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LAMA5
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17000025 |
The major contributions of laminin-5 to the resistance of the epidermis against frictional stress but also for basement membrane regeneration and repair of damaged skin are reflected by the phenotype of Herlitz junctional epidermolysis bullosa. |
| 17482449 |
LM-332 is a crucial motility-promoting factor for B-CLL lymphocytes and is a potential constituent favoring the dissemination of B-CLL lymphocytes through vascular basement membranes and possibly lymph node compartments. |
| 17888902 |
The results indicate that glioma cells secrete alpha2-, alpha4- and alpha5-laminins and that alpha3- and alpha5-laminins, selectively promote glioma cell migration and identify alpha3beta1 as the predominant integrin and laminin receptor in glioma cells. |
| 16870608 |
Ln-5 is an important regulator of ADPKD cell proliferation and cystogenesis; Ln-5 gamma(2) chain and Ln-5-alpha(6)beta(4) integrin interaction both contribute to these phenotypic changes |
| 16723698 |
laminin 5 and p16INK4A have roles in wound healing and senescence |
| 15967115 |
prostate cancer cells expressing high levels of MT1-MMP have increased invasive potential through their ability to degrade and invade Ln-10 barriers |
| 14612440 |
proteolytic processing of laminin-5 influences its interaction with alpha3beta1 integrin |
| 15302884 |
cAMP-Epac-Rap1 pathway regulates cell spreading and cell adhesion to laminin-5 through the alpha3beta1 integrin but not the alpha6beta4 integrin |
| 16226104 |
An increase was noted in LAMA5 immunostaining in the dilated muscle of the ganglionic bowel upstream the distal aganglionic region in a group of Hirschprung disease patients. |
| 12682087 |
Our results elucidate a mechanism whereby mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane. | →View more information from publications. |
Recent Publications on LAMA5: |  |
A role for pericytes as microenvironmental regulators of human skin tissue regeneration.
The cellular and molecular microenvironment of epithelial stem and... | 3rd October, 2009
| Research Division, Peter MacCallum Cancer Centre, St Andrew's Place,
| J Clin Invest. 2009 Sep;119(9):2795-806. doi: 10.1172/JCI38535. Epub 2009
DOI Direct Link |
Identification of a novel family of laminin N-terminal alternate splice isoforms: structural and functional characterization.
The laminins are a family of heterotrimeric basement membrane proteins... | 24th September, 2009
| Northwestern University, United States;
| J Biol Chem. 2009 Sep 22.
DOI Direct Link |
Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia.
Schizophrenia is a complex neurodevelopmental disorder that is thought to... | 14th May, 2009
| Department of Molecular Animal Physiology, Donders Institute for Brain,
| J Psychiatr Res. 2009 Oct;43(15):1195-9. Epub 2009 May 10.
DOI Direct Link |
Analysis of genes encoding laminin beta2 and related proteins in patients with Galloway-Mowat syndrome.
Galloway-Mowat syndrome (GMS) is a rare autosomal recessive disorder... | 19th November, 2008
| Institute of Human Genetics, University of Erlangen-Nuremberg,
| Pediatr Nephrol. 2008 Oct;23(10):1779-86. Epub 2008 Jul 2.
DOI Direct Link |
Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: potential role in progression.
Recurrent karyotypic abnormalities are a characteristic feature of... | 1st November, 2008
| Department of Pathology, Columbia University Medical Center, New York, NY
| Genes Chromosomes Cancer. 2008 Sep;47(9):755-65.
DOI Direct Link |
→View more research publications. |
LAMA5 results (if any) from reagent suppliers | 
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Laminin α-5 (H-160) Antibody sc-20145
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, LAMA5, 3911, 20q13.33, NM_005560 ...
http://www.scbt.com/datasheet-20145-laminin-alpha-5-h-160-an...
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Abgent - Cell and Structure Antibodies - Cell_structure
AT2668aNEW, LAMA2 monoclonal antibody (M01), ELISA,IHC-P,WB-Re, H. AT2669aNEW, LAMA5 monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H ...
http://www.abgent.com/products/category/cell_function/cell_s...
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Laminin alpha 5 antibody (ab55413) | Abcam
Laminin alpha 5 (LAMA5) belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Laminin alpha 5 is the alpha chain ...
http://www.abcam.com/laminin-alpha-5-antibody-ab55413.html...
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