Sunday November 22 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

LDLR


Suggest Content
Advertise Here
Gene DB Home
Symbol:LDLR
Name(s):low density lipoprotein receptor (familial hypercholesterolemia)
Type:protein-coding
Organism:Homo sapiens
Synonyms:FH, FHC
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18097620 Observational study of gene-disease association. (HuGE Navigator)
18206115 Observational study of genetic testing. (HuGE Navigator)
18210030 Observational study of gene-disease association. (HuGE Navigator)
18243212 Observational study of gene-disease association. (HuGE Navigator)
18261733 Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18288382 Observational study of gene-disease association. (HuGE Navigator)
18296645 Observational study of gene-disease association. (HuGE Navigator)
18307033 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18317771 Observational study of gene-disease association. (HuGE Navigator)
18354102 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDapolipoprotein B precursorlow density lipoprotein receptor precursor--Pubmed
HPRDapolipoprotein B precursorlow density lipoprotein receptor precursor--Pubmed
HPRDapolipoprotein E precursorlow density lipoprotein receptor precursor--Pubmed
HPRDapolipoprotein E precursorlow density lipoprotein receptor precursor--Pubmed
HPRDDAB1low density lipoprotein receptor precursor--Pubmed
HPRDdisabled homolog 1Low density lipoprotein receptor--Pubmed
HPRDheat shock 70kDa protein 5low density lipoprotein receptor precursor--Pubmed
HPRDheat shock 70kDa protein 5low density lipoprotein receptor precursor--Pubmed
HPRDLow density lipoprotein receptorlow density lipoprotein receptor adaptor protein 1--Pubmed
HPRDlow density lipoprotein receptor precursorLDL receptor adaptor protein--Pubmed

Recent Publications on LDLR:

Pubmed Logo
Regulation of cellular immunity prevents Helicobacter pylori-induced atherosclerosis.
Helicobacter pylori (H. pylori) is a predominant pathogen that causes not...
3rd November, 2009
Department of Bacteriology, Okayama University Graduate School of Lupus. 2009 Nov;18(13):1154-68.
DOI Direct Link
Anti-atherosclerotic actions of azelaic acid, an end product of linoleic acid peroxidation, in mice.
BACKGROUND: Atherosclerosis is a chronic inflammatory disease associated...
3rd November, 2009
Division of Cardiothoracic Surgery, Ohio State University Medical Center, Atherosclerosis. 2009 Oct 12.
DOI Direct Link
PCSK9 is expressed in pancreatic delta-cells and does not alter insulin secretion.
PCSK9 (Proprotein Convertase Subtilisin Kexin type 9) is a proprotein...
3rd November, 2009
INSERM, U915, Nantes F-44000, France. Biochem Biophys Res Commun. 2009 Oct 27.
DOI Direct Link
Dietary Fish Oil Exerts Hypolipidemic Effects in Lean and Insulin Sensitizing Effects in Obese LDLR-/- Mice.
Obesity is often associated with dyslipidemia, insulin resistance, and...
30th October, 2009
Department of Molecular Physiology and Biophysics, Vanderbilt University J Nutr. 2009 Oct 28.
DOI Direct Link
Long-term Physiologically Regulated Expression of the Low-density Lipoprotein Receptor In Vivo Using Genomic DNA Mini-gene Constructs.
Familial hypercholesterolemia (FH) is a condition caused by mutations in...
29th October, 2009
Department of Physiology, Anatomy and Genetics, University of Oxford, Mol Ther. 2009 Oct 27.
DOI Direct Link

View more research publications.

BioNews Results for LDLR

: RSS Logo
BioPortfolio Logo
Low pH-Triggered Beta-Propeller Switch of the Low-Density Lipoprotein Receptor Assists Rhinovirus Infection
MDLinx:  Oct 12 2009 12:52PM Matching: ldlr

Clinical Trials:

Clinical Trials Logo
LDL Receptor Under Ezetimibe and Simvastatin

Patents:

Patents logo
US Patent No.Title
7405302 5-lipoxygenase-activating protein (FLAP) inhibitors
7473418 Pan cancer oncolytic vectors and methods of use thereof
7473525 Compositions and methods for inhibiting expression of anti-apoptotic genes
7473770 Cynomolgus monkey dickkopf-4, nucleotides encoding same, and uses thereof
7482334 Therapeutic treatment methods

View more patents.

LDLR results (if any) from reagent suppliers

Google CSE Logo
LDLR Antibody / LDLR Antibodies
LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDLR, LRP, Megalin, VLDLR and apoER2. ...
http://www.scbt.com/table-ldlr.html...

Thumbshot
Cayman Chemical | LDL Receptor Polyclonal Antibody | Description ...
2 LDLR expression is under hormonal control both in vivo and in vitro. Mutations in the LDLR gene cause disorders such as familial hypercholesterolemia and ...
http://www.caymanchem.com/app/template/Product.vm/catalog/10...

Thumbshot
LDLR (C7) Antibody sc-18823
Mutations in LDLR cause the autosomal dominant disease familial ... Western blot analysis of LDLR expression in bovine adrenal tissue extract. ...
http://www.scbt.com/datasheet-18823-ldlr-c7-antibody.html...

Thumbshot
LDLR monoclonal antibody (M01)
Western Blot analysis of LDLR expression in transfected 293T cell line by LDLR ... Detection limit for recombinant GST tagged LDLR is approximately 0.3ng/ml
...
http://www.abgent.com/products/catalog_no/AT2690a_LDLR_monoc...

Thumbshot
LDLR (H-120) Antibody sc-20744
See how others have used LDLR (H-120): sc-20744 antibody and or LDLR (H-120) ... Western blot analysis of LDLR expression in CCD-1064Sk whole cell lysate. ...
http://www.scbt.com/datasheet-20744-ldlr-h-120-antibody.html...

Thumbshot
LDL Receptor antibody (ab14056) | Abcam
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligand...
http://www.abcam.com/LDL-Receptor-antibody-ab14056.html...

Thumbshot
Phospho-LRP6 (Ser1490) Antibody
of the LDLR family, LRP5 and LRP6 have four EGF and three. LDLR repeats in the extracellular domain and proline-rich motifs in the cytoplasmic domain (1). ...
http://www.cellsignal.com/pdf/2568.pdf...

Thumbshot

Search Bioportfolio and other Life Science Sites for LDLR, or search for LDLR on BioPortfolio's antibody search engine.
This page has been viewed 219 times
Recent Search Terms used to find this page:
LDLr precursor | plasmid LDLR gene | familial Hypercholesterolaemia Lupus | LDLR C-20 sc-11824 | sc-11824 | familial hypercholesterolemia - endocytosis news | ldlr gene environmental | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.