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KITLG
| Symbol: | KITLG | | Name(s): | KIT ligand | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | DKFZp686F2250, KL-1, Kitl, MGF, SCF, SF, SHEP7 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16905672 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18083106 |
These experiments suggest that regulatory changes in Kitlg contribute to natural variation in vertebrate pigmentation, and that similar genetic mechanisms may underlie rapid evolutionary change in fish and humans. |
| 17855052 |
Early myeloid cells expressing GNNK+ or GNNK-c-KIT show different responses to stem cell factor. |
| 17556598 |
Distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis. |
| 17687495 |
SCF can be introduced to rescue cells from the damage caused by certain antineoplastic agents. |
| 17410437 |
SCF-enhanced proliferation and invasion of KIT-positive colorectal cancer cells is achieved mainly through the PI3K/Akt pathway. |
| 12297464 |
SCF mRNA is present in K562, HL-60 and CML cells in blast phase |
| 16780589 |
SCF and Kit are expressed in bronchial biopsies from lung transplant recipients irrespective of the clinical status of the graft; role for these factors in tissue repair following lung transplantation is hypothesised |
| 16709604 |
stem cell factor and clusterin may have roles in azoospermia |
| 15576295 |
The SCF is a member of a group of glycoproteins called hematopoietic cytokines (HCs). | →View more information from publications. |
Recent Publications on KITLG: |  |
Association study between keratinocyte-derived growth factor gene polymorphisms and susceptibility to vitiligo vulgaris in a Taiwanese population: potential involvement of stem cell factor.
BACKGROUND: Vitiligo vulgaris is a depigmentary disorder resulting from... | 3rd November, 2009
| Department of Dermatology, Kaohsiung Medical University Hospital,
| Br J Dermatol. 2009 Jun;160(6):1180-7. Epub 2009 Mar 13.
DOI Direct Link |
Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.
Acquired uniparental disomy (aUPD) is a common feature of cancer genomes,... | 15th September, 2009
| Cancer Genomics Project, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku,
| Nature. 2009 Aug 13;460(7257):904-8. Epub 2009 Jul 20.
DOI Direct Link |
High marks for GWAS.
Two genome-wide association studies for testicular cancer report... | 18th July, 2009
| Division of Cancer Epidemiology and Genetics, National Cancer Institute,
| Nat Genet. 2009 Jul;41(7):765-6.
DOI Direct Link |
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.
Testicular germ cell tumors (TGCT) have been expected to have a strong... | 18th July, 2009
| Department of Biostatistics and Epidemiology, University of Pennsylvania
| Nat Genet. 2009 Jul;41(7):811-5. Epub 2009 May 31.
DOI Direct Link |
A genome-wide association study of testicular germ cell tumor.
We conducted a genome-wide association study for testicular germ cell... | 18th July, 2009
| Section of Cancer Genetics, Institute of Cancer Research, Sutton, Surrey,
| Nat Genet. 2009 Jul;41(7):807-10. Epub 2009 May 31.
DOI Direct Link |
→View more research publications. |
KITLG results (if any) from reagent suppliers | 
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SCF (KITLG) Antibody (C-term)
Immunofluorescence analysis of anti-KITLG Antibody (C-term) (Cat.#AP1484b) in HeLa cells. 0.025 mg/ml primary antibody was followed by ...
http://www.abgent.com/products/catalog_no/AP1484b...
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KITLG antibody, Rabbit anti Human SCF Antibody, Rabbit Polyclonal ...
Buy quality rabbit KITLG antibody (interacts with n/a), anti-KITLG, Rabbit anti Human SCF antibody, rabbit polyclonal antibody, Rabbit anti Human SCF ...
http://www.genwaybio.com/product_info.php?products_id=244644...
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SCF (KITLG) Antibody (N-term)
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with KITLG antibody (N-term) (Cat.#AP1484a), which was peroxidase-conjugated to ...
http://www.abgent.com/products/catalog_no/AP1484a_SCF_KITLG_...
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Platelet Derived Growth Factor Receptor (PDGFR)
affinity isolated antibody, human ... KITLG(4254), human, ELISA (i), Neutral, WB , pricing ... human ... KITLG(4254), human, FACS, Neutral, pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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SCF Antibody Stem cell factor
Additional Names. SCF, Stem cell factor, Mast cell growth factor, MGF, c-kit ligand, KL-1, KITLG, SHEP7. SCF Antibody. Description ...
http://www.prosci-inc.com/shop/catalog1/SCF-Antibody-p-6900....
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Abgent - Stem Cell
Application validated by third-party citation. Stem Cell Antibodies. stem cell. Featured Antibodies: AC133 Monoclonal · KITLG · AC133 Polyclonal · NANOG ...
http://www.abgent.com/products/category/stem_cell...
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SCF (G-3) Antibody sc-13126
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, KITLG, 4254, 12q21.32, NM_000899, ...
http://www.scbt.com/datasheet-13126-scf-g-3-antibody.html...
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