Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17464325 |
P-element excision was used to generate mutants of the initiator caspase strica. While null mutants of strica or another initiator caspase, dronc, display no ovary phenotype, strica exhibits redundancy with dronc, during both mid- and late oogenesis. |
| 15173191 |
Direct binding of EcR-Usp is crucial for controlling the timing of dronc expression in specific tissues. |
| 15774476 |
DIAP1 is cleaved by the apical caspase DRONC in both normal and apoptotic Drosophila cells |
| 12356728 |
Jafrac2 displaces Dronc from DIAP1 by competing with Dronc for the binding of DIAP1, consistent with the idea that Jafrac2 triggers cell death by liberating Dronc from DIAP1-mediated inhibition |
| 12011068 |
a novel cell death pathway triggered by DIAP1 depletion depends on Dark and Dronc |
| 15922568 |
Our study places DRONC at a central point of convergence for multiple cell death pathways and for the ecdysone pathway regulating metamorphosis |
| 12970673 |
the dronc promoter is regulated in a highly complex manner |
| 16980627 |
These results show that the apoptotic pathway bifurcates at DRONC and that DRONC coordinates the execution of cell death and compensatory proliferation. |
| 12397080 |
the initial step in DRONC processing occurs continuously via a DARK-dependent mechanism in Drosophila cells and DIAP1 is required to prevent excess accumulation of this first form of processed DRONC |
| 15383617 |
analysis of Dronc activation and processing in Drosophila cells |
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