Friday November 27 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

MEIS1


Suggest Content
Advertise Here
Gene DB Home
Symbol:MEIS1
Name(s):Meis homeobox 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC43380
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17805329 In CREB-overexpressing control cells, Meis1 RNA expression was 3-fold higher than in untransfected cells. In AML cells, it was 5- to 10-fold higher than in the control cells. Persistent Meis1 expression may cause leukemia.
17637780 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
18216367 MEIS1 polymorphism is associated with Nocturnal Myoclonus Syndrome.
16172981 pre B-cell leukemia transcription factor 1 is mostly cytoplasmic in epithelial endometrial cells of the developing female genital tract despite the nuclear localization of MEIS1
12609849 these studies demonstrate that the homeodomain proteins, MEIS1, PBX1B, and PBX2, play an important role in megakaryocytic gene expression
14701735 Hoxa9 and Hoxa7 as well as the Hox coregulators Meis1 and Pbx3 among the targets upregulated by MLL-ENL-ERtm in conditionally transformed cells
15681849 CYBB is a common target gene repressed by HoxA10 and activated by HoxA9, and Meis1 and Nup98-hoxA9 have roles in repressing myeloid-specific gene transcription
14966272 Data report novel nucleoporin 98 fusions with homeobox (HOX)A10, HOXB3 and HOXB4, and describe the results of coexpression of these proteins with the Hox cofactor Meis1 in leukemic induction.
15103390 found a constant downregulation of the Meis 1 gene mRNA in AML1-ETO acute myeloid leukemias and in those cases harboring in frame mutations in the bZIP domain of CEBPalpha
15479723 advantage to Meis1-HoxA9 coexpressing cells in vivo, leading to leukemogenesis.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDHOX A7Meis homeobox 1--Pubmed
HPRDhomeo box A7Homeobox protein Meis1--Pubmed
HPRDHOXA10Meis homeobox 1--Pubmed
HPRDhomeobox A10 isoform aHomeobox protein Meis1--Pubmed
HPRDHOX B1Meis homeobox 1--Pubmed
HPRDhomeo box B1Homeobox protein Meis1--Pubmed
HPRDHOX D11Meis homeobox 1--Pubmed
HPRDhomeobox D11Homeobox protein Meis1--Pubmed
HPRDHomeo box D12Meis homeobox 1--Pubmed
HPRDhomeobox D12Homeobox protein Meis1--Pubmed

Recent Publications on MEIS1:

Pubmed Logo
Association of intronic variants of the BTBD9 gene with Tourette syndrome.
OBJECTIVE: To test the association between Tourette syndrome (TS) and...
31st October, 2009
Sainte Justine Hospital Research Center and the Center of Excellence in Arch Neurol. 2009 Oct;66(10):1267-72.
DOI Direct Link
Establishment of canine hemangiosarcoma xenograft models expressing endothelial growth factors, their receptors, and angiogenesis-associated homeobox genes.
BACKGROUND: Human hemangiosarcoma (HSA) tends to have a poor prognosis;...
15th October, 2009
Laboratory of Veterinary Pathology, Department of Veterinary Medicine, BMC Cancer. 2009 Oct 14;9:363.
DOI Direct Link
PBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter region.
Sox3/SOX3 is considered to be one of the earliest neural markers in...
6th October, 2009
Biochem J. 2009 Oct 2.
DOI Direct Link
Replication of restless legs syndrome loci in three European populations.
BACKGROUND: Restless legs syndrome (RLS) is associated with common...
26th September, 2009
Helmholtz Zentrum Munich, National Research Center of Environment and J Med Genet. 2009 May;46(5):315-8. Epub 2009 Mar 10.
DOI Direct Link
Immunohistochemical demonstration of angiogenesis-associated homeobox proteins in canine vascular tumours.
Angiogenic homeobox genes regulate the behaviour of endothelial cells...
23rd September, 2009
Laboratory of Veterinary Pathology, Department of Veterinary Medicine, J Comp Pathol. 2009 Aug-Oct;141(2-3):199-203. Epub 2009 Jun 7.
DOI Direct Link

View more research publications.

BioNews Results for MEIS1

: RSS Logo
BioPortfolio Logo
AnaSpec introduces Z-Fish antibodies for cell cycle control research
PharmaBiz:  Aug 17 2009 8:04AM Matching: meis1

Patents:

Patents logo
US Patent No.Title
7595159 Prediction of Parkinson's disease using gene expression levels of peripheral blood samples
7348142 Cancer diagnostic panel
7332290 Dectection of AMACR cancer markers in urine
7265263 Potato transcription factors, methods of use thereof, and a method for enhancing tuber development
7229774 Expression profile of prostate cancer

View more patents.

MEIS1 results (if any) from reagent suppliers

Google CSE Logo
MEIS1 antibody (ab19867) | Abcam
Rabbit polyclonal to MEIS1. MEIS1 is a member of the TALE (three amino acid loop extension) family of homeodomain containing proteins.
http://www.abcam.com/meis1-antibody-ab19867.html...

Thumbshot
Meis1/2 (C-17) Antibody sc-10599
See how others have used Meis1/2 (C-17): sc-10599 antibody and or Meis1/2 (C-17) ... HOXA10, Pbx2, and Meis1 protein expression in the human endometrium: ...
http://www.scbt.com/datasheet-10599-meis1-2-c-17-antibody.ht...

Thumbshot
MEIS1 Antibody MEIS1
MEIS1 antibody was raised against a synthetic peptide of MEIS1.,
http://www.prosci-inc.com/shop/catalog1/MEIS1-Antibody-p-276...

Thumbshot
Meis1/2 (N-17) Antibody sc-10596
See how others have used Meis1/2 (N-17): sc-10596 antibody and or Meis1/2 (N-17) ... Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific ...
http://www.scbt.com/datasheet-10596-meis1-2-n-17-antibody.ht...

Thumbshot
MEIS1 antibodies: Stem Cells > Hematopoietic Progenitors > Myeloid ...
MEIS1 antibodies. ... MEIS1 antibody. WB, ELISA. Images. Goat polyclonal. Reacts with: Hu. Predicted: Ms, Rat, Cow. Terms and conditions · Legal ...
http://www.abcam.com/index.html?t=111492&pt=1&c=4508&ei=&mu=...

Thumbshot
Meis1/2 (H-80) Antibody sc-25412
rabbit polyclonal IgG, 200 µg/ml; epitope corresponding to amino acids 1-80 mapping at the N-terminus of Meis1 of human origin; recommended for detection of
...
http://www.scbt.com/datasheet-25412-meis1-2-h-80-antibody.ht...

Thumbshot
MB-MN
SAB2500627, Anti-MEIS1 antibody produced in goat New, (polyclonal) ... human ... MEIS1(4211), human, mouse, bovine, rat, ELISA (i), WB, pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

Thumbshot

Search Bioportfolio and other Life Science Sites for MEIS1, or search for MEIS1 on BioPortfolio's antibody search engine.
This page has been viewed 176 times
Recent Search Terms used to find this page:
MEIS1 HOXA9 | target Meis1 | genecards MEIS | creb meis1 | Meis homeobox 1 | meis b cell | meis1 tale | meis homeobox | Meis homeobox human antibody | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.