Sunday November 22 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

BCAM


Suggest Content
Advertise Here
Gene DB Home
Symbol:BCAM
Name(s):basal cell adhesion molecule (Lutheran blood group)
Type:protein-coding
Organism:Homo sapiens
Synonyms:AU, CD239, LU, MSK19
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18067501 Observational study of genetic testing. (HuGE Navigator)
17638854 The Laminin 511/521-binding site on the Lutheran blood group glycoprotein is located at the flexible junction of Ig domains 2 and 3.
16584446 B-CAM spliceoform seems to be overexpressed by a variety of different malignant tumors and may be involved, along with other adhesion receptor proteins, in malignant transformation and tumor metastasis. (review)
12244066 Results demonstrate that the alpha5 LG3 module is essential for the Lutheran blood group glycoprotein (Lu) binding to laminin alpha5.
14755370 B-CAM/LU is the most critical receptor mediating adhesion to laminin under both static and flow conditions in sickle cell anemia.
16236823 Lu mediates the adhesion of human endothelial cells to alpha5 laminins in collaboration with integrins beta(1) and alpha(v)beta(3).
15278364 interactions of B-CAM and laminin may be involved in progression of epithelial skin tumors

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDlaminin alpha 5Lutheran blood group--Pubmed
HPRDlaminin alpha 5Lutheran blood group--Pubmed

Recent Publications on BCAM:

Pubmed Logo
Stable isotope dilution multidimensional liquid chromatography-tandem mass spectrometry for pancreatic cancer serum biomarker discovery.
A novel approach to pancreatic cancer biomarker discovery has been...
11th July, 2009
Centers for Cancer Pharmacology and Excellence in Environmental J Proteome Res. 2009 Mar;8(3):1565-76.
DOI Direct Link
Red cell and endothelial Lu/BCAM beyond sickle cell disease.
Recent studies shed new lights on the biological function of blood group...
27th February, 2009
Inserm UMR_S 665, Institut national de la transfusion sanguine, 6, rue Transfus Clin Biol. 2008 Dec;15(6):402-5. Epub 2008 Oct 22.
DOI Direct Link
Novel heavy-metal adsorption material: ion-recognition P(NIPAM-co-BCAm) hydrogels for removal of lead(II) ions.
A novel polymeric lead(II) adsorbent is prepared by incorporating...
31st January, 2009
School of Chemical Engineering, Sichuan University, Chengdu, China. J Hazard Mater. 2009 Aug 15;167(1-3):114-8. Epub 2008 Dec 27.
DOI Direct Link
Adhesive activity of Lu glycoproteins is regulated by interaction with spectrin.
The Lutheran (Lu) and Lu(v13) blood group glycoproteins function as...
13th January, 2009
Red Cell Physiology Laboratory, New York Blood Center, NY, USA. Blood. 2008 Dec 15;112(13):5212-8. Epub 2008 Sep 24.
DOI Direct Link
Blood vessels of human islets of Langerhans are surrounded by a double basement membrane.
AIMS/HYPOTHESIS: Based on mouse study findings, pancreatic islet cells are...
22nd October, 2008
Institute of Biomedicine/Anatomy, University of Helsinki, 00014, Helsinki, Diabetologia. 2008 Jul;51(7):1181-91. Epub 2008 Apr 26.
DOI Direct Link

View more research publications.

Press Releases on BCAM:

BioPortfolio Logo
Cancer Research UK Launches Viral Campaign for Breast Cancer Awareness Month 3rd October, 2008

LONDON, October 3 /PRNewswire/ -- Leading brand communications agency, Ogilvy Group UK, this week launches a campaign for its client Cancer Research UK to tie in with Breast Cancer Awareness Month

BioNews Results for BCAM

: RSS Logo
BioPortfolio Logo
Breast Cancer Deception Month: Hiding the Truth beneath a Sea of Pink, Part VI
Natural News:  Nov 14 2009 10:50PM Matching: bcam
Breast Cancer Deception Month: Hiding the Truth beneath a Sea of Pink, Part V
Natural News:  Nov 14 2009 10:50PM Matching: bcam
Breast Cancer Deception Month: Hiding the Truth beneath a Sea of Pink, Part I
Natural News:  Nov 4 2009 11:56AM Matching: bcam
Breast Cancer Deception Month: Hiding the Truth beneath a Sea of Pink, Part IV
Natural News:  Nov 4 2009 11:59AM Matching: bcam
Breast Cancer Deception Month: Hiding the Truth beneath a Sea of Pink, Part III
Natural News:  Nov 4 2009 11:58AM Matching: bcam
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Patents:

Patents logo
US Patent No.Title
4855905 Multiprotocol I/O communications controller unit including emulated I/O controllers and tables translation of common commands and device addresses
5916179 System and method for reducing iatrogenic damage to nerves
5993378 Electro-optical instruments and methods for treating disease
6052383 LAN to ATM backbone switch module
6075718 Method and device for reading a non-erasable memory cell

View more patents.

BCAM results (if any) from reagent suppliers

Google CSE Logo
BCAM Antibody / BCAM Antibodies
BCAM Antibody / BCAM Antibodies. ... BCAM specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-bcam.html...

Thumbshot
Human BCAM MAb (Clone 87207)
extend a vertical line to the x-axis and read the corresponding human BCAM concentration. If samples have been diluted, the ...
http://www.rndsystems.com/pdf/MAB1481.pdf...

Thumbshot
BCAM (B12) Antibody sc-73731
BCAM shRNA (h) Lentiviral Particles, sc-60263-V, 200 µl ... BCAM (B12): sc-73731 . Western blot analysis of BCAM expression in non-transfected: sc-117752 (A) ...
http://www.scbt.com/datasheet-73731-bcam-b12-antibody.html...

Thumbshot
human BCAM DuoSet
human Basal-cell Adhesion Molecule (BCAM). ... mouse anti-human BCAM when reconstituted with 1.0 mL .... when using this human BCAM DuoSet. The standard
...
http://www.rndsystems.com/pdf/DY148.pdf...

Thumbshot
BCAM (3H2010) Antibody sc-70409
Additional BCAM Antibodies . ... BCAM (3H2010) FITC, sc-70409 FITC, 100 tests in 2 ml ... BCAM shRNA (h) Lentiviral Particles, sc-60263-V, 200 µl ...
http://www.scbt.com/datasheet-70409-bcam-3h2010-antibody.htm...

Thumbshot
Matched Antibody Pairs
Human BCAM. MAB1481. 500 µg. Capture. BAF148. 50 µg. Detection (Biotin). 148-BC- 100. 100 µg. Protein. Human BCMA/TNFRSF17 ...
http://www.rndsystems.com/DAM_public/5791.pdf...

Thumbshot
BCAM (C-16) Antibody sc-46795
goat polyclonal IgG, 200µg/ml; epitope mapping near the C-terminus of BCAM of human origin; recommended for detection of mature LU and BCAM precursor of m,
...
http://www.scbt.com/datasheet-46795-bcam-c-16-antibody.html...

Thumbshot

Search Bioportfolio and other Life Science Sites for BCAM, or search for BCAM on BioPortfolio's antibody search engine.
This page has been viewed 430 times
Recent Search Terms used to find this page:
BCAM antibodies | LUTHERAN A BLOOD | j Hazard mater.2009 Aug 15 1-3 114-8.Epub 2008 Dec 27 pdf | lutheran bcam western blot | basal cell adhesion molecule review | laminin B-cam skin | lutheran blood group glycoprotein | Laminin BCAM | lutheran blood | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.