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Gene DB Home
Symbol:H
Name(s):Hairless
Type:protein-coding
Organism:Drosophila melanogaster
Synonyms:CG5460
Links: Pubmed, Entrez Gene, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12154126 Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless. H directly binds two corepressor proteins, Groucho (Gro) and dCtBP.
12422020 Two isoforms of the Notch antagonist Hairless are produced by differential translation initiation. The presence of either isoform throughout the cell cycle allows efficient inhibition of Notch-regulated cell proliferation.
16410550 Data show that Pros26.4 negatively regulates Hairless at the genetic and molecular level, providing a novel mechanism of positive regulation of Notch signalling.
12124948 modifiers of the rough eye phenotype resulting from overexpression of the Notch antagonist hairless in Drosophila
16287856 Hairless has a second mode of repression that antagonizes Notch intracellular domain and is independent of Gro or CtBP binding.
17362357 Hairless is a central component of the regulation of the Notch signalling pathway in Drosophila, and is hence essential for cell differentiation and tissue development in the fly.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDC-terminal Binding Protein CG7583-PA, isoform A [Drosophila melanogaster].Hairless CG5460-PA, isoform A [Drosophila melanogaster].Hairless interacts with dCtBP.-Pubmed
BINDHairless CG5460-PA, isoform A [Drosophila melanogaster].groucho CG8384-PA, isoform A [Drosophila melanogaster].Hairless interacts with Groucho.-Pubmed

H results (if any) from reagent suppliers

Google CSE Logo
Index-H of SPI Supplies Catalog
H. Half Grids for FIB and Ion Milling. Beryllium · Molybdenum. Hand Care. Cleaner; Conditioner · Cream. Hand Held. Magnifying Glasses ...
http://www.2spi.com/catalog/index/h.html...

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Browse By Molecule < H > - R&D Systems
Select a Letter: 0-9 | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z. Browse By Molecule < H >. H60 ...
http://www.rndsystems.com/molecule_letter.aspx?l=H...

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The Edward H. Birkenmeier Distinguished Lectureship in Genetics ...
Edward H. Birkenmeier, 1947-1996, was a member of the scientific staff of The Jackson Laboratory for sixteen years and a Senior Staff Scientist for five.
http://www.jax.org/events/birk/index.html...

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Cayman Chemical | Home
Cayman's H-PGDS FP-Based Inhibitor Screening Assay Kit - Green provides a rapid, accurate assay for screening H-PGDS inhibitors. In this assay, a H-PGDS ...
http://www.caymanchem.com/...

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Hycult biotechnology bv
Complement factor H (CFH) is the major fluid-phase regulator of the alternative pathway of ... HK353 factor H, Human, H402 and Y402 variant detection, ELISA ...
http://www.hbt.nl/...

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Antibodies for Paraffin Tissue Staining- Santa Cruz Biotechnology ...
Bad (C-7), sc-8044, mouse IgG1, FL (h), WB, IP, IF, IHC(P), ELISA, m, r, h .... caspase-7 p20 (B-5), sc-28295, mouse IgG1, N-terminus (h), WB, IP, IF, ...
http://www.scbt.com/antibodies_for_paraffin_tissue_staining....

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Products, Restriction Endonucleases, NEB
High Fidelity (HF) Restriction Enzymes. Synthetic Biology. Other. Restriction Endonucleases A | B | C | D | E | F | H | K | M | N | P | R | S | T | X | Z ...
http://www.neb.com/nebecomm/products/category1.asp...

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