis of ACAT-2 expression in Hep G2 whole cell lysate (A) and ... ACAT-2 (N-15): sc-30279. Western blot analysis of ACAT-3 expression in ...
http://www.scbt.com/datasheet-30279-acat-2-n-15-antibody.htm...

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ACAT2 Recombinant Protein acetyl-Coenzyme A acetyltransferase 2 ...
ACAT2 Recombinant Protein from ProSci Incorporated. Protein GI number 5174389, accesion number NP_005882.,
http://www.prosci-inc.com/shop/catalog1/ACAT2-Recombinant-Pr...

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ACAT2 antibodies: Cardiovascular > Lipids / Lipoproteins > Lipid ...
ACAT2 antibodies. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab37467 · ACAT2 antibody. WB. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=115090&pt=1&c=855&ei=&mu=r...

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ACAT-2 (m): 293T Lysate sc-118189
100 µg protein in 200 µl SDS-PAGE buffer; suitable as Western Blotting control for ACAT-2 antibodies; mouse ACAT-2 transfected 293T lysate; suitable control
...
http://www.scbt.com/datasheet-118189-acat-2-m-293t-lysate.ht...

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