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ME1


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Gene DB Home
Symbol:ME1
Name(s):malic enzyme 1, NADP(+)-dependent, cytosolic
Type:protein-coding
Organism:Homo sapiens
Synonyms:HUMNDME, MES
Links: Pubmed, Entrez Gene, GeneCards, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11352855 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16757477 that the single mutation of Gln362 to Lys in human m-NAD-ME changes it to an NADP+-dependent enzyme, which is characteristic because it is non-allosteric, non-cooperative, and NADP+-specific

Recent Publications on ME1:

Pubmed Logo
Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks.
A principal task in dissecting the genetics of complex traits is to...
15th May, 2009
Department of Medicine, David Geffen School of Medicine, University of Nat Genet. 2009 Apr;41(4):415-23. Epub 2009 Mar 8.
DOI Direct Link
Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion.
Pyruvate cycling has been implicated in glucose-stimulated insulin...
19th March, 2009
BioCurrents Research Center, Marine Biological Laboratory, 7 MBL St., Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1354-62. Epub 2009 Mar 17.
DOI Direct Link
Cloning and functional characterization of the ovine malic enzyme promoter.
While in human and rodents lipogenesis occurs predominantly in the liver,...
12th February, 2009
Department of Animal Science, Laboratory of Animal Breeding and Husbandry, Gene. 2009 Jan 1;428(1-2):36-40. Epub 2008 Oct 8.
DOI Direct Link
Mixtures of plant growth-promoting rhizobacteria enhance biological control of multiple cucumber pathogens.
ABSTRACT Plant growth-promoting rhizobacteria (PGPR) strains INR7...
24th October, 2008
Phytopathology. 1998 Nov;88(11):1158-64.
DOI Direct Link
Translation Inhibition of Capped and Uncapped Viral RNAs Mediated by Ribosome-Inactivating Proteins.
ABSTRACT Ribosome-inactivating proteins (RIPs) are N-glycosidases that...
24th October, 2008
Phytopathology. 2003 May;93(5):588-95.
DOI Direct Link

View more research publications.

Clinical Trials:

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Monoclonal Antibody Therapy in Treating Patients With Brain Metastases

Patents:

Patents logo
US Patent No.Title
7330463 Enterprise voice over internet protocol (VoIP) virtual private network (VPN)
7411858 Dual-plane type flash memory device having random program function and program operation method thereof
7412031 Radiation imaging apparatus, radiation imaging system and radiation imaging method
7413059 Fire control system for elevator
7415358 Molecular toxicology modeling

View more patents.

ME1 results (if any) from reagent suppliers

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