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MBD1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16284366 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17634428 |
These data show, for the first time, the involvement of methyl-CpG binding domain proteins in the regulation of the MAGE-A genes. |
| 16432238 |
PML-RARalpha functions by recruiting an HDAC3-MBD1 complex that contributes to the establishment and maintenance of the silenced chromatin state |
| 16998846 |
Sex-specific time windows for concomitant upregulation of MBD1 are associated with prenatal remethylation of the human male and female germ line. |
| 12711603 |
Suv39h1 enhanced MBD1-mediated transcriptional repression via MBD, not the C-terminal transcriptional repression domain of MBD1. MBD1 links to histone deacetylases through Suv39h1, causing methylation and deacetylation of histones for gene inactivation |
| 17428788 |
MBD1 and Polycomb group proteins have overlapping roles in epigenetic gene silencing and heterochromatin foci formation through their interactions. |
| 15327775 |
Data show that the methyl-CpG binding protein MBD1 forms a stable complex with histone H3-K9 methylase SETDB1. |
| 12770674 |
Additional evidence of variable expression in the Rett disorder phenotype is presented by a small mixed gender group of children with autistic disorder. |
| 15691849 |
These data suggest that MBD1.MCAF1.SETDB1 complex facilitates the formation of heterochromatic domains, emphasizing the role of MCAF/AM family proteins in epigenetic control, and describe a new family member, MCAF2. |
| 16757475 |
MBD1- and MCAF1-mediated heterochromatin formation involves SUMO modification | →View more information from publications. |
Recent Publications on MBD1: |  |
Specific association between the Methyl-CpG binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells.
Human telomerase reverse transcriptase (hTERT) is expressed in most cancer... | 28th October, 2008
| INSERM, U590, Lyon, F-69008, France.
| Carcinogenesis. 2008 Oct 24.
DOI Direct Link |
Structure of the sumo-interacting motif of MCAF1 bound to sumo-3.
Posttranslational modification by small ubiquitin-like modifier (SUMO)... | 10th October, 2008
| Molecular Engineering, Kyoto University, Kyoto 615-8510.
| J Biol Chem. 2008 Oct 7.
DOI Direct Link |
Proteomic analysis of differential proteins in pancreatic carcinomas: Effects of MBD1 knock-down by stable RNA interference.
BACKGROUND: Methyl-CpG binding domain protein 1 (MBD1), a suppressor of... | 10th October, 2008
| Pancreatic Disease Institute, Department of General Surgery, Huashan
| BMC Cancer. 2008 Apr 29;8:121.
DOI Direct Link |
Evolution of DNA-methylation machinery: DNA methyltransferases and methyl-DNA binding proteins in the amphioxus Branchiostoma floridae.
DNA methylation is an epigenetic mark associated with gene regulation and... | 25th September, 2008
| Departament de Genetica, Facultat de Biologia, Universitat de Barcelona,
| Dev Genes Evol. 2008 Sep 24.
DOI Direct Link |
Aurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer.
BACKGROUND: Analysis of biopsies from a recent clinical trial suggested... | 19th August, 2008
| Department of Pathology, Institute of Basic Medical Sciences, Beijing,
| Cancer Biol Ther. 2008 Sep;7(9):1388-97. Epub 2008 Sep 2.
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→View more research publications. |
MBD1 results (if any) from reagent suppliers |
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MBD1 methyl-CpG binding domain protein 1
WH0004152M2, Monoclonal Anti-MBD1 antibody produced in mouse clone 2C7, purified immunoglobulin, buffered aqueous solution, human ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...
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MBD1 Antibody (C-term)
Abgent develops powerful tools to profile posttranslational modifications related to cellular function and disease. Abgent antibodies target protein kinases ...
http://www.abgent.com/catalog_no/AP1036b...
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MBD1 (G-18) Antibody sc-9395
See how others have used MBD1 (G-18): sc-9395 and or MBD1 (G-18) antibody conjugates. Chadwick B.P. et al. 2002. Cell cycle–dependent localization of ...
http://www.scbt.com/datasheet-9395-mbd1-g-18-antibody.html...
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M6569 Anti MBD1 antibody produced in rabbit ~1 mg/mL, affinity ...
M6569 Anti-MBD1 antibody produced in rabbit ~1 mg/mL, affinity isolated antibody , buffered aqueous solution.
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...
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MBD1 (M-254) Antibody sc-10751
Mbd1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding ... MBD1 (M-254): sc-10751. Western blot analysis of MBD1 expression in ...
http://www.scbt.com/datasheet-10751-mbd1-m-254-antibody.html...
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MBD1 Antibody (N-term)
Western blot analysis of anti-MBD1 Pab (Cat. #AP1036a) in Jurkat cell lysate. MBD1 (Arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was ...
http://www.abgent.com/products/catalog_no/AP1036a...
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Anti-MBD1 Produced in rabbit, Affinity isolated antibody Product ...
MBD1 isoforms. The antibody is affinity-purified using. the immunizing peptide immobilized on ... MBD1 can act as a transcriptional repressor. The way it ...
http://www.sigmaaldrich.com/sigma/datasheet/M6569dat.pdf...
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MBD1 antibody - ChIP Grade (ab3753) reviews | Abcam
Rabbit polyclonal to MBD1 - ChIP Grade. DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper ...
http://www.abcam.com/index.html?pageconfig=reviews&intAbID=3...
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MBD1 siRNA (m) sc-35864
Recommended Control Antibody (click catalog # for product information). Product Name, Catalog #, Unit, Price, Qty, Wish List. MBD1 (B-5), sc-25261 ...
http://www.scbt.com/datasheet-35864-mbd1-sirna-m.html...
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MBD1 antibodies | Abcam
MBD1 antibodies. ... MBD1 antibody [100B272.1.] - ChIP Grade. WB, ChIP. Images · Specific publication references. Mouse monoclonal ...
http://www.abcam.com/index.html?t=10843&pt=1&c=558...
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