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MAD2L1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17210994 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17268814 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) |
| 18022368 |
Data suggest that p31(comet)(CMT2) exploits the two-state behavior of Mad2 to block its activation by acting as an "anti-Mad2." |
| 18022367 |
Data suggest that the structure of the O-Mad2-C-Mad2 conformational dimer is consistent with a catalytic model in which a C-Mad2 template facilitates the binding of O-Mad2 to Cdc20, the target of Mad2 in the spindle checkpoint. |
| 17621272 |
The evidence presented here provides a link between MAD2 inactivation and malignant transformation of epithelial cells. |
| 17998396 |
PRP4 is a spindle assembly checkpoint protein required for MAD2 localization to the kinetochores. |
| 17934339 |
Mad2 is negatively regulated by p31 in heptacellular carcinoma |
| 17498870 |
BUB1B mRNA levels but not MAD2L1 levels correlate with intrachromosomal insttability in ductal breast carcinomas. |
| 15013707 |
No apparent selection trend was established with neoplastic progression or aneuploidy for MAD2 in Barrett esophagus. |
| 15024386 |
The unusual two-state behavior of Mad2 is critical for spindle checkpoint signaling. | →View more information from publications. |
Recent Publications on MAD2L1: |  |
Modulations of cell cycle checkpoints during HCV associated disease.
BACKGROUND: Impaired proliferation of hepatocytes has been reported in... | 9th October, 2009
| Department of Biological and Biomedical Sciences, Aga Khan University,
| BMC Infect Dis. 2009 Aug 10;9:125.
DOI Direct Link |
VHL loss causes spindle misorientation and chromosome instability.
Error-free mitosis depends on fidelity-monitoring checkpoint systems that... | 22nd September, 2009
| Institute of Cell Biology, ETH Zurich, 8093 Zurich, Switzerland.
| Nat Cell Biol. 2009 Aug;11(8):994-1001. Epub 2009 Jul 20.
DOI Direct Link |
Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice.
Aneuploidy is defined as numerical abnormalities of chromosomes and is... | 16th September, 2009
| Department of Medicine, Hematology/Oncology Section, University of
| Carcinogenesis. 2009 Sep;30(9):1469-74. Epub 2009 Apr 16.
DOI Direct Link |
Antibody-based proteomics for esophageal cancer: Identification of proteins in the nuclear factor-kappaB pathway and mitotic checkpoint.
To identify the molecular background of esophageal cancer, we conducted a... | 11th September, 2009
| Proteome Bioinformatics Project, National Cancer Center Research
| Cancer Sci. 2009 Sep;100(9):1612-22. Epub 2009 May 28.
DOI Direct Link |
hBub1 deficiency triggers a novel p53 mediated early apoptotic checkpoint pathway in mitotic spindle damaged cells.
It has been universally believed that spindle assembly checkpoint (SAC)... | 28th August, 2009
| Department of Medicine, Genetics Program and Cancer Research Center,
| Cancer Biol Ther. 2009 Apr;8(7):627-35. Epub 2009 Apr 22.
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→View more research publications. |
MAD2L1 results (if any) from reagent suppliers | 
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