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LMAN1


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Symbol:LMAN1
Name(s):lectin, mannose-binding, 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18025080 ERGIC-53 bound high-mannose-type oligosaccharides with low affinity and broad specificity, not discriminating between monoglucosylated and deglucosylated high-mannosetype oligosaccharides.
11333866 Observational study of gene-gene interaction. (HuGE Navigator)
11561111 Observational study of gene-disease association. (HuGE Navigator)
11607788 Observational study of gene-disease association. (HuGE Navigator)
11992290 Observational study of gene-disease association. (HuGE Navigator)
14593599 Observational study of gene-disease association. (HuGE Navigator)
14732744 Observational study of gene-disease association. (HuGE Navigator)
15166951 Observational study of genotype prevalence. (HuGE Navigator)
17496053 a mannose-binding lectin codon 54 gene polymorphism has a role in protection against Chlamydia trachomatis infection and Fallopian tube damage
17535801 ERGIC-53 gene transcription is regulated in response to endoplasmic reticulum stress

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCoagulation factor VIIIlectin, mannose-binding, 1 precursor--Pubmed
HPRDcoagulation factor VIII isoform a precursorLectin mannose binding 1--Pubmed
HPRDLectin mannose binding 1multiple coagulation factor deficiency 2--Pubmed

Recent Publications on LMAN1:

Pubmed Logo
A review of ERGIC-53: its structure, functions, regulation and relations with diseases.
ERGIC-53 is a type I transmembrane protein. It includes an N-terminal...
8th October, 2009
State Key Laboratory of Experimental Hematology, Institute of Hematology Histol Histopathol. 2009 Sep;24(9):1193-204.
A novel missense mutation causing abnormal LMAN1 in a Japanese patient with combined deficiency of factor V and factor VIII.
Combined deficiency of coagulation factor V (FV) and factor VIII (FVIII)...
30th September, 2009
Department of Pathophysiological Laboratory Sciences, Nagoya University Am J Hematol. 2009 Nov;84(11):738-42.
DOI Direct Link
Lysophosphatidic acid acyltransferase 3 regulates Golgi complex structure and function.
Recent studies have suggested that the functional organization of the...
24th September, 2009
Department of Molecular Biology and Genetics, Cornell University, Ithaca, J Cell Biol. 2009 Jul 27;186(2):211-8.
DOI Direct Link
Combined Factor V and Factor VIII Deficiency.
Combined deficiency of factor V (FV) and factor VIII (FVIII) (F5F8D, or...
12th September, 2009
A. Bianchi Bonomi Hemophilia and Thrombosis Center, Department of Medicine Semin Thromb Hemost. 2009 Jun;35(4):390-9. Epub 2009 Jul 13.
DOI Direct Link
Combined FV and FVIII deficiency.
Inherited deficiencies of plasma proteins involved in blood coagulation...
6th August, 2009
A. Bianchi Bonomi Hemophilia and Thrombosis Center, University of Milan Haemophilia. 2008 Nov;14(6):1201-8.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7585634 Method of predicting risk of lung cancer recurrence, and a composition, kit and microarray for the same
7537896 Androgen-regulated PMEPA1 gene and polypeptides
7211559 Factor VIII compositions and methods

View more patents.

LMAN1 results (if any) from reagent suppliers

Google CSE Logo
Antibodies to ER and Golgi Proteins
rat ... Lman1(116666) human ... LMAN1(3998), mouse, human, rat, IF (i), WB CL, pricing ... HPA002320, Anti-LMAN1 antibody produced in rabbit, (polyclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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LMAN1 proteins and peptides: Signal Transduction > Protein ...
LMAN1 proteins and peptides. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab39824 · LMAN1 peptide (159-173 ) ...
http://www.abcam.com/index.html?t=147246&pt=2&c=3598&ei=&mu=...

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E1031 Anti-ERGIC-53/p58 antibody produced in rabbit affinity ...
LMAN1(3998). rat ... Lman1(116666). mouse ... Lman1(70361). shipped in, dry ice. storage temp. −20°C ... HPA002320, Anti-LMAN1 antibody produced in rabbit ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=E103...

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ERGIC-53 (H-245) Antibody sc-66880
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, LMAN1, 3998, 18q21.32, NM_005570 ...
http://www.scbt.com/datasheet-66880-ergic-53-h-245-antibody....

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Antibody Products - IgG Polyclonal Antibodies - GenWay
LMAN1; ERGIC53; F5F8D; MR60; gp58; FMFD1; MCFD1 - ER-Golgi intermediate compartment 53 kDa protein; Lectin, mannose-binding 1; Gp58; ...
https://www.genwaybio.com/all_polyclonal_antibodies.php?fl=E...

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Mouse SDNSF/MCFD2 Biotinylated Affinity Purified PAb
It is also a component of the MCDF2-LMAN1 (Mannose- binding lectin-1, also known as ERGIC-53) complex that functions as a specific cargo ...
http://www.rndsystems.com/pdf/BAF2556.pdf...

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ERGIC-53 siRNA (m) sc-45247
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Lman1, 70361, 18 E1, Q9D0F3 ...
http://www.scbt.com/datasheet-45247-ergic-53-sirna-m.html...

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