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MAGEA1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18197853 |
Multiple simultaneous detection of MAGE-A [subtypes] more specific and sensitive than detection of single MAGE-A antigen for the diagnostic and prognostic evaluation of oral squamous cell carcinoma |
| 17611652 |
Results suggest that although MAGE-A1 does not participate directly in the drug-resistant phenotype, the expression of MAGE-A1 could be a marker for the prediction of resistance to taxan-based chemotherapies in patients with gastric cancers. |
| 17634428 |
These data show, for the first time, the involvement of methyl-CpG binding domain proteins in the regulation of the MAGE-A genes. |
| 17208940 |
MAGE-A1 and NY-ESO-1 are associated with highly proliferating germ cells, whereas GAGE proteins have a more general function in germ cells unrelated to any specific developmental stage |
| 15353125 |
a novel sequence-specific DNA-protein interaction at the -30 CpG dinucleotide upstream of the gene was found having a vital part to play in the DNA methylation mediated transcription silencing of the MAGE-A1 gene |
| 12443884 |
The MAGE-A1 gene expression is not determined solely by methylation status of the promoter region in hematological malignancies. |
| 16516880 |
Detection of aberrant methylation patterns of MAGEs CpG islands using Methylation-special PCR may be useful for diagnosis of Hepatocellular Carcinoma. |
| 16497664 |
down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells |
| 14672620 |
Spontaneous in vivo priming of MAGE-specific T cell response and high frequency of MAGE1 and MAGE3 expression in hepatocellular carcinoma makes this antigen potential candidate for MAGE-specific immunotherapy in hepatocellular carcinoma. |
| 15316101 |
MAGE-A1 can function as a potent transcriptional repressor via interactions with Ski Interacting Protein and the deacetylase HDAC1. | →View more information from publications. |
Recent Publications on MAGEA1: |  |
The detection of peripheral lung cancer by MAGE A1-6 RT-nested PCR in bronchial washing specimens.
BACKGROUND: With expansion of lung cancer screening by computed tomography... | 10th September, 2009
| Department of Thoracic and Cardiovascular Surgery, Seoul National
| Lung Cancer. 2009 Aug;65(2):166-9. Epub 2009 Jan 24.
DOI Direct Link |
LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors.
Multiple clinical trials are investigating the use of the DNA methylation... | 6th August, 2009
| Department of Genitourinary Medical Oncology, University of Texas, MD
| Epigenetics. 2009 Apr;4(3):176-84. Epub 2009 Apr 6.
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CpG island methylation profiling in human melanoma cell lines.
A better understanding of key molecular changes during the pathogenesis of... | 1st August, 2009
| Department of Leukemia, The University of Texas M.D. Anderson Cancer
| Melanoma Res. 2009 Jun;19(3):146-55.
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Immunoregulatory T cells in the peripheral blood of melanoma patients treated with melanoma antigen-pulsed mature monocyte-derived dendritic cell vaccination.
BACKGROUND: Regulatory T cells (Treg) may inhibit monocyte-derived... | 20th June, 2009
| Department of Dermatology, Graduate School of Medical Science, Kyoto
| J Dermatol Sci. 2009 Apr;54(1):31-7. Epub 2009 Jan 20.
DOI Direct Link |
New insights of HLA class I association to Behcet's disease in Portuguese patients.
Human leukocyte antigen (HLA)-B*51 is a well-known genetic factor... | 19th May, 2009
| Immunogenetics Laboratory, Instituto de Ciencias Biomedicas Abel Salazar
| Tissue Antigens. 2008 Oct;72(4):379-82. Epub 2008 Jul 8.
DOI Direct Link |
→View more research publications. |
MAGEA1 results (if any) from reagent suppliers | 
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MAGE-A1 (3F256) Antibody sc-71539
MAGE-A1 shRNA (h) Lentiviral Particles, sc-37313-V, 200 µl ... Western blot analysis of MAGE-A1 expression in non-transfected: sc-110760 (A) and human ...
http://www.scbt.com/datasheet-71539-mage-a1-3f256-antibody.h...
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MAGEA1, Clone PNL2, Human mAb
Hycult biotechnology. MAGEA1, Clone PNL2, Human mAb. Description: The monoclonal antibody PNL2 recognises a melanocyte associated antigen. The ...
http://www.cellsciences.com/PDF/HM2155.pdf...
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MAGE-A1 (I-21) Antibody sc-130160
rabbit polyclonal IgG, 100µg/ml; recommended for detection of MAGE-A1 of human ... MAGE-A1 (I-21): sc-130160. Immunoperoxidase staining of formalin fixed, ...
http://www.scbt.com/datasheet-130160-mage-a1-i-21-antibody.h...
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Melanoma antigen family A 1 (MAGEA1) polyclonal antibody - Orbigen ...
KLH conjugated synthetic peptide comprised of amino acids 158 - 174 [ DVKEADPTGHSYVLVTC] of the human melanoma antigen family A 1 (MAGEA1) protein.
...
http://www.orbigen.com/commerce/catalog/product.jsp?product_...
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MAGE-A1 (h2): 293T Lysate sc-159131
Western blot analysis of MAGE-A1 expression in non-transfected: sc-117752 (A) and human MAGE-A1 transfected: sc-159131 (B) 293T whole cell lysates. ...
http://www.scbt.com/datasheet-159131-mage-a1-h2-293t-lysate....
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MAGE 1 antibody, MAGE 1 Antibody, Rabbit Polyclonal Antibody
Rabbit polyclonal to MAGE 1; MAGEA1 Melanoma Antigen Melanoma Associated Antigen MZ2-E; Melanoma-associated antigen 1, MAGA1_HUMAN. [ N/A NP_004979.3 P43355 ...
http://www.genwaybio.com/product_info.php?products_id=196518...
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MAGE-1 (MA454) Antibody sc-20033
Western blot analysis of MAGE-A1 expression in non-transfected: sc-110760 (A) and human MAGE-A1 transfected: sc-112260 (B) 293 whole cell lysates. ...
http://www.scbt.com/datasheet-20033-mage-1-ma454-antibody.ht...
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