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ACHE


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Symbol:ACHE
Name(s):acetylcholinesterase (Yt blood group)
Type:protein-coding
Organism:Homo sapiens
Synonyms:ARACHE, N-ACHE, YT
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12928915 Observational study of gene-disease association. (HuGE Navigator)
15060281 Observational study of gene-disease association. (HuGE Navigator)
15459952 Observational study of genotype prevalence. (HuGE Navigator)
15690550 Observational study of gene-disease association. (HuGE Navigator)
15715671 Observational study of gene-gene interaction. (HuGE Navigator)
15783300 Observational study of genotype prevalence. (HuGE Navigator)
15974920 Observational study of genotype prevalence. (HuGE Navigator)
17503475 Observational study of gene-disease association. (HuGE Navigator)
18161504 Testing potency of acetylcholinesterase reactivators.
17948252 These findings suggest that cell surface AChE, possibly in a novel signalling complex containing APP and perlecan, contributes to a generalised mechanism for polarised membrane protrusion and migration in all adherent cells.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDAcetylcholinesteraseamyloid beta A4 protein precursor, isoform a--Pubmed
HPRDAcetylcholinesterasealpha 1 type IV collagen preproprotein--Pubmed
HPRDAcetylcholinesteraselaminin, alpha 1 precursor--Pubmed
HPRDAcetylcholinesteraseacetylcholinesterase collagen-like tail subunit isoform I precursor--Pubmed
HPRDAcetylcholinesteraseligatin--Pubmed
HPRDAcetylcholinesteraseproline rich membrane anchor 1--Pubmed
HPRDacetylcholinesterase isoform E4-E5 precursorLigatin--Pubmed
HPRDacetylcholinesterase isoform E4-E5 precursorProline rich membrane anchor 1--Pubmed
HPRDacetylcholinesterase isoform E4-E5 precursorAmyloid beta A4 protein--Pubmed
HPRDacetylcholinesterase isoform E4-E5 precursorCollagen, type IV, alpha 1--Pubmed

Recent Publications on ACHE:

Pubmed Logo
Analytical approaches to investigate protein-pesticide adducts.
Organophosphorus pesticides primarily elicit toxicity via their common...
3rd November, 2009
School of Biomedical Sciences, University of Nottingham, Queen's Medical J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Oct 22.
DOI Direct Link
Structural aspects of flavonoids as inhibitors of human butyrylcholinesterase.
Selected flavonoids: galangin, kaempferol, quercetin, myricetin, fisetin,...
3rd November, 2009
Institute for Medical Research and Occupational Health, Ksaverska cesta 2, Eur J Med Chem. 2009 Oct 6.
DOI Direct Link
DNA damage in horticultural farmers: a pilot study showing an association with organophosphate pesticide exposure.
A study of horticultural farmers exposed to organophosphate pesticides...
30th October, 2009
Institute for Research on Environment and Sustainability, Newcastle Biomarkers. 2009 Nov;14(7):443-51.
DOI Direct Link
In vivo evaluation of N-[(18)F]fluoroethylpiperidin-4ylmethyl acetate in rats compared with MP4A as a probe for measuring cerebral acetylcholinesterase activity.
[(11)C]MP4A is an established radioprobe for quantification of cerebral...
29th October, 2009
Molecular Probe Group, Molecular Imaging Center, National Institute of Synapse. 2009 Oct 26;64(3):209-215.
DOI Direct Link
Effects of Cholinesterase Inhibitors on the Activities and Protein Levels of Cholinesterases in the Cerebrospinal Fluid of Patients with Alzheimer's Disease: A Review of Recent Clinical Studies.
Alzheimer's disease (AD) is a progressive neurodegenerative disease...
29th October, 2009
Department of Neurobiology, Care Sciences, and Society, Division of Curr Alzheimer Res. 2009 Sep 28.

View more research publications.

