Thursday November 26 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

LALBA


Suggest Content
Advertise Here
Gene DB Home
Symbol:LALBA
Name(s):lactalbumin, alpha-
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC138521, MGC138523
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12833543 pH-dependent stability of the alpha-lactalbumin molten globule state.
15134431 The electrostatic nature of the alpha-lactalbumin (LA)-histone interaction justifies use of alpha-LA as a basis for design of antitumor agents, acting through disorganization of chromatin structure due to interaction between alpha-LA and histone.
16851644 Results describe the reaction mechanism and formation of CIDNP (chemically induced dynamic nuclear polarization) in the photoreactions of the dye 2,2'-dipyridyl with non-native states of bovine and human alpha-lactalbumins in aqueous solution.
15558602 the non-cooperative denaturation of the molten globule, alpha-lactalbumin secondary structure elements are stabilized by non-specific, non-native interactions
11718563 comparison of the structural and stability properties of the isolated alpha-helical domain of lysozyme with that of alpha-lactalbumin
15956205 Fold and topology of alpha-lactalbumin may be formed from degenerate groups of side chains.
15075403 NMR study of the conformation of HAMLET, the folding variant of human alpha-lactalbumin, complexed to oleic acid.
12860137 Structural characterisation of the human alpha-lactalbumin molten globule at high temperature
14627739 a functional Ca(2+)-binding site is not required for conversion of alpha-lactalbumin to the active complex or to cause cell death
14627740 lipids are tissue-specific cofactors in alpha-lactalbumin protein folding

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCrystallin, alpha Alactalbumin, alpha- precursor--Pubmed
HPRDcrystallin, alpha ALactalbumin alpha--Pubmed
HPRDUDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound formlactalbumin, alpha- precursor--Pubmed
HPRDUDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound formlactalbumin, alpha- precursor--Pubmed
HPRDLactalbumin alphahistone cluster 2, H2be--Pubmed
HPRDlactalbumin, alpha- precursorHistone 2, H2BE--Pubmed

Recent Publications on LALBA:

Pubmed Logo
Maternal progesterone treatment rescues the mammary impairment following uteroplacental insufficiency and improves postnatal pup growth in the rat.
Uteroplacental insufficiency in the rat reduces maternal progesterone and...
26th June, 2009
Department of Physiology, The University of Melbourne, Victoria, Reprod Sci. 2009 Apr;16(4):380-90. Epub 2009 Jan 22.
DOI Direct Link
Cell turnover and gene activities in sheep mammary glands prior to lambing to involution.
Mammary glands are special tissue characterized by proliferation of the...
31st March, 2009
Dipartimento di Scienze Animali, University of Udine, via delle Scienze, Tissue Cell. 2009 Oct;41(5):326-33. Epub 2009 Mar 27.
DOI Direct Link
[Correlations between SNP of LALBA gene and economic traits in Inner Mongolian white cashmere goat]
PCR-SSCP and DNA sequencing methods were conducted to detect single...
18th March, 2009
College of Animal Science and Technology, Northwest A & F University, Yi Chuan. 2008 Feb;30(2):169-74.
Lack of functional alpha-lactalbumin prevents involution in Cape fur seals and identifies the protein as an apoptotic milk factor in mammary gland involution.
BACKGROUND: The mammary gland undergoes a sophisticated programme of...
10th January, 2009
CRC for Innovative Dairy Products, Department of Zoology, University of BMC Biol. 2008 Nov 6;6:48.
DOI Direct Link
Differences between the radiation hybrid and genetic linkage maps of bovine chromosome 5 resolved with a quasi-phylogenetic method of analysis.
Two major differences were detected in gene order between the radiation...
8th June, 2000
CSIRO Tropical Agriculture, Molecular Animal Genetics Centre, Level 3 Mamm Genome. 2000 May;11(5):369-72.

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7485158 Method of dyeing the textile article from medicinally rich herbs
7368113 Hormonally up-regulated, neu-tumor-associated kinase
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

LALBA results (if any) from reagent suppliers

Google CSE Logo
L0888 Anti-α-Lactalbumin antibody produced in rabbit fractionated ...
species reactivity, human. packaging, vial of 2 mL. application(s), immunoelectrophoresis: suitable. Gene Information, human ... LALBA(3906).
storage temp. ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=L088...

Thumbshot
α-lactalbumin (S-17) Antibody sc-51456
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Lalba, 16770, 15 F1, P29752 ...
http://www.scbt.com/datasheet-51456-alpha-lactalbumin-s-17-a...

Thumbshot
Antibodies to Human Plasma Proteins
fractionated antiserum, human ... LALBA(3906), human, IEP, pricing. L8266, Anti- α-Lipoprotein (HDL) antibody produced in goat, (polyclonal), whole antiserum ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

Thumbshot
α-lactalbumin (F20.16) Antibody sc-53151
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, LALBA, 3906, 12q13.11, NM_002289 ...
http://www.scbt.com/datasheet-53151-alpha-lactalbumin-f20-16...

Thumbshot
L7269 α-Lactalbumin from human milk ≥95% (SDS-PAGE), lyophilized ...
assay, ≥95% (SDS-PAGE). form, lyophilized powder. mol wt, mol wt 14070 Da by calculation. Gene Information, human ... LALBA(3906). storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

Thumbshot
Lactalbumin Antibody / Lactalbumin Antibodies
제품명, 카탈로그 번호, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. α-lactalbumin (0 .N.14) Antibody, sc-58672, mouse IgM, FL (h), WB, IF, human ...
http://www.scbt.com/ko/table-lactalbumin.html...

Thumbshot

Search Bioportfolio and other Life Science Sites for LALBA, or search for LALBA on BioPortfolio's antibody search engine.
This page has been viewed 123 times
Recent Search Terms used to find this page:
alpha-Lactalbumin antitumor mechanism | LACTALBUMIN ALPHA CAS | lactalbumin | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.