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«MTHFR

Below is an extended MTHFR publications listing. Click here to return to the gene page.

Gene Information from Publications

Publication Link Summary of findings
17976958 T allele subjects, the risk was almost four times greater, despite similar antipsychotic exposure. Both waist circumference and MTHFR genotype significantly predicted insulin resistance
18257130 MTHFR and MTRR gene mutation alleles are related to Down syndrome, and CT, TT and GG gene mutation types increase the risk of Down syndrome
17900242 The MTHFR C677T polymorphism may play a role in influencing liver fibrosis progression in patients with recurrent hepatitis C, in conjunction with donor age, but not via steatosis promotion.
18065414 ER stress increases MTHFR expression and IRE1 and c-Jun mediate this activation
18199718 A significant association was found between MTHFR C677T genetic polymorphism and CpG island methylation status of MGMT gene
18333414 Mutation of MTHFR C677T is associated with fetal loss in first trimester.
18199722 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18200034 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18203168 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18204887 Observational study of gene-disease association. (HuGE Navigator)
18204969 Observational study of gene-disease association. (HuGE Navigator)
18205772 Observational study of gene-disease association. (HuGE Navigator)
18214047 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18220034 Observational study of gene-disease association. (HuGE Navigator)
18221821 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18222012 Observational study of gene-disease association. (HuGE Navigator)
18223316 Observational study of gene-disease association. (HuGE Navigator)
18225686 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18234410 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18235909 Observational study of gene-disease association. (HuGE Navigator)
18245544 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18249021 Observational study of gene-disease association. (HuGE Navigator)
18249399 Observational study of gene-disease association. (HuGE Navigator)
18255072 Observational study of gene-disease association. (HuGE Navigator)
18257130 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18258338 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18266839 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18267032 Observational study of gene-disease association. (HuGE Navigator)
18273817 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18274813 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18275512 Observational study of gene-disease association. (HuGE Navigator)
18277167 Meta-analysis and HuGE review of gene-disease association. (HuGE Navigator)
18280442 Observational study of gene-disease association. (HuGE Navigator)
18285546 Observational study of gene-disease association. (HuGE Navigator)
18293456 Observational study of gene-disease association. (HuGE Navigator)
18297176 Observational study of genotype prevalence. (HuGE Navigator)
18299612 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18317335 Observational study of gene-disease association. (HuGE Navigator)
18318759 Observational study of gene-disease association. (HuGE Navigator)
18322814 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18328637 Observational study of gene-disease association. (HuGE Navigator)
18333414 Observational study of gene-disease association. (HuGE Navigator)
18339682 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18340404 Meta-analysis of gene-disease association. (HuGE Navigator)
18350248 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
18350352 Observational study of gene-disease association. (HuGE Navigator)
18351371 Observational study of gene-disease association. (HuGE Navigator)
18352978 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18355300 Observational study of gene-disease association. (HuGE Navigator)
18070159 No evidence of associations between the MTHFR C677T variant allele and atopy, allergy or asthma in mothers or children was found.
18174236 the MTHFR and MTRR polymorphisms are associated with individual susceptibility to breast cancer among postmenopausal women
18162478 Finds association between an increased risk of gastric cancer and low folate levels in C677T polymorphism, but no such association in A1298C polymorphism.
17589670 the homozygous 5,10-methylenetetrahydrofolate reductase C677T genotype was not a risk factor for ischemic stroke
18068006 677 C/T MTHFR polymorphism is an independent risk factor for essential hypertension but not for coronary artery disease.
18202788 MTHFR-A1298C homozygous CC might direct the methylation rather than the synthesis of DNA, and result in the methylation of several tumor suppressor genes such as TIMP3.
18293456 The researchers found no association between MTHFR-677 and MTHFR-1298 polymorphisms with occlusive artery disease or deep venous thrombosis.
17712558 Saudi individuals carrying MTHFR genotype 1298CC & the 1298C allele had 4.23 and 1.73-fold higher risk of developing diffuse large B-cell lymphoma, respectively.
18273817 The presence of the genetic polymorphism of MTHFR is a maternal risk factor for Down syndrome in Brazil.
17951123 This study indicates that although the maternal MTHFR genotype may confer susceptibility to the teratogenic effect of AEDs, particularly VPA, it is likely that the main teratogenic effects are mediated through other mechanisms.
17965025 Fetal viability is directly related to the CC genotype as a protector while the three and four mutation MTHFR genotypes appear to be a determinant on fetal non-viability and spontaneous abortion
18192106 factor V Leiden, the G20210A prothrombin gene mutation, and the C677T MTHFR gene mutation are not genetic risk factors among Thai patients with VTE.
18053312 results suggest that the role of folate metabolism in colorectal cancer aetiology may be very complex. Investigation of particular folate vitamers (for example, tetrahydrofolate, 5,10-methylenetetrahydrofolate) may help clarify carcinogenesis pathways.
15979034 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15830056 Observational study of gene-disease association. (HuGE Navigator)
15831156 Observational study of gene-disease association. (HuGE Navigator)
15834031 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15834246 Observational study of genotype prevalence. (HuGE Navigator)
15834927 Observational study of gene-disease association. (HuGE Navigator)
15836661 Observational study of gene-disease association. (HuGE Navigator)
15837084 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
15837541 Observational study of gene-disease association. (HuGE Navigator)
15840047 Observational study of gene-disease association. (HuGE Navigator)
15842353 Observational study of gene-disease association. (HuGE Navigator)
15843209 Observational study of genetic testing. (HuGE Navigator)
15847749 Observational study of gene-disease association. (HuGE Navigator)
