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TACSTD2
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17721311 |
This is the first report, to our knowledge, of a homozygous mutation (L186P) in the M1S1 gene found in a Turkish patient. |
| 17878632 |
Detection of GA733 mRNA by qualitative RT-PCR is highly specific for diagnosis of malignant pleural and peritoneal effusions. |
| 17898270 |
Although mutations in TACSTD2 among Iranian patients with GDLD were heterogeneous, E227K was found to be a common mutation. It is suggested that E227K may be a founder mutation in this population |
| 17653040 |
study reports two novel mutations in two gelatinous drop-like corneal dystrophy families and expands the spectrum of mutations in TACSTD2 gene that may cause pathological corneal amyloidosis |
| 17768381 |
It is concluded that Gelatinous Drop-like Corneal Dystrophy (GDLD) in the pedigree is probably not caused by mutations in TACSTD2, supporting evidence for the existence of at least one other locus for GDLD. |
| 15295654 |
The affected members had compound heterozygous mutations consisting of a nonsense change at codon 84 (K84X) and a missense mutation resulting in a substitution of arginine for cysteine at codon 108 (C108R). |
| 12036680 |
The Q118X mutation of the M1S1 gene can produce either a gelatinous drop-like region or band-shaped opacities. |
| 16232198 |
abnormal transcription of TACSTD2 and S100A2 are thought to be unique molecular markers of the preinvasive stage of lung adenocarcinoma |
| 15013888 |
Because the compound heterozygote mutations Q118X and Y184C cosegregated with the phenotype, they are likely the cause of GDLD (gelatinous droplike corneal dystrophy) in this patient. |
| 15652848 |
The results confirm that the missense mutation L186P in the TACSTD2 gene is also responsible for the GDLD (gelatinous droplike dystrophy) phenotype. | →View more information from publications. |
Recent Publications on TACSTD2: |  |
Exclusion of known corneal dystrophy genes in an autosomal dominant pedigree of a unique anterior membrane corneal dystrophy.
PURPOSE: With advances in phenotyping tools and availability of molecular... | 29th October, 2009
| Department of Ophthalmology, New Zealand National Eye Centre, Faculty of
| Mol Vis. 2009 Aug 26;15:1700-8.
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A novel TACSTD2 mutation identified in two Chinese brothers with gelatinous drop-like corneal dystrophy.
PURPOSE: To identify the molecular defect causing gelatinous drop-like... | 29th October, 2009
| Henan Key Laboratory of Keratopathy, Henan Eye Institute, Zhengzhou, PR
| Mol Vis. 2009 Aug 14;15:1580-8.
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Elevated expressions of MMP7, TROP2, and survivin are associated with survival, disease recurrence, and liver metastasis of colon cancer.
PURPOSE: Colorectal cancer is one of the most common cancers worldwide. We... | 9th September, 2009
| Department of Colorectal Surgery, State Key Laboratory of Oncology in
| Int J Colorectal Dis. 2009 Aug;24(8):875-84. Epub 2009 May 7.
DOI Direct Link |
Accumulating progenitor cells in the luminal epithelial cell layer are candidate tumor initiating cells in a Pten knockout mouse prostate cancer model.
The PSA-Cre;Pten-loxP/loxP mouse prostate cancer model displays clearly... | 21st July, 2009
| Department of Pathology, Josephine Nefkens Institute, Erasmus MC,
| PLoS One. 2009 May 22;4(5):e5662.
DOI Direct Link |
Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice.
In order to identify new genes with differential expression in early... | 17th July, 2009
| Molecular and Population Genetics Laboratory, London Research Institute,
| Hum Mol Genet. 2008 Dec 15;17(24):3864-75. Epub 2008 Sep 9.
DOI Direct Link |
→View more research publications. |
TACSTD2 results (if any) from reagent suppliers | 
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TROP-2 (C-12) Antibody sc-103908
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, TACSTD2, 4070, 1p32.1, P09758 ...
http://www.scbt.com/datasheet-103908-trop-2-c-12-antibody.ht...
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Anti-Human TROP-2
(Tumor-Associated Calcium Signal Transducer 2 (TACSTD2), EGP-1, GA733, GA733-1, M1S1, T16, GP50). Monoclonal Antibody ...
http://www.leinco.com/Monoclonal-Antibody/Anti-Human-TROP-2/...
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Antibody Products - IgG Monoclonal Antibodies - GenWay
Mouse monoclonal [B72.3] to TAG72 ; 4070; TACSTD2; 137290; P09758; EGP-1; GA733; GA733-1; M1S1; TROP2;; 4070; TACSTD2; 137290; P09758; EGP-1; GA733; ...
http://www.genwaybio.com/all_monoclonal_antibodies.php?fl=T...
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TROP2 Antibody (Center)
Tumor-associated calcium signal transducer 2; Pancreatic carcinoma marker protein GA733-1; Cell surface glycoprotein Trop-2; TROP2; M1S1; GA733-1; TACSTD2
...
http://www.abgent.com/products/catalog_no/AP6681c_TROP2_Anti...
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TROP-2 (M-80) Antibody sc-98473
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Tacstd2, 56753, 6 C1, NP_064431 ...
http://www.scbt.com/datasheet-98473-trop-2-m-80-antibody.htm...
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Polyclonal Anti-mouse TROP-2-APC
transducer 2 (TACSTD2), GA733 tumor associated antigen and epithelial glycoprotein-1 (EGP-1), is a type I transmembrane protein highly expressed in
...
http://www.rndsystems.com/pdf/FAB1122A.pdf...
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de•novo
(TACSTD2), GA733-1, gp50 and T16] is a type I cell surface glycoprotein that is highly expressed on human carcinomas.1. It consists of a putative 26 amino ...
http://www.rndsystems.com/DAM_public/5322.pdf...
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