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MAGEA12


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Gene DB Home
Symbol:MAGEA12
Name(s):melanoma antigen family A, 12
Type:protein-coding
Organism:Homo sapiens
Synonyms:MAGE12
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18197853 Multiple simultaneous detection of MAGE-A [subtypes] more specific and sensitive than detection of single MAGE-A antigen for the diagnostic and prognostic evaluation of oral squamous cell carcinoma
17634428 These data show, for the first time, the involvement of methyl-CpG binding domain proteins in the regulation of the MAGE-A genes.

Recent Publications on MAGEA12:

Pubmed Logo
Prognostic impact of cancer/testis antigen expression in advanced stage multiple myeloma patients.
This study aims to analyze the expression of 14 cancer/testis (CT)...
9th April, 2008
Discipline of Hematology and Hemotherapy, Universidade Federal de Sao Cancer Immun. 2008 Feb 1;8:2.
Expression of MAGE-A12 in oral squamous cell carcinoma.
Melanoma associated-A antigens (MAGE-A) are silent in normal tissues...
8th February, 2008
Department of Oral and Maxillofacial Surgery, Friedrich- Alexander Dis Markers. 2008;24(1):27-32.
Methyl-CpG binding domain proteins and their involvement in the regulation of the MAGE-A1, MAGE-A2, MAGE-A3, and MAGE-A12 gene promoters.
Promoter hypermethylation is responsible for the restricted expression of...
8th September, 2007
Institute of Tumor Biology, University Medical Center Hamburg-Eppendorf, Mol Cancer Res. 2007 Jul;5(7):749-59.
DOI Direct Link
Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells.
The broad range of expression of cancer-testis antigens in various tumor...
30th June, 2006
Institute of Tumor Biology, University Medical Center Hamburg-Eppendorf, Mol Cancer Res. 2006 May;4(5):339-49.
DOI Direct Link
Clinical and immunological evaluation of patients with metastatic melanoma undergoing immunization with the HLA-Cw*0702-associated epitope MAGE-A12:170-178.
Patients with metastatic melanoma who expressed HLA-Cw*0702 and whose...
20th May, 2003
Department of Transfusion Medicine, Clinical Center, National Institutes Int J Cancer. 2003 Jun 10;105(2):210-6.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Vaccine Therapy in Treating Patients With Metastatic Cancer

Patents:

Patents logo
US Patent No.Title
7488793 Isolated peptide which binds to HLA-Cw*07 and uses thereof
7419669 Peptide epitopes common to antigens of the same multigene family
7229760 mRNA amplification

MAGEA12 results (if any) from reagent suppliers

Google CSE Logo
Oncoproteins
Melanoma antigen family A 12 (MAGEA12) polyclonal antibody, PAB-10790, $175.00. melanoma antigen family A 2 (MAGEA2) polyclonal antibody, PAB-10792, $175.00 ...
http://www.orbigen.com/dictionary/cat1054.htm...

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Abgent - Chromatin and Regulation Antibodies - Chromatin_regulation
AP6160a, MAGEA10 Antibody (C-term), WB, IHC, E, H. AP6161a, MAGEA11 Antibody (N- term), WB, IHC, E, H. AP6162a, MAGEA12 Antibody (N-term), IHC, E, H ...
http://www.abgent.com/products/category/nuclear_signaling/ch...

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Oncoproteins - Orbigen Inc. - Orbigen Inc.
PAB-10790, Melanoma antigen family A 12 (MAGEA12) polyclonal antibody · NM_005367, 100 µg, $210.00. PAB-10792, melanoma antigen family A 2 (MAGEA2) ...
http://www.orbigen.com/commerce/catalog/spcategory.jsp?categ...

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MAGE (Y-18) Antibody sc-12805
Human, MAGEA12, 4111, Xq28, NM_005367 · P43365 · 300177. Human, MAGEB3, 4114, Xp21.2, NM_002365 · O15480 · 300152. Human, MAGEA2B, 266740, Xq28, NM_153488 ...
http://www.scbt.com/datasheet-12805-mage-y-18-antibody.html...

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Biomarker Discovery: Immune Response Profiling on ProtoArray ...
observed in this study, including MAGEA10 and MAGEA12, con- sistent with data obtained by ELISA (data not shown) (17). How- ever, the majority of these were
...
http://www.invitrogen.com/etc/medialib/en/filelibrary/protei...

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MAGE-A12 siRNA (h) sc-108017
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, MAGEA12, 4111, Xq28, NM_005367 ...
http://www.scbt.com/ja/datasheet-108017-mage-a12-sirna-h.htm...

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Abcam antibodies and reagents product map
... Ly6c antibodies (1) · Ly6g antibodies (10) · Lymphocytes+Langerhans cells antibodies (1) · M2A Oncofetal Antigen antibodies (1) · MAGEA12 antibodies (1)
...
http://www.abcam.com/index.html?c=251...

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