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LBR


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Gene DB Home
Symbol:LBR
Name(s):lamin B receptor
Type:protein-coding
Organism:Homo sapiens
Synonyms:DHCR14B, LMN2R, MGC9041, PHA
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
14718546 SR protein kinase and cdc2 kinase regulate lamin B receptor binding to chromatin
14701833 examination of temporal association with protamine 1 during spermiogenesis
12118250 Mutations in the gene encoding the lamin B receptor produce an altered nuclear morphology in granulocytes (Pelger-Huet anomaly).
11846796 The binding of lamin B receptor to chromatin is regulated by phosphorylation in the arginine-serine repeat-containing REGION
12618959 Autosomal recessive HEM/Greenberg skeletal dysplasia is caused by 3 beta-hydroxysterol delta 14-reductase deficiency due to mutations in this gene.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDLamin B receptorformin binding protein 4--Pubmed
HPRDlamin B receptorSFRS protein kinase 1--Pubmed
HPRDlamin B receptorlamin B1--Pubmed
HPRDlamin B receptorlamin B1--Pubmed
HPRDlamin B receptorchromobox homolog 5--Pubmed
HPRDlamin B receptorchromobox homolog 5--Pubmed
HPRDlamin B receptorA kinase anchor protein 8-like--Pubmed
HPRDlamin B receptorchromobox homolog 3--Pubmed
HPRDlamin B receptorchromobox homolog 3--Pubmed

Recent Publications on LBR:

Pubmed Logo
Poor prognosis with in vitro fertilization in Indian women compared to Caucasian women despite similar embryo quality.
BACKGROUND: Disease prevalence and response to medical therapy may differ...
27th October, 2009
Department of Obstetrics and Gynecology, Division of Reproductive PLoS One. 2009 Oct 26;4(10):e7599.
DOI Direct Link
The influence of leg-to-body ratio (LBR) on judgments of female physical attractiveness: Assessments of computer-generated images varying in LBR.
The leg-to-body ratio (LBR), which is reliably associated with...
14th October, 2009
Department of Psychology, University of California, Los Angeles, Body Image. 2009 Oct 10.
DOI Direct Link
Impact of the basal metabolic ratio in predicting early deaths after allogeneic stem cell transplantation.
Early deaths after allogeneic stem cell transplantation (allo-SCT) are of...
9th October, 2009
Am J Hematol. 2009 Sep;84(9):608-11.
DOI Direct Link
Recruitment of functionally distinct membrane proteins to chromatin mediates nuclear envelope formation in vivo.
Formation of the nuclear envelope (NE) around segregated chromosomes...
24th September, 2009
Salk Institute for Biological Studies, Molecular and Cell Biology J Cell Biol. 2009 Jul 27;186(2):183-91. Epub 2009 Jul 20.
DOI Direct Link
A pilot study evaluating the safety of vaginal administration of a multi-particulate pellet formulation.
AIM: Quantitative evaluation of the effect caused by vaginal...
8th September, 2009
Laboratory of Bacteriology Research (LBR), Ghent University, Ghent, Eur J Pharm Biopharm. 2009 Sep 4.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
A School-Based HIV/STD Prevention Program to Reduce Risky Sexual Behaviors Among Adolescents in Liberia

Patents:

Patents logo
US Patent No.Title
7352686 Limited play optical devices with interstitial reactive layer and methods of making same
7424357 Lane departure prevention apparatus
7429690 Transgenic bovines having reduced prion protein production
7443978 Method and apparatus for audio coding with noise suppression
7448532 360 degree rotatable lifter arm for log singulator

View more patents.

LBR results (if any) from reagent suppliers

Google CSE Logo
Lamin B Receptor antibody [E398L] (ab32535) | Abcam
Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner
...
http://www.abcam.com/Lamin-B-Receptor-antibody-E398L-ab32535...

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Anti-HP1a antibody produced in rabbit (H2164) - Datasheet
the lamin B receptor (LBR). This interaction can contribute to the association of heterochromatin with the inner nuclear membrane. 7. HP1α or HP1β were also
...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

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HP1 alpha antibody (ab16482) | Abcam
HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear ...
http://www.abcam.com/hp1-alpha-antibody-ab16482.html...

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Lamin B receptor siRNA (m) sc-146641
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Lbr, 98386, 1 H5, Q3U9G9 ...
http://www.scbt.com/datasheet-146641-lamin-b-receptor-sirna-...

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L1293dat Anti-Lamin A _C-terminal_ KAA,PHC 12-05-1
(lamina-associated polypeptides), LBR (lamin B receptor) and emerin. 5. They also interact with chromatin and nuclear pore complexes. ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

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Lamin B receptor siRNA (h) sc-88544
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, LBR, 3930, 1q42.12, NM_002296, ...
http://www.scbt.com/ja/datasheet-88544-lamin-b-receptor-sirn...

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Anti-Lamin A-Atto 647N (L3544) - Data Sheet
associated polypeptides), LBR (Lamin B receptor) and emerin.5 They also interact with chromatin and nuclear pore complexes.4 ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

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