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ME1


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Symbol:ME1
Name(s):malic enzyme 1, NADP(+)-dependent, cytosolic
Type:protein-coding
Organism:Homo sapiens
Synonyms:HUMNDME, MES
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11352855 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16757477 that the single mutation of Gln362 to Lys in human m-NAD-ME changes it to an NADP+-dependent enzyme, which is characteristic because it is non-allosteric, non-cooperative, and NADP+-specific

Recent Publications on ME1:

Pubmed Logo
Chronic reduction of the cytosolic or NAD(P)-mitochondrial malic enzyme does not affect insulin secretion in a rat insulinoma cell line.
The cytosolic malic enzyme (ME1) has been suggested to augment insulin...
28th October, 2009
University of Wisconsin School of Medicine and Public Health, United J Biol Chem. 2009 Oct 26.
DOI Direct Link
Identification of domains involved in the allosteric regulation of cytosolic Arabidopsis thaliana NADP-malic enzymes.
The Arabidopsis thaliana genome contains four genes encoding NADP-malic...
23rd October, 2009
Centro de Estudios Fotosinteticos y Bioquimicos, Universidad Nacional de FEBS J. 2009 Oct;276(19):5665-77. Epub 2009 Sep 2.
DOI Direct Link
Tumor necrosis factor-alpha and interleukin-1 antagonists alleviate inflammatory skin changes associated with epidermal growth factor receptor antibody therapy in mice.
Cancer patients receiving epidermal growth factor receptor (EGFR) antibody...
26th September, 2009
Research Division, ImClone Systems, a wholly-owned subsidiary of Eli Lilly Cancer Res. 2009 Jul 15;69(14):5643-7. Epub 2009 Jul 7.
DOI Direct Link
Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells.
Despite interest in malic enzyme(ME)s in insulin cells, mitochondrial...
11th September, 2009
Childrens Diabetes Center, University of Wisconsin School of Medicine and Arch Biochem Biophys. 2009 Aug 15;488(2):100-4.
[Developmental expression changes of specific genes in adipose tissue for different pig breeds by using pathway-focused microarray]
The expression changes of genes associated with adipose metabolism and...
9th September, 2009
College of Animal Science and Technology, Sichuan Agricultural University, Sheng Wu Gong Cheng Xue Bao. 2008 Apr;24(4):665-72.

View more research publications.

Clinical Trials:

Clinical Trials Logo
Monoclonal Antibody Therapy in Treating Patients With Brain Metastases

Patents:

Patents logo
US Patent No.Title
7402312 Antibodies to vascular endothelial growth factor 2 (VEGF-2)
7458088 Intermediate for optical recording medium and method of manufacturing the optical recording medium
7459987 Electrical adaption network with a transformation line
7461723 Fire control system of elevator
7469896 Sheet stacking apparatus and image forming system equipped therewith

View more patents.

ME1 results (if any) from reagent suppliers

Google CSE Logo
ME1 antibody (ab55537) | Abcam
Mouse monoclonal to ME1. This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme,
...
http://www.abcam.com/ME1-antibody-ab55537.html...

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ME1 (99.1) Antibody sc-100569
mouse monoclonal IgG1, 100 µg/ml; raised against recombinant ME1 of human ... ME1 (99.1): sc-100569. Western blot analysis of ME1 expression in HepG2 whole
...
http://www.scbt.com/datasheet-100569-me1-99-1-antibody.html...

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ME1 monoclonal antibody (M03)
Abgent develops powerful tools to profile posttranslational modifications related to cellular function and disease. Abgent antibodies target protein
kinases ...
http://www.abgent.com/products/catalog_no/AT2830a_ME1_monocl...

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ME1 Antibody / ME1 Antibodies
ME1 Antibody / ME1 Antibodies. ... ME1 specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-me1.html...

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ME1 antibodies: Cell Biology > Other Antibodies > Oxidative Stress ...
ME1 antibodies. ... Image Abreview Publication. ab55537 · ME1 antibody. WB. Images · Specific publication references. Mouse monoclonal ...
http://www.abcam.com/index.html?t=227362&pt=1&c=3642&ei=&mu=...

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ME1 Antibody / ME1 Antibodies
ME1 Antibody / ME1 Antibodies. ... ME1 specific siRNA, sHRNA Plasmid과 shRNA Lentiviral Particles gene silencers 도 제공합니다. ...
http://www.scbt.com/ko/table-me1.html...

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p53 (mono methyl K372) antibody (ab16033) | Abcam
Western blots were blocked in PBS with 2% non-fat milk for 2 hrs following the overnight incubation with p53-K372 me1-specific antibody (1:5000 and 5 ug of ...
http://www.abcam.com/p53-mono-methyl-k372-antibody-ab16033.h...

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