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MMP1


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Symbol:MMP1
Name(s):matrix metallopeptidase 1 (interstitial collagenase)
Type:protein-coding
Organism:Homo sapiens
Synonyms:CLG, CLGN
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17697361 TauCl differentially inhibits the expression of MMP-1 and MMP-13in human synoviocytes.
18259971 Alveolar macrophage matrix metalloproteinase 1 and 12 may have a role in the lung structural changes leading to the development of emphysema.
18027871 upregulation of MT1-MMP by GM-CSF must only occur in cells directly involved in tubule formation
18097620 Observational study of gene-disease association. (HuGE Navigator)
18276095 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18164995 Investigation of cellular responses to experimental phonation may provide insight into how matrix metalloproteinases and other extracellular matrices contribute to maintenance of the vocal fold and development of pathology.
18060744 IL-1beta and MIF cytokine network induce MMP-1 and contribute to the loss of interstitial collagen in skin photoaging
15718477 Observational study of gene-disease association. (HuGE Navigator)
15767330 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15832405 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDbasiginmatrix metalloproteinase 1 preproprotein--Pubmed
HPRDbasiginmatrix metalloproteinase 1 preproprotein--Pubmed
HPRDbasigin isoform 1 precursormatrix metalloproteinase 1 preproprotein--Pubmed
BINDcoagulation factor II receptor precursormatrix metalloproteinase 1 preproproteinMMP-1 interacts with PAR1.-Pubmed
HPRDintegrin alpha 2 precursormatrix metalloproteinase 1 preproprotein--Pubmed
HPRDintegrin alpha 2 precursormatrix metalloproteinase 1 preproprotein--Pubmed
HPRDMatrix metalloproteinase 1matrix metalloproteinase 7 preproprotein--Pubmed
HPRDMatrix metalloproteinase 1chondroitin sulfate proteoglycan BEHAB/brevican--Pubmed
HPRDMatrix metalloproteinase 1brevican isoform 1--Pubmed
HPRDmatrix metalloproteinase 1 preproproteinMatrix metalloproteinase 7--Pubmed

Recent Publications on MMP1:

Pubmed Logo
Polymorphisms in the promoter regions of matrix metalloproteinases 1 and 3 and cancer risk: a meta-analysis of 50 case-control studies.
Matrix metalloproteinase (MMP) 1 and MMP3 are enzymes that degrade the...
22nd October, 2009
State Key Laboratory of Genetic Engineering, Institute of Genetics, School Mutagenesis. 2009 Oct 20.
DOI Direct Link
Matrilin-3 activates the expression of osteoarthritis-associated genes in primary human chondrocytes.
Here, we tested the matrilin-3-dependent induction of...
21st October, 2009
Institute for Clinical Chemistry, University of Cologne, Germany. FEBS Lett. 2009 Oct 17.
DOI Direct Link
Clinical relevance of nine transcriptional molecular markers for the diagnosis of head and neck squamous cell carcinoma in tissue and saliva rinse.
BACKGROUND: Analysis of 23 published transcriptome studies allowed us to...
20th October, 2009
Service d'ORL et Chirurgie Maxillo-faciale, Centre Hospitalier BMC Cancer. 2009 Oct 18;9:370.
DOI Direct Link
A Functional Polymorphism in MMP1 Could Influence Osteomyelitis Development.
Abstract Osteomyelitis (OM) is a bone infection characterised by necrosis...
14th October, 2009
J Bone Miner Res. 2009 Oct 12.
DOI Direct Link
Novel strategy to identify genetic risk factors for COPD severity: a genetic isolate.
Studies using genetic isolates with limited genetic variation may be...
3rd October, 2009
University Medical Center Groningen, University of Groningen, Groningen, Eur Respir J. 2009 Sep 24.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Matrix Metalloproteinase-1/Tissue Inhibitor of Metalloproteinase-1 (MMP-1/TIMP-1) Ratio and Diabetic Foot Ulcers

Patents:

Patents logo
US Patent No.Title
7312229 21-Heterocyclic-4-azasteroid derivatives as androgen receptor modulators
7402669 Method for preparing a Centella asiatica extract rich in madecassoside and in terminoloside
7405225 Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
7410770 Method for monitoring collagen type II degradation in cartilage
7413903 Methods of regulating differentiation in stem cells

View more patents.

MMP1 results (if any) from reagent suppliers

Google CSE Logo
MMP1 antibody (ab14058) | Abcam
Chicken polyclonal to MMP1. The matrix metalloproteinases (MMPs) are a family of at least eighteen secreted and membrane bound zincendopeptidases.
http://www.abcam.com/MMP1-antibody-ab14058.html...

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Monoclonal Anti-human Pro MMP-1 Antibody
This antibody has been selected for its ability to bind human Pro MMP-1. ... human Pro MMP-1 is approximately 100 ng/lane under reducing conditions. ...
http://www.rndsystems.com/pdf/mab900.pdf...

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MT-MMP-1 (V-16) Antibody sc-12366
See how others have used MT-MMP-1 (V-16): sc-12366 antibody and or MT-MMP-1 ... Western blot analysis of MT-MMP-1 expression in MIA PaCa-2 (A) and MCF7 (B) ...
http://www.scbt.com/datasheet-12366-mt-mmp-1-v-16-antibody.h...

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Purified Anti-MMP1 Antibody - BioLegend
Purified Anti-MMP1 Antibody - Matrix metalloproteinases (MMPs) are zinc- dependent endopeptidases that degrade substances within the extracellular matrix
.
http://www.biolegend.com/purified-anti-mmp1-antibody-4471.ht...

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Anti-MMP1 Monoclonal Antibody
Monoclonal Antibody against MMP1 for use in Immunohistochemistry, Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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MMP-1 (3B6) Antibody sc-21731
See how others have used MMP-1 (3B6): sc-21731 antibody and or MMP-1 (3B6) ... Elevated gene expression of MMP-1, MMP-10, and TIMP-1 reveal changes of ...
http://www.scbt.com/datasheet-21731-mmp-1-3b6-antibody.html...

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Anti-MMP1 Polyclonal Antibody
Polyclonal Antibody against MMP1 for use in Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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