Sunday November 22 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

TACSTD1


Suggest Content
Advertise Here
Gene DB Home
Symbol:TACSTD1
Name(s):tumor-associated calcium signal transducer 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:CD326, CO17-1A, EGP, EGP40, Ep-CAM, GA733-2, KSA, M4S1, MIC18, MK-1, TROP1, hEGP-2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18025791 The spatiotemporal expression pattern of EpCAM changes during nephrogenesis
17981779 analysis of EpCAM expression in normal, non-pathological tissues
18006828 EpCAM is a Wnt-beta-catenin signaling target gene
17186549 downregulation of EGP-2 promoter activity using zinc finger protein transcription factors may result in a novel anti-cancer treatment.
15922867 EpCAM shown to be signal transducing membrane protein involved in carcinogenesis via its ability to induce genes involved in cellular metabolism and proliferation
16096650 The carcinoma-specific epithelial glycoprotein-2 promoter controls efficient and selective gene expression in an adenoviral context.
12642870 amplification is induced by mutations in TP53
15637741 Ep-CAM was distributed differently in normal and various malignant colon tissues. MAbs against Ep-CAM may have diagnostic and therapeutic value to various colon carcinomas.
15557427 EpCAM is vastly expressed in retinoblastoma; EpCAM reactivity was significantly higher in the invasive than the noninvasive tumors and in poorly differentiated than in well-differentiated tumors
17579117 claudin-7-associated EpCAM is recruited into (tetraspanin-enriched membrane microdomains) and forms a complex with CO-029 and CD44v6 that facilitates metastasis formation

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDtumor-associated calcium signal transducer 1 precursortumor-associated calcium signal transducer 1 precursor--Pubmed

Recent Publications on TACSTD1:

Pubmed Logo
Molecular characterization of cultured adult human liver progenitor cells.
Hepatic progenitor cells hold great promise as a self-renewing cell source...
31st October, 2009
Max Planck Institute for Molecular Genetics, Vertebrate Genomics, Tissue Eng Part C Methods. 2009 Oct 29.
DOI Direct Link
JNK1 activation predicts the prognostic outcome of the human hepatocellular carcinoma.
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common...
21st October, 2009
Graduate Center for Toxicology, University of Kentucky, Lexington, Mol Cancer. 2009 Aug 17;8:64.
DOI Direct Link
[EpCAM a proteolytically cleaved oncogene and an excellent therapeutic target in cancer]
ABSTRACT: INTRODUCTION: The ability to screen blood of early stage...
12th September, 2009
Ludwig-Maximilians-University, et Helmholtz Center Munich, Germany. Med Sci (Paris). 2009 May;25(5):449-50.
Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome.
It was shown that Lynch syndrome can be caused by germline...
10th September, 2009
Department of Genetics, University Medical Center Groningen, University of Genes Chromosomes Cancer. 2009 Aug;48(8):737-44.
DOI Direct Link
Overexpression of epithelial cell adhesion molecule in primary, metastatic, and recurrent/chemotherapy-resistant epithelial ovarian cancer: implications for epithelial cell adhesion molecule-specific immunotherapy.
To evaluate the potential of epithelial cell adhesion molecule...
2nd September, 2009
Department of Obstetrics, Gynecology & Reproductive Sciences, Yale Int J Gynecol Cancer. 2009 Jul;19(5):860-6.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Study in EpCAM Positive Patients With Symptomatic Malignant Ascites Using Removab Versus an Untreated Control Group

Patents:

Patents logo
US Patent No.Title
7608394 Methods and compositions for phenotype identification based on nucleic acid methylation
7569354 Cellomics system
7537894 Methods and kits for monitoring Barrett's metaplasia
7531300 Method of diagnosing breast cancer
7504225 Reagents and methods for use in cancer diagnosis, classification and therapy

View more patents.

TACSTD1 results (if any) from reagent suppliers

Google CSE Logo
EpCAM antibody, EpCAM [AUA1] Antibody, Mouse Monoclonal Antibody
Mouse monoclonal [AUA1] to EpCAM; 4072; TACSTD1; 185535; P16422; CO17-1A; EGP; EGP40; Ep-CAM; GA733-2; KSA; M4S1; MIC18; MK-1; TROP1; hEGP-2;; ...
http://www.genwaybio.com/product_info.php?products_id=193057...

Thumbshot
Ep-CAM (H-70) Antibody sc-20154
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, TACSTD1, 4072, 2p21, NM_002354 ...
http://www.scbt.com/datasheet-20154-ep-cam-h-70-antibody.htm...

Thumbshot
ESA antibody, ESA [B29.1 (VU-ID9)] (Biotin) Antibody, Mouse ...
Gene Name: ESA, Gene Name Synonym: 4072; TACSTD1; 185535; P16422; CO17-1A; ... Synonym Names for ESA antibody: ESA; 4072; TACSTD1; 185535; P16422; CO17-1A; ...
http://www.genwaybio.com/product_info.php?products_id=193594...

Thumbshot
mouse EpCAM antibody, Allophycocyanin (APC) conjugate
... adhesion molecule), also known as EGP40 (epithelial glycoprotein 40), 17-1A antigen, TACSTD1 (tumor-associated calcium signal transducer 1), and CD326. ...
http://www.ebioscience.com/ebioscience/specs/antibody_17/17-...

Thumbshot
Ep-CAM (G8.8) Antibody sc-53532
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Mouse, Tacstd1, 17075, 17 E4, NP_032558 ...
http://www.scbt.com/datasheet-53532-ep-cam-g8-8-antibody.htm...

Thumbshot
CD Marker Products - R&D Systems
CD326, EpCAM, 17-1A, GA733-2, gp40, KS1/4, M4S1, TACSTD1, TROP1, 4072. CD327, Siglec-6, CD33L1, OB-BP1, 946. CD328, Siglec-7, AIRM1, QA79, 27036 ...
http://www.rndsystems.com/cdmarker.aspx...

Thumbshot

Search Bioportfolio and other Life Science Sites for TACSTD1, or search for TACSTD1 on BioPortfolio's antibody search engine.
This page has been viewed 512 times
Recent Search Terms used to find this page:
tacstd1 gene | TACSTD1 | epcam germline | TACSTD1 gene Lynch | tacstd1 gene | tacstd1 | epithelial cell adhesion molecule tumor-associated calcium signal transducer 1 | methodes of cdmarker | tacstd1 lynch | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.