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hh
| Symbol: | hh | | Name(s): | hedgehog | | Type: | protein-coding | | Organism: | Drosophila melanogaster | | Synonyms: | CG4637, HH, Mir, Mrt, anon-WO0134654.19, anon-WO0182946.19, bar, bar-3, bar3, hg, l(3)hh, l(3)neo56, l(3)neo57 | | Links: |
Pubmed,
Entrez Gene,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18198278 |
lipophorins internalization does not play a major role in Hedgehog (Hh) signal transduction but does in Hh gradient formation |
| 17881487 |
Data suggest that, after activation of Smoothened, the Fused kinase induces a conformational change in Costal2 that allows the disassembly of the Smo-Fu-Cos2-Cubitus interruptus complex and consequent activation of Hedgehog target genes. |
| 17981140 |
ectopically activating Hh signaling in fly epithelia reveals a direct relationship between the duration of exposure to this signaling pathway, the accumulation of activated Myosin II, and the degree of tissue invagination. |
| 17559828 |
Cul3 downregulates Ci levels to modulate Hh signaling activity, thus ensuring proper cell proliferation during retinal development. |
| 17573067 |
dysfunction of omb elicits hyperactivation of Hh signaling that causes an ectopic folding and local overgrowth in the wing columnar epithelium |
| 11959822 |
Inductive patterning of the embryonic brain in Drosophila. The loss of Hedgehog expressed in the foregut appears to mediate this effect, as it does in vertebrates. |
| 12015606 |
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E. |
| 12954721 |
Results describe the relationships between Delta, Hedgehog, and Decapentaplegic signaling pathways during Drosophila eye development. |
| 14602684 |
Signalling properties of this molecule in the embryonic epidermis are examined. |
| 12782270 |
Hh has a role in vein positioning in the Drosophila wing | →View more information from publications. |
hh results (if any) from reagent suppliers | 
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L7016 Monoclonal Anti-LDH (H-Subunit) antibody produced in mouse ...
clone HH-17, ascites fluid. Printable Reviews ... clone, HH-17 (monoclonal). contains, 15 mM sodium azide. species reactivity, human ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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Shh Antibody #2287
Hedgehog proteins (Hh) are secreted signaling proteins that play many roles ... The three identified vertebrate Hh genes are Sonic (Shh), Indian (Ihh) and ...
http://www.cellsignal.com/products/2287.html...
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8. Choi,Y.H., Kim,K.B., Kim,H.H., Hong,G.S., Kwon,Y.K.,
Choi,Y.H., Kim,K.B., Kim,H.H., Hong,G.S., Kwon,Y.K.,. Chung,C.W., Park,Y.M., Shen,Z.J., Kim,B.J., Lee,S.Y. and. Jung,Y.K. (2001) FLASH coordinates NF-kappa
...
http://www.hypromatrix.com/Products/Primary_Antibody/FLASH.p...
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Shh Antibody
covalently attached to the carboxy terminus of Hh-N and then Hh-N is further modified by acetylation at its amino terminus. This dual modified Hh-N is ...
http://www.cellsignal.com/pdf/2287.pdf...
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Hedgehog [Hh] Signalling Pathway
Blocks the GLI function which constitutes the final step in the Hh pathway. Interferes with GLI1 DNA binding in living cells. ...
http://www.scbt.com/chemicals-table-hedgehog_hh_signalling_p...
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Shh/Ihh Antibody
and aberrant Hh signaling activity is associated with numer- ous birth defects. ... There are three Hh genes in vertebrates: Sonic (Shh), ...
http://www.cellsignal.com/pdf/2271.pdf...
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Hh Signaling Antagonist VII, JK184 sc-202649
Shown to exhibit ≥100-fold greater cytotoxicity towards five Hh activated tumor cells (GI50 ≤21 nM vs. 1.6 µM for the non-Hh activated H3H10T1/2 cells) in ...
http://www.scbt.com/datasheet-202649.html...
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