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E2f


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Symbol:E2f
Name(s):E2F transcription factor
Type:protein-coding
Organism:Drosophila melanogaster
Synonyms:CG6376, DRTF1/E2F, DmE2F-1, E(Sev-CycE)3A, E(var)3-93E, E(var)3-95E, E(var)93E, E2F-1, E2F1, Evar(3)164, dE2F, dE2F1, def21, drosE2F1, l(3)07172, l(3)j3B1, l(3)j3C2, l(3)rM729
Links: Pubmed, Entrez Gene, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17923695 In addition to de2f2, the loss of a DEAD box protein Belle (Bel) also rescues proliferation of de2f1 mutant cells.
17676643 PP1 is not a major regulator of the Rbf1/E2F1 pathway in Drosophila
12651890 cells containing dE2F2 require dE2F1 to either prevent, or reverse, dE2F-mediated repression
12881421 role in endoreplication during Drosophila development
12234932 RBF1 and RBF2 interact with different subsets of E2F proteins; this enables the RBF proteins to regulate E2F-dependent transcription in distinct ways
17419999 We examined the process of cell cycle exit in Drosophila wings and eyes and discovered that cell cycle exit can be prevented or even reversed in terminally differentiating cells by the simultaneous activation of E2F1 and either CycE/cdk2 or CycD/cdc4.
15479636 Results describe the purification of E2F transcription factor/retinoblastoma tumor suppressor protein repressor complexes from Drosophila embryo extracts and characterize their roles in E2F regulation.
12466526 The caudal homeodomain protein activates Drosophila E2F gene expression.
17112319 Apoptosis inhibitor-5/antiapoptosis clone-11 (Api5/Aac11) is a critical determinant of dE2F1-induced apoptosis in vivo and in vitro.
12464435 dE2F1 has a role in nurse cell apoptosis

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDRetinoblastoma-family protein CG7413-PA [Drosophila melanogaster].E2F transcription factor CG6376-PA, isoform A [Drosophila melanogaster].dE2F interacts with RBF.-Pubmed
BINDDP transcription factor CG4654-PA, isoform A [Drosophila melanogaster].E2F transcription factor CG6376-PA, isoform A [Drosophila melanogaster].dE2F interacts with dDP.-Pubmed

E2f results (if any) from reagent suppliers

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E2F Antibody / E2F Antibodies
E2F Antibody / E2F Antibodies. ... E2F specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-e2f.html...

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E2F-1 Antibody #3742
The E2F transcription factors are essential for regulation of the cell cycle (1, 2). Physiological E2F is a heterodimer composed of an E2F subunit together ...
http://www.cellsignal.com/products/3742.html...

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E2F-1 (KH95) Antibody sc-251
Suitable for use as control antibody for E2F-1 siRNA (h): sc-29297 and ... E2F-1 (KH95) X TransCruz antibody is recommended for Gel Supershift and ChIP ...
http://www.scbt.com/datasheet-251-e2f-1-kh95-antibody.html...

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E2F-1 Monoclonal Antibody Anti-E2F-1
E2F-1 monoclonal antibody can be stored at 4˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. ...
http://www.prosci-inc.com/shop/catalog1/E2F-1-Monoclonal-Ant...

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E2F-2 (TFE-25) Antibody sc-9967
See how others have used E2F-2 (TFE-25): sc-9967 antibody and or E2F-2 (TFE-25) ... E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in ...
http://www.scbt.com/datasheet-9967-e2f-2-tfe-25-antibody.htm...

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E2F-1 Antibody
20 Jul 2005 ... Background: The E2F transcription factors are essen- ... endogenous levels of total E2F-1 protein. The antibody ...
http://www.cellsignal.com/pdf/3742.pdf...

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E2F-4 (RK-13) Antibody sc-511
See how others have used E2F-4 (RK-13): sc-511 antibody and or E2F-4 (RK-13) ... Western blot analysis of E2F-4 expression in non-transfected: sc-117752 (A) ...
http://www.scbt.com/datasheet-511-e2f-4-rk-13-antibody.html...

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