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MAF


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Symbol:MAF
Name(s):v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC71685
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17901057 Pax-6 and c-Maf interact with G1 to activate basal expression of the glucagon gene
17875642 the differential DNA binding specificity between Maf homodimers and Nrf2-Maf heterodimers establishes the differential gene regulation by these dimer-forming transcription factors
18059226 Angioimmunoblastic T-cell lymphoma(AILT) shows c-Maf expression and provide new insight into the pathogenesis of AILT suggesting c-Maf to be a useful diagnostic marker.
17982426 MAF mutation p.Arg299Ser is the third mutation identified in association with the CCMC phenotype, and all three mutations are located in the basic region of the DNA binding domain in the MAF protein (OMIM 177075).
17897790 CD13 transcription is regulatd by MAF via an atypical response element.
17823980 c-Maf is capable of interactions with c-Myb that lead to reduced promoter binding and decreased Bcl-2 expression, rendering CD4 T cells more prone to apoptosis.
14998494 c-maf transforms plasma cells by stimulating cell cycle progression and by altering bone marrow stromal interactions
17044113 OPN is significantly upregulated in MM patients with maf translocations, particularly in the fraction lacking bone disease
12939343 results suggest that Tc-mip plays a critical role in Th2 signaling pathway and represents the first proximal signaling protein which links TCR-mediated signal to the activation of c-maf Th2 specific factor
16498264 Segmental allergen challenge in asthmatics leads to increased GATA-3, c-maf and T-bet expression in BAL cells but not in bronchial biopsies

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCREBBPv-maf musculoaponeurotic fibrosarcoma oncogene homolog isoform a--Pubmed
HPRDCREB binding proteinc-Maf--Pubmed
BINDCREB binding proteinv-maf musculoaponeurotic fibrosarcoma oncogene homolog isoform aCBP interacts with c-Maf. This interaction was modeled on a demonstrated interaction between CBP and c-Maf from unspecified sources.-Pubmed
HPRDE1A binding protein p300v-maf musculoaponeurotic fibrosarcoma oncogene homolog isoform a--Pubmed
HPRDE1A binding protein p300c-Maf--Pubmed
BINDE1A binding protein p300v-maf musculoaponeurotic fibrosarcoma oncogene homolog isoform ap300 interacts with c-Maf. This interaction was modeled on a demonstrated interaction between c-Maf from an unspecified source and human p300.-Pubmed
HPRDETS1v-maf musculoaponeurotic fibrosarcoma oncogene homolog isoform a--Pubmed
HPRDv-ets erythroblastosis virus E26 oncogene homolog 1c-Maf--Pubmed
HPRDc-Fosv-maf musculoaponeurotic fibrosarcoma oncogene homolog isoform a--Pubmed
HPRDv-fos FBJ murine osteosarcoma viral oncogene homologc-Maf--Pubmed

Recent Publications on MAF:

Pubmed Logo
Suppressive effects of T-412, a flavone on interleukin-4 production in T cells.
Interleukin (IL)-4 has been suggested as a molecular therapeutic target to...
3rd November, 2009
Lab of Pathology, College of Oriental Medicine, Daejeon University, Biol Pharm Bull. 2009 Nov;32(11):1875-9.
GLIDERS - A web-based search engine for genome-wide linkage disequilibrium between HapMap SNPs.
ABSTRACT: BACKGROUND: A number of tools for the examination of linkage...
3rd November, 2009
BMC Bioinformatics. 2009 Oct 31;10(1):367.
DOI Direct Link
[TRPV1 UTR-3 polymorphism and susceptibility of childhood asthma of the Han Nationality in Beijing]
OBJECTIVE: To explore TRPV1 UTR-3 polymorphism and susceptibility of...
3rd November, 2009
Institute for Environmental Health and Related Product Safety, Chinese Wei Sheng Yan Jiu. 2009 Sep;38(5):516-21.
Mutation screening of the DTNBP1 exonic sequence in 669 schizophrenics and 710 controls using high-resolution melting analysis.
A large number of independent studies have reported evidence for...
28th October, 2009
MRC Centre for Neuropsychiatric Genetics and Genomics, Department of Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 26.
DOI Direct Link
Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
There is evidence that the obesity phenotype in the Caucasian populations...
24th October, 2009
Laboratory for Endocrinology and Metabolism, Center for Genomic Medicine, J Hum Genet. 2009 Oct 23.
DOI Direct Link

View more research publications.

