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GNBP1

Symbol:	GNBP1
Name(s):	Gram-negative bacteria binding protein 1
Type:	protein-coding
Organism:	Drosophila melanogaster
Synonyms:	CG6895, DGNBP-1, DGNBP1, GNBP
Links:	Pubmed, Entrez Gene, Map Viewer.

Gene Information from Publications
Publication Link	Summary of findings
14684822	results demonstrate that GNBP1 and PGRP-SA can jointly activate the Toll pathway
14722090	GNBP1 acts upstream of the Toll ligand Spatzle and works in the defense against Gram-positive bacterial infection in Drosophila
17024181	GNBP1 presents a processed form of peptidoglycan for sensing by PGRP-SA and that a tripartite interaction between these proteins and peptidoglycan is essential for downstream signaling.

Interacting gene products
Interaction Type	Gene 1	Gene 2	Interaction description	Complex	Publication Link
BIND	Peptidoglycan recognition protein SA CG11709-PA [Drosophila melanogaster].	Gram-negative bacteria binding protein 1 CG6895-PA [Drosophila melanogaster].	GNBP1 interacts with PGRP-SA.	-	Pubmed

GNBP1 results (if any) from reagent suppliers

Toll Comparative Pathway
Drosophila Toll innate surveillance is mediated by the Gram-negative binding protein 1 (GNBP1) and members of the peptidoglycan recognition protein (PGRP)
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http://www.sigmaaldrich.com/life-science/your-favorite-gene-...

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