BioPortfolio - Nedd4

Nedd4

Symbol:

Nedd4

Name(s):

Nedd4

Type:

protein-coding

Organism:

Drosophila melanogaster

Synonyms:

CG7555, DNedd4, dNedd4-1

Links:

Pubmed, Entrez Gene, Map Viewer.

Gene Information from Publications

Publication Link

Summary of findings

17074801

dNedd4 and ubiquitination are required for Commissureless endocytosis and proper neuromuscular synaptogenesis.

15620649

Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation.

16531238

These studies provide insights into the specific regulation of dNedd4-mediated ubiquitination of Comm and subsequent internalization of Comm or the Comm/Roundabout complex, critical for CNS and muscle development.

Interacting gene products

Interaction Type

Gene 1

Gene 2

Interaction description

Complex

Publication Link

BIND

Notch CG3936-PA [Drosophila melanogaster].

Nedd4 CG7555-PA, isoform A [Drosophila melanogaster].

Nedd4 interacts with and ubiquitnates Notch.

Pubmed

Nedd4 results (if any) from reagent suppliers

NEDD4 Antibody #2740
NEDD4 (neural precursor expressed, developmentally down-regulated protein 4) was originally identified as a gene that is highly expressed in the early mouse ...
http://www.cellsignal.com/products/2740.html...

NEDD4 antibody (ab14592) | Abcam
Rabbit polyclonal to NEDD4. Nedd4 is one of a group of mouse genes that show developmentally regulated expression in mouse embryonic brain.
http://www.abcam.com/nedd4-antibody-ab14592.html...

NEDD4-1 (H-135) Antibody sc-25508
See how others have used NEDD4-1 (H-135): sc-25508 antibody and or NEDD4-1 (H- 135) ... Western blot analysis of NEDD4 expression in KNRK whole cell lysate.
...
http://www.scbt.com/datasheet-25508-nedd4-1-h-135-antibody.h...

NEDD4 Antibody
recently, a family of NEDD4-like proteins has been defined. (7 members in humans ) (2). ... domains of NEDD4 bind to PY motifs (amino acid sequence ...
http://www.cellsignal.com/pdf/2740.pdf...

NEDD4-2 antibody (ab46521) | Abcam
Rabbit polyclonal to NEDD4-2. E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then ...
http://www.abcam.com/NEDD4-2-antibody-ab46521.html...

NEDD4-1 (A-16) Antibody sc-14429
goat polyclonal IgG, 200 µg/ml; epitope mapping within an internal region of NEDD4-1 of human origin; recommended for detection of NEDD4-1 of m, ...
http://www.scbt.com/datasheet-14429-nedd4-1-a-16-antibody.ht...

NEDD4 antibodies: Chromatin and Nuclear Signaling > Cell cycle ...
NEDD4 antibodies. ... NEDD4 antibody. IHC-P, WB, IHC-Fr. Rabbit polyclonal. Reacts with: Ms. Predicted: Hu. ab76341 · NEDD4 antibody. IHC-P, WB, IHC-Fr ...
http://www.abcam.com/index.html?t=91957&pt=1&c=3588&ei=&mu=r...

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