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LAMP1


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Symbol:LAMP1
Name(s):lysosomal-associated membrane protein 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:CD107a, LAMPA, LGP120
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15916720 Data identify CD13, CD107a, and CD164 as novel basophil-activation antigens.
16778144 CD107a surface expression has a role in Munc13-4 defect in familial hemophagocytic lymphohistiocytosis
16570122 Novel evidence for differential expression of HBGA and LAMPs in proliferative and involutive phases of immunohistochemistry is presented.
16887987 LAMP-1 and DC-LAMP antigen chimeras follow different trafficking pathways, induce distinct modulatory immune responses, and are able to present cryptic epitopes.
15052658 This study identifies two cDNA clones that code for heart extracellular matrix protein, hLAMP-1. Immunohistochemical studies indicate that the myocardial layer of the heart produces hLAMP-1.
16710742 expression in keratinocytes cultured at different cell densities in order to induce differentiation
16718270 Enhanced expression of lysosome-associated membrane protein-1 in melanoma may promote invasion by influencing both adhesion to extracellular matrix and perhaps also binding to endothelial cells.
12144129 review of structure, function, cell and tissue distribution, intracellular trafficking
15744340 Using human leukemia and lymphoma cell lines, we observed a close correlation between CD107a surface expression and target cell lysis, indicating that NK cell cytotoxicity can be assessed by this method.
17048695 LAMP-1 and LAMP-2 may have roles in accidental involution of the thymic gland

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDAP2M1lysosomal-associated membrane protein 1--Pubmed
HPRDadaptor-related protein complex 2, mu 1 subunit isoform aLysosome associated membrane protein 1--Pubmed
HPRDLysosome associated membrane protein 1adaptor-related protein complex 1, mu 1 subunit--Pubmed
HPRDlysosomal-associated membrane protein 1AP47--Pubmed

Recent Publications on LAMP1:

Pubmed Logo
The two-domain LysX protein of Mycobacterium tuberculosis is required for production of lysinylated phosphatidylglycerol and resistance to cationic antimicrobial peptides.
The well-recognized phospholipids (PLs) of Mycobacterium tuberculosis...
3rd November, 2009
Department of Biochemistry, The University of Texas Health Center at PLoS Pathog. 2009 Jul;5(7):e1000534. Epub 2009 Jul 31.
DOI Direct Link
TLR9 activation increases TAP-independent vesicular MHC class I processing in vivo.
Cross-presentation of soluble protein antigens on major histocompatibility...
31st October, 2009
Microbiology, Tumor and Cell Biology (MTC), Karolinska Institute, 171 77 Scand J Immunol. 2009 Nov;70(5):431-8.
DOI Direct Link
The Leishmania donovani lipophosphoglycan excludes the vesicular proton-ATPase from phagosomes by impairing the recruitment of synaptotagmin V.
We recently showed that the exocytosis regulator Synaptotagmin (Syt) V is...
17th October, 2009
INRS-Institut Armand-Frappier and Centre for Host-Parasite Interactions, PLoS Pathog. 2009 Oct;5(10):e1000628. Epub 2009 Oct 16.
DOI Direct Link
Degenerative abnormalities in transgenic neocortical neuropeptide Y interneurons expressing tau-green fluorescent protein.
The introduction of a reporter gene into bacterial artificial chromosome...
16th October, 2009
Laboratoire de Neurobiologie, CNRS UMR 7637, ESPCI ParisTech, Paris, J Neurosci Res. 2009 Oct 14.
DOI Direct Link
Valosin containing protein associated inclusion body myopathy: abnormal vacuolization, autophagy and cell fusion in myoblasts.
Inclusion body myopathy associated with Paget's disease and frontotemporal...
16th October, 2009
Department of Pediatrics, Division of Genetics and Metabolism, University Neuromuscul Disord. 2009 Nov;19(11):766-72. Epub 2009 Oct 13.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
6335170 Gene expression in bladder tumors
6876159 Electronic ballast system for emergency lighting applications
6878562 Method for shifting the bandgap energy of a quantum well layer
6881402 Inhibiting apoptosis with adenovirus RID protein
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases

View more patents.

LAMP1 results (if any) from reagent suppliers

Google CSE Logo
LAMP1 antibody [LY1C6] - Lysosome Marker (ab13523) | Abcam
Mouse monoclonal [LY1C6] to LAMP1 - Lysosome Marker. Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral ...
http://www.abcam.com/LAMP1-antibody-LY1C6-Lysosome-Marker-ab...

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LAMP-1 (H5G11) Antibody sc-18821
LAMP-1 (H5G11): sc-18821. Western blot analysis of LAMP-1 expression in HeLa (A) , JAR (B), ... LAMP-1 (H5G11) PE: sc-18821 PE. FCM analysis of JAR cells. ...
http://www.scbt.com/datasheet-18821-lamp-1-h5g11-antibody.ht...

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The Abcam catalog
LAMP1 antibodies. ... LAMP1 antibody - Drosophila Lysosome Marker ... LAMP1 antibody [1D4B] - BSA and Azide free. Flow Cyt, IP, WB, AP, ICC/IF, IM, IHC-Fr
...
http://www.abcam.com/index.html?t=83752&pt=1&c=444...

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FITC Anti-mouse CD107a LAMP-1 Antibody Anti-CD107a - BioLegend
FITC Anti-mouse CD107a LAMP-1 Antibody Anti-CD107a - CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type
...
http://www.biolegend.com/fitc-anti-mouse-cd107a-lamp-1-antib...

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LAMP-1 Antibody An autophagy related protein
LAMP-1 antibody can be used for the detection of LAMP-1 by Western blot at 1 – 2 ug/ml. (Optimal dilution should be determined by user).
http://www.prosci-inc.com/shop/catalog1/LAMP-1-Antibody-p-63...

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LAMP1 antibody (ab24170) | Abcam
Rabbit polyclonal to LAMP1. Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is ...
http://www.abcam.com/lamp1-antibody-ab24170.html...

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Anti-LAMP1 Polyclonal Antibody
Polyclonal Antibody against LAMP1 for use in Immunofluorescence.
http://www.bioreagents.com/products/productDetails/productDe...

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