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FADS1


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Symbol:FADS1
Name(s):fatty acid desaturase 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:D5D, FADS6, FADSD5, FLJ38956, FLJ90273, LLCDL1, TU12
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18320251 Observational study of gene-disease association. (HuGE Navigator)
16670158 Observational study of gene-disease association. (HuGE Navigator)
16893529 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17852835 The results indicate that when the supply of FA to HL60 cells is limited, the intracellular content of n-3 and n-6 FA decreases and this leads to upregulation of the desaturases, particularly D5D and D6D.
17655842 SREBP-1 is involved in the early regulation of delta5 desaturase gene by simvastatin, in THP-1 cells.
16643857 This is the first report on characterization of human FADS, and the first cloning and over-expression of FADS from an organism higher than yeast.
16670158 FADS1 FADS2 genetic varients and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids
16846730 support a significant role for reverse Delta5-desaturase as a natural antisense regulator of Delta5-desaturase

Recent Publications on FADS1:

Pubmed Logo
Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism.
PURPOSE OF REVIEW: The delta-5 and delta-6 desaturases have long been...
8th October, 2009
aInstitute of Epidemiology, Helmholtz Zentrum Munchen, German Research Curr Opin Lipidol. 2009 Oct 3.
DOI Direct Link
Genetic determinants of circulating sphingolipid concentrations in European populations.
Sphingolipids have essential roles as structural components of cell...
3rd October, 2009
Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), PLoS Genet. 2009 Oct;5(10):e1000672. Epub 2009 Oct 2.
DOI Direct Link
FADS gene cluster polymorphisms: important modulators of fatty acid levels and their impact on atopic diseases.
Long-chain polyunsaturated fatty acids (LC-PUFAs) play an important role...
25th September, 2009
Institute of Epidemiology, Helmholtz Zentrum Munchen, German Research J Nutrigenet Nutrigenomics. 2009;2(3):119-28. Epub 2009 Sep 23.
DOI Direct Link
The fatty acid desaturase 3 (Fads3) gene encodes for different FADS3 protein isoforms in mammalian tissues.
In the year 2000, Marquardt et al. described the genomic structure of the...
16th September, 2009
USC INRA2012 Agrocampus Ouest, France; J Lipid Res. 2009 Sep 14.
DOI Direct Link
Novel fatty acid desaturase 3 (FADS3) transcripts generated by alternative splicing.
Fatty acid desaturase 1 and 2 (FADS1 and FADS2) code for the key...
1st September, 2009
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, Gene. 2009 Oct 1;446(1):28-34. Epub 2009 Jun 30.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Essential Fatty Acids During Complementary Feeding

Patents:

Patents logo
US Patent No.Title
7091033 Array of toxicologically relevant canine genes and uses thereof
4549263 Device interface controller for input/output controller

FADS1 results (if any) from reagent suppliers

Google CSE Logo
FADS1 (V-21) Antibody sc-101953
Western blot analysis of FADS1 expression in Jurkat whole cell lysate. sc-101953 . FADS1 (V-21): sc-101953. Immunoperoxidase staining of formalin fixed, ...
http://www.scbt.com/datasheet-101953-fads1-v-21-antibody.htm...

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FADS1 antibodies: Cardiovascular > Lipids / Lipoproteins > Fatty ...
FADS1 antibodies. ... FADS1 antibody. WB, ELISA, sELISA. Images. Mouse monoclonal. Reacts with: Hu, RecFrag. Predicted: Pig. ab83298 · FADS1 antibody
...
http://www.abcam.com/index.html?t=237235&pt=1&c=868&ei=&mu=r...

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FADS Antibody / FADS Antibodies
FADS1 (V-21) Antibody, sc-101953, rabbit IgG, N/A, WB, IP, IF, IHC(P), ELISA ... FADS1 (7-RY13) Antibody, sc-134337, mouse IgG2a, N/A, WB, IP, ELISA, human ...
http://www.scbt.com/ko/table-fads.html...

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Abcam antibodies and reagents product map
... DOLPP1 antibodies (1) · DPM1 antibodies (1) · ERLIN1 antibodies (1) · FADS1 antibodies (3) · FKBP10 antibodies (2) · FVT1 antibodies (1) · GCS1.
http://www.abcam.com/index.html?cl=251&pageconfig=productmap...

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FADS1 siRNA (h) sc-96474
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: FADS1 ...
http://www.scbt.com/ja/datasheet-96474-fads1-sirna-h.html...

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FADS1 (V-21) Antibody sc-101953
FADS1 (V-21) 抗体 sc-101953 FADS1 (V-21) Antibody sc-101953.
http://www.scbt.com/ja/datasheet-101953-fads1-v-21-antibody....

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