Press Releases on ACHE:

BioPortfolio Logo
National Transitions of Care Coalition Releases Health Care Tools in Spanish and French 5th October, 2009 National Transitions of Care Coalition

LITTLE ROCK, Ark., Oct. 5 /PRNewswire/ -- Today, the National Transitions of Care Coalition (NTOCC) released Spanish and French translations of patient/caregiver tools,

CMSA Announces Incoming President, Officers, and Directors 7th July, 2009 Case Management Society of America

Leaders Installed During CMSA's 19th Annual Conference & Expo

LITTLE ROCK, Ark., July 7 /PRNewswire-USNewswire/ -- The Case Management Society of America (CMSA)

Hahnemann COO Elected to the Pennsylvania Trauma System Foundation Board 7th April, 2009 Hahnemann University Hospital

PHILADELPHIA, April 7 /PRNewswire-USNewswire/ -- Hahnemann University Hospital is pleased to announce that its Chief Operating Officer, James B. Burke, FACHE, has been appointed to the

MicroMass Promotes Kim Levy To Senior Vice President 2nd April, 2009 MicroMass Communications, Inc.

CARY, N.C., April 2 /PRNewswire/ -- MicroMass Communications, Inc., a leader in behavioral science-based relationship marketing in the healthcare industry, has promoted Kim Levy to senior vice

New Focus Placed on Alternative Financing as Hospitals Seek Competitive Advantage During Challenging Economic Conditions 26th March, 2009 Elekta Inc.

Specialized Leases from Elekta Facilitate Sharing of Financial Risk and Return

ATLANTA, March 26 /PRNewswire/ -- Hospitals and health systems are facing a "perfect

BioNews Results for ACHE

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Advance for Nurses:  Nov 7 2009 3:11AM Matching: ache
Architecture and distribution of human corneal nerves.
British Journal of Ophthalmology:  Nov 5 2009 4:03AM Matching: ache
Canadian researchers and industrial partner print biosensors on paper to rapidly detect toxins
Bioscience World/Biotechnology Focus:  Oct 25 2009 8:36PM Matching: ache
Endo Pharma upgraded before FDA ruling on Fortesta; analyst says profits will top views
Cafepharma:  Oct 7 2009 9:58PM Matching: ache

Clinical Trials:

Clinical Trials Logo
Evaluation of Stepped Care for Chronic Pain in Iraq/Afghanistan Veterans (ESCAPE)

Patents:

Patents logo
US Patent No.Title
7524494 Degradation of hydrophobic ester pesticides and toxins
7553932 Methods of treating viral infection with IL-10 receptor antagonists
7555345 Implantable neurostimulator device
7557089 Use of derivatives of succinate esters for the treatment of dementia
7557092 Purinergic modulation of smell

View more patents.

ACHE results (if any) from reagent suppliers

Google CSE Logo
AChE Antibody / AChE Antibodies
AChE Antibody / AChE Antibodies. ... AChE specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-ache.html...

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ACHE Antibody (C-term)
Western blot analysis of anti-ACHE Antibody (N-term) (Cat. ... Formalin-fixed and paraffin-embedded human brain tissue reacted with ACHE antibody (C-term) ...
http://www.abgent.com/products/catalog_no/AP7853b_ACHE_Antib...

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AChE (4E11) Antibody sc-80614
AChE shRNA (h) Lentiviral Particles, sc-29628-V, 200 µl ... AChE (4E11): sc- 80614. Western blot analysis of AChE expression in 293T (A) and SW-13 (B) whole
...
http://www.scbt.com/datasheet-80614-ache-4e11-antibody.html...

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GeneTex Inc. - Your source for monoclonal, polyclonal, primary ...
It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational ...
http://www.genetex.com/WebPage/Product/ProductDetail.aspx?Ca...

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AChE (H-134) Antibody sc-11409
See how others have used AChE (H-134): sc-11409 antibody and or AChE (H-134) ... AChE siRNA (h): sc-29628. Western blot analysis of AChE expression in ...
http://www.scbt.com/datasheet-11409-ache-h-134-antibody.html...

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Anti-Acetylcholinesterase Monoclonal Antibody
HYB 190-01-02 is specific for brain AChE and does not recognize AChE from erythrocytes. The antibody can thus distinguish between mammalian brain AChE and
...
http://www.bioreagents.com/products/productDetails/productDe...

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AChE (E-19) Antibody sc-6432
See how others have used AChE (E-19): sc-6432 antibody and or AChE (E-19) ... Western blot analysis of AChE expression in untreated (A) and NGF-treated ...
http://www.scbt.com/datasheet-6432-ache-e-19-antibody.html...

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