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Gene DB Home
Symbol:park
Name(s):parkin
Type:protein-coding
Organism:Drosophila melanogaster
Synonyms:CG10523, SD01679, dpk
Links: Pubmed, Entrez Gene, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16818890 Parkin and Pink1 are implicated in a common pathway that regulates mitochondrial physiology and cell survival.
12642658 Mutant forms of this protein result in mitochondrial pathology and apoptotic muscle degeneration.
12670421 interfering with endogenous Drosophila Parkin function promotes Pael-R accumulation and augments its toxicity
15073152 Results report the isolation of a Drosophila homolog of human parkin (PARK2), and characterize its expression and null phenotype.
14646593 The expression pattern of D. melanogaster parkin varies during the developmental stages, and was expressed slightly higher in the central nervous system during the late embryonic stage.
16672981 observations suggest that pink1 and parkin function, at least in part, in the same pathway, with pink1 functioning upstream of parkin; role of the pink1-parkin pathway in regulating mitochondrial function
16002472 Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila.
17123504 Parkin gene function is necessary for mitochondrial morphogenesis during earlier and later phases of spermiogenesis.
15090075 Expression of parkin suppresses the Parkinson disease-like symptoms observed in the alpha-synuclein-dependent Drosophila model of Parkinson disease
16767175 Upregulation of parkin may prove a method of suppression for PD induced by mutant forms of alpha-synuclein.

View more information from publications.

Press Releases on park:

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Narconon of Georgia Celebrates Red Ribbon Drug Awareness Week 30th October, 2009 Narconon of Georgia

ATLANTA, Oct. 30 /PRNewswire/ -- On October 26th, downtown Atlanta played stage to a live band as Narconon of Georgia celebrated Red

park results (if any) from reagent suppliers

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New premises on the Cambridge Science Park | Abcam
New premises on the Cambridge Science Park. Less than two years after its formation, there was sufficient confidence within the company to move from the
...
http://www.abcam.com/index.html?pageconfig=news&rid=10211...

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Parkin antibody, Parkin Antibody, Rabbit Polyclonal Antibody
Rabbit polyclonal to Parkin; FRA6E PARK 2 PARK2 PRKN; E3 ubiquitin-protein ligase parkin, PRKN2_HUMAN. [ N/A NP_004553.2 O60260 ].
http://www.genwaybio.com/product_info.php?products_id=196411...

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mouse CD207 antibody, Biotin conjugate
Idoyaga J, Suda N, Suda K, Park CG, Steinman RM. Antibody to Langerin/CD207 localizes large numbers of CD8alpha+ dendritic cells to the marginal zone of ...
http://www.ebioscience.com/ebioscience/specs/antibody_13/13-...

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Alpha-synuclein Antibody (N-term)
... Non A4 component of amyloid precursor antibody; PARK 1 antibody; PARK 4 antibody; PARK1 antibody; PARK4 antibody; Parkinson disease familial 1 antibody;
...
http://www.abgent.com/products/catalog_no/AP6401a...

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Distributors - Accurate Chemical supplier of Antibodies ...
41 Science Park Road, #04-03A Gemini, Singapore Science Park II, Singapore 117610 info@i-dna.sg, +65 9389 3283, +65 6776 0368 ...
http://www.accuratechemical.com/distributors.asp...

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mouse SIGN-R1 antibody, Functional Gradeā„¢ Purified conjugate
Kang YS, Kim JY, Bruening SA, Pack M, Charalambous A, Pritsker A, Moran TM, Loeffler JM, Steinman RM, Park CG. The C-type lectin SIGN-R1 mediates uptake of
...
http://www.ebioscience.com/ebioscience/specs/antibody_16/16-...

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EY Laboratories, Inc - International Distributors
41 Science Park Road #01-18/20 Gemini Singapore Science Park II SINGAPORE 117610 . Tel. +(65) 9622 1086. Fax.+(65) 6776 0368. NETHERLANDS ...
http://www.eylabs.com/index.php?option=com_content&task=view...

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