Press Releases on MAF:

BioPortfolio Logo
Pet Owners Honor Their Veterinarians With 'Best Vet' Nominations 7th October, 2009 Morris Animal Foundation

DENVER, Oct. 7 /PRNewswire/ -- When you love your pets, it is good to know you have a partner in improving their health and well-being: your veterinarian. That's why

Betty White Talks 'Animals' With The Grandfather of Possibilities 7th July, 2009 Morris Animal Foundation

SARASOTA, Fla., July 7 /PRNewswire/ -- Hear Betty White, star of "The Proposal," talk about her new canine kid, Pontiac, and her lifelong love of animals with the

Search for America's Best Veterinarian Continues With Third Annual 'Thank Your Vet for a Healthy Pet(R)' Contest 1st July, 2009 Morris Animal Foundation

Nationwide Essay Contest Honors Veterinarians for Dedication to Improving Animal Health and Well-Being

DENVER, July 1 /PRNewswire/ -- Nominate your veterinarian for the

Help Us Raise $1,500 in 5 Days to Improve the Health of Shelter Cats! 15th June, 2009 Happy Healthy Cat Campaign

DENVER, June 15 /PRNewswire/ -- Millions of homeless cats lose their lives in shelters each year - often due to diseases as simple as the common cold. Morris Animal Foundation's (MAF) Helping

New Health Research Will Improve Life and Health for Cats Waiting to be Adopted - June is Adopt-a-Cat Month 14th May, 2009 Morris Animal Foundation

Anonymous Cat Lover Will Match Donations to Morris Animal Foundation's Helping Shelters Help Cats Initiative Dollar for Dollar up to

BioNews Results for MAF

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BioPortfolio Logo
GE Food And Environment Regulators Need Chang
Checkbiotech:  Nov 12 2009 12:27PM Matching: maf
A genome-wide scan of 10 000 gene-centric variants and colorectal cancer risk FREE
Nature:  Nov 10 2009 10:59AM Matching: maf
A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila
Nature Chemical Biology:  Oct 7 2009 7:29PM Matching: maf
Heading Back to School: Veterinarians Combine Stethoscopes With Microscopes
Stockwatch:  Aug 31 2009 2:18PM Matching: maf
Heading Back to School: Veterinarians Combine Stethoscopes With Microscopes
Stockwatch:  Aug 31 2009 2:18PM Matching: maf
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
A Trial Assessing The Effectiveness and Safety of [S,S]-Reboxetine in Patients With Fibromyalgia

Patents:

Patents logo
US Patent No.Title
7578270 Heat activated valve system
7588368 System for diagnosing temperature sensor operation in an exhaust gas aftertreatment system
7588767 Microorganisms for therapy
7588771 Microorganisms for therapy
7588849 Solid-oxide fuel cell system having tempering of fuel cell stacks by exhaust gas

View more patents.

MAF results (if any) from reagent suppliers

Google CSE Logo
c-Maf antibody (ab55502) | Abcam
Mouse monoclonal to c-Maf . Members of the small Maf family are basic region leucine zipper (bZIP) proteins that can function as transcriptional activators
...
http://www.abcam.com/c-Maf-antibody-ab55502.html...

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Maf Antibody / Maf Antibodies
Maf Antibody / Maf Antibodies. ... Maf specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-maf.html...

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Rabbit anti-c-Maf Antibody BL662, affinity purified
internal domain of mouse v-maf musculoaponeurotic fibrosarcoma oncogene homolog C (LocusID 17132) ... Cao et al., The Protooncogene c-Maf Is an Essential ...
http://www.natutec.de/pdf_bethyl/A300-613A.pdf...

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c-Maf (M-153) Antibody sc-7866
See how others have used c-Maf (M-153): sc-7866 antibody and or c-Maf (M-153) antibody ... Western blot analysis of c-Maf expression in control (A) and ...
http://www.scbt.com/datasheet-7866-c-maf-m-153-antibody.html...

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MAFF antibody, MAFF (v-maf musculoaponeurotic fibrosarcoma ...
Buy quality rabbit MAFF antibody (interacts with human), anti-MAFF, MAFF (v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)) antibody, ...
http://www.genwaybio.com/product_info.php?products_id=43358...

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c-Maf (N-15) Antibody sc-10017
See how others have used c-Maf (N-15): sc-10017 antibody and or c-Maf (N-15) ... Differentially expressed Maf family transcription factors, c-Maf and MafA, ...
http://www.scbt.com/datasheet-10017-c-maf-n-15-antibody.html...

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c-Maf antibodies: Cell Biology > Apoptosis > Extracellular Signals ...
c-Maf antibodies. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab427 · c-Maf antibody. EMSA, WB. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=306&pt=1&c=292&ei=&mu=ra...

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