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LAMB3
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15370542 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15149852 |
co-cultures of epithelial cells and fibroblasts were studied to analyse the processing of laminin 5 alpha3, beta3, and gamma2 chains |
| 17476356 |
Multiple second-site mutations, all correcting the germline mutation LAMB3 (628G-->A;Glu210Lys), are present in 2 unrelated non-Herlitz junctional epidermolysis bullosa patients with revertant mosaicism. |
| 15373767 |
homozygous frameshift mutation in LAMB3 was associated to illegitimate splicing leading to non-H junctional epidermolysis bullosa |
| 11689492 |
Gene LAMB3 detected compound heterozygosity for the nonsense mutation R635X and a novel 2 bp deletion (1587delAG) resulting in a downstream premature termination codon. |
| 16147969 |
DNA analysis revealed a compound heterozygote for mutations 2379delG and Q995X in the LAMB3 gene in Herlitz junctional epidermolysis bullosa |
| 15331737 |
Deletion analysis of laminin-beta3 indicated that the region comprising aa 726 to 875 of laminin-beta3 interacts with rotavirus enterotoxin NSP4. |
| 15363037 |
In squamous cell carcinoma of the tongue and colorectal carcinoma, laminin 5 beta3 chain is important in the invasiveness of cancer cells. |
| 15854126 |
the absolute mRNA levels generated from the laminin 5 genes do not determine the translated protein levels of the laminin 5 chains in keratinocytes; the expression of the laminin 5 genes may be controlled by common regulation mechanisms |
Recent Publications on LAMB3: |  |
A deregulated immune response to gliadin causes a decreased villus height in DQ8 transgenic mice.
Celiac disease (CD) is an enteropathy triggered by gluten and mediated by... | 2nd October, 2009
| Institute of Food Sciences, CNR, Avellino, Italy.
| Eur J Immunol. 2009 Sep 30.
DOI Direct Link |
TNFR and LTbetaR agonists induce follicle-associated epithelium and M cell specific genes in rat and human intestinal epithelial cells.
M cells assist mucosal immune surveillance by transcytosis of particles to... | 22nd September, 2009
| Division of Biomedical Sciences, University of California, Riverside, CA
| Cytokine. 2009 Jul;47(1):69-76. Epub 2009 Jun 5.
DOI Direct Link |
Partial deletion of the LAMA3 gene is responsible for hereditary junctional epidermolysis bullosa in the American Saddlebred Horse.
Laminin 5 is a heterotrimeric basement membrane protein integral to the... | 13th March, 2009
| Department of Veterinary Science, University of Kentucky, Lexington, KY
| Anim Genet. 2009 Feb;40(1):35-41. Epub 2008 Nov 11.
DOI Direct Link |
Clinical significance of LAMB3 and COL7A1 mRNA in esophageal squamous cell carcinoma.
AIMS: LAMB3 and COL7A1 genes code for the laminin-5beta3 chain and type... | 27th January, 2009
| Department of Surgery, Medical Institute of Bioregulation, Kyushu
| Eur J Surg Oncol. 2009 Jan;35(1):52-8. Epub 2008 Mar 10.
DOI Direct Link |
Prediction of human miRNAs using tissue-selective motifs in 3' UTRs.
MicroRNAs (miRNAs) play an important role in posttranscriptional... | 23rd December, 2008
| Institute of Information Science, Innovation Research Center, and
| Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17061-6. Epub 2008 Oct 24.
DOI Direct Link |
→View more research publications. |
LAMB3 results (if any) from reagent suppliers | 
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Laminin β-3 (H-300) Antibody sc-20775
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, LAMB3, 3914, 1q32.2, NM_000228, ...
http://www.scbt.com/datasheet-20775-laminin-beta-3-h-300-ant...
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Laminin β-3 (h2): 293T Lysate sc-177459
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, LAMB3, 3914, 1q32.2, Q13751 ...
http://www.scbt.com/datasheet-177459-laminin-beta-3-h2-293t-...
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