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LAG3
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15674389 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16519819 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17020785 |
Observational study of gene-disease association. (HuGE Navigator) |
| 12775570 |
LAG-3 induces rapid protein phosphorylation of phospholipase Cgamma2 and p72syk as well as activation of phosphatidyl inositol 3-kinase/Akt, p42/44 extracellular signal-regulated protein kinase, and p38 mitogen-activated protein kinase pathways. |
| 14644131 |
LAG-3 activates antigen-presenting cells through MHC class II signalling, leading to increased antigen-specific T-cell responses in vivo. |
| 12825348 |
LAG3 may mediate sphingolipid metabolism |
| 17020785 |
The result, including a total of 2640 MS patients and 2194 controls shows no significant association with CD4 and LAG3 and MS. We conclude that these genes are of minor importance in regard of genetic predisposition to the MS. |
| 16757686 |
regulatory T cells and LAG-3 have pivotal roles in the suppression of EBV-specific cell-mediated immunity in Hodgkin lymphoma |
| 11937541 |
MHC class II-mediated signals induced by the natural ligand, LAG-3, lead to complete maturation of monocyte-derived dendritic cells, which acquire the capacity to trigger naive T cells and drive polarized Th1 responses. |
Recent Publications on LAG3: |  |
CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2.
Regulatory T cells (Tregs) are engaged in the maintenance of immunological... | 9th October, 2009
| Department of Allergy and Rheumatology, Graduate School of Medicine,
| Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13974-9. Epub 2009 Aug 4.
DOI Direct Link |
Microarray analysis of lymphatic tissue reveals stage-specific, gene expression signatures in HIV-1 infection.
Untreated HIV-1 infection progresses through acute and asymptomatic stages... | 7th August, 2009
| Department of Microbiology, School of Public Health, University of
| J Immunol. 2009 Aug 1;183(3):1975-82. Epub 2009 Jul 13.
DOI Direct Link |
Molecular cloning and expression analysis of pig lymphocyte activation gene-3 (LAG-3; CD223).
Lymphocyte activation gene-3 (LAG-3; CD223) is a co-receptor that may... | 28th July, 2009
| School of Life Sciences and Biotechnology, Korea University, Seoul
| Vet Immunol Immunopathol. 2009 Jul 10.
DOI Direct Link |
The transcription factor ATF5: role in neurodevelopment and neural tumors.
We review recent findings regarding the properties of ATF5 and the major... | 9th April, 2009
| Department of Pathology and Cell Biology Columbia University College of
| J Neurochem. 2009 Jan;108(1):11-22. Epub 2008 Nov 15.
DOI Direct Link |
LAG-3 regulates plasmacytoid dendritic cell homeostasis.
Lymphocyte activation gene 3 (LAG-3) is a CD4-related, activation-induced... | 5th March, 2009
| Department of Immunology, St. Jude Children's Research Hospital, Memphis,
| J Immunol. 2009 Feb 15;182(4):1885-91.
DOI Direct Link |
→View more research publications. |
LAG3 results (if any) from reagent suppliers | 
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mouse CD223 antibody, Affinity Purified conjugate
eBioscience technical data sheet for product 14-2231 Affinity Purified anti- mouse CD223 (LAG3, LAG-3) eBioC9B7W (C9B7W) antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_14/14-...
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Purified Anti-mouse CD223 LAG-3 Antibody Anti-CD223 - BioLegend
Purified Anti-mouse CD223 LAG-3 Antibody Anti-CD223 - CD223, also known as LAG-3 , is 70 kD type I transmembrane glycoprotein within the Ig superfamily.
http://www.biolegend.com/purified-anti-mouse-cd223-lag-3-ant...
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mouse CD223 antibody, Serum conjugate
This polyclonal rabbit serum recognizes mouse CD223 (LAG-3, LAG3) ... Rabbit anti-mouse CD223/LAG3 polyclonal serum has been reported for use in ELISA. ...
http://www.ebioscience.com/ebioscience/specs/antibody_24/24-...
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Mouse LAG-3 Affinity Purified Polyclonal Ab
extracellular domain of LAG-3 contains a V-set and three C2-set Ig domains. LAG- 3 is expressed on activated T cells, NK cells and B cells. It binds to MHC ...
http://www.rndsystems.com/pdf/AF3328.pdf...
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LAG-3 (mouse):Fc (mouse) (recombinant) - Enzo Life Sciences
LAG-3 0 mouse Fc human recombinant,CD Proteins • Recombinant Proteins / Fusion Proteins,Immunology,Dendritic Cells [DC],Binds to human and mouse MHC class ...
http://www.enzolifesciences.com/ALX-522-099/lag-3-mouse-fc-m...
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Polyclonal Anti-human LAG-3-Phycoerythrin
mature LAG-3 protein is a 496 amino acid (aa) membrane protein with a 421 aa extracellular region which contains four IgSF ...
http://www.rndsystems.com/pdf/FAB2319P.pdf...
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eBioscience BestProtocols: ELISA, Cytokine Antibody Pairs
LAG-3, sCD223, eBioC9B7W, 14-2231, Polyclonal, 24-2232, please inquire, please inquire. MCP-1, 4E2, 14-7091, 2H5, 13-7096, 15 - 2000, please inquire ...
http://www.ebioscience.com/ebioscience/appls/ELISApr.htm...
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