15866085 Observational study of gene-disease association. (HuGE Navigator)
15867278 Observational study of gene-disease association. (HuGE Navigator)
15868433 Observational study of gene-disease association. (HuGE Navigator)
15886665 Observational study of gene-disease association. (HuGE Navigator)
15886801 Observational study of gene-disease association. (HuGE Navigator)
15889417 Observational study of gene-disease association. (HuGE Navigator)
15889539 Observational study of gene-disease association. (HuGE Navigator)
15893594 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15894672 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15895286 Clinical trial of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15902512 Meta-analysis of gene-disease association. (HuGE Navigator)
15905108 Observational study of gene-disease association. (HuGE Navigator)
15912197 Observational study of gene-disease association. (HuGE Navigator)
15914210 Observational study of gene-disease association. (HuGE Navigator)
15916056 Observational study of gene-disease association. (HuGE Navigator)
15921520 Observational study of gene-disease association. (HuGE Navigator)
15922487 Observational study of gene-disease association. (HuGE Navigator)
15929053 Observational study of gene-disease association. (HuGE Navigator)
15934123 Observational study of gene-disease association. (HuGE Navigator)
15935452 Observational study of gene-environment interaction. (HuGE Navigator)
15937947 Observational study of gene-disease association. (HuGE Navigator)
15941899 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15941958 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15941959 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15941973 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15947278 Meta-analysis of gene-disease association. (HuGE Navigator)
15947552 Observational study of gene-disease association. (HuGE Navigator)
15949101 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15950563 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15952099 Observational study of gene-disease association. (HuGE Navigator)
15952129 Observational study of gene-disease association. (HuGE Navigator)
15952646 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15953655 Observational study of gene-disease association. (HuGE Navigator)
15968383 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
15969978 Observational study of gene-environment interaction. (HuGE Navigator)
15970629 Observational study of gene-disease association. (HuGE Navigator)
15973722 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
12871600 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
12875914 Observational study of gene-disease association. (HuGE Navigator)
12877902 Observational study of gene-disease association. (HuGE Navigator)
12879654 Observational study of gene-disease association. (HuGE Navigator)
12883704 Observational study of gene-disease association. (HuGE Navigator)
12883749 Observational study of gene-disease association. (HuGE Navigator)
12889841 Observational study of gene-disease association. (HuGE Navigator)
12897091 Observational study of gene-disease association. (HuGE Navigator)
12899665 Observational study of gene-disease association. (HuGE Navigator)
12901511 Observational study of gene-disease association. (HuGE Navigator)
12901638 Observational study of gene-disease association. (HuGE Navigator)
12907815 Observational study of gene-disease association. (HuGE Navigator)
12911562 Observational study of gene-disease association. (HuGE Navigator)
12914571 Observational study of gene-disease association. (HuGE Navigator)
12915598 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
12923155 Observational study of gene-disease association. (HuGE Navigator)
12927690 Observational study of gene-disease association. (HuGE Navigator)
12928053 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12928694 Observational study of gene-disease association. (HuGE Navigator)
12939653 Observational study of gene-disease association. (HuGE Navigator)
12951177 Observational study of gene-disease association. (HuGE Navigator)
12956845 Observational study of gene-disease association. (HuGE Navigator)
12958073 Observational study of gene-disease association. (HuGE Navigator)
12964809 Observational study of genotype prevalence. (HuGE Navigator)
12975018 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
14499487 Observational study of gene-disease association. (HuGE Navigator)
14504916 Observational study of gene-disease association. (HuGE Navigator)
14508198 Observational study of gene-disease association. (HuGE Navigator)
14521457 Observational study of gene-disease association. (HuGE Navigator)
14535593 Observational study of gene-disease association. (HuGE Navigator)
14556201 Observational study of genetic testing. (HuGE Navigator)
14560345 Observational study of gene-disease association. (HuGE Navigator)
14569745 Observational study of gene-disease association. (HuGE Navigator)
14572159 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
14578131 Observational study of gene-disease association. (HuGE Navigator)
14580166 Observational study of gene-disease association. (HuGE Navigator)
14580229 Observational study of genetic testing. (HuGE Navigator)
14581802 Observational study of gene-disease association. (HuGE Navigator)
14585765 Observational study of gene-disease association. (HuGE Navigator)
14586640 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
14594111 Observational study of gene-disease association. (HuGE Navigator)
14597244 Observational study of gene-disease association. (HuGE Navigator)
14603192 Observational study of gene-disease association. (HuGE Navigator)
14604831 Observational study of gene-disease association. (HuGE Navigator)
14607573 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
14608052 Observational study of gene-disease association. (HuGE Navigator)
14613740 Observational study of gene-disease association. (HuGE Navigator)
14614398 Observational study of genotype prevalence. (HuGE Navigator)
14616766 Observational study of gene-disease association. (HuGE Navigator)
17855693 Observational study of gene-disease association. (HuGE Navigator)
17891500 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
17891601 Observational study of gene-disease association. (HuGE Navigator)
17899317 Observational study of gene-disease association. (HuGE Navigator)
17900242 Observational study of gene-disease association. (HuGE Navigator)
17904003 Observational study of gene-disease association. (HuGE Navigator)
17904392 Observational study of gene-disease association. (HuGE Navigator)
17904970 Observational study of gene-disease association. (HuGE Navigator)
17911197 Observational study of gene-disease association. (HuGE Navigator)
17914182 Observational study of gene-disease association. (HuGE Navigator)
17917766 Observational study of gene-disease association. (HuGE Navigator)
17918782 Observational study of genotype prevalence. (HuGE Navigator)
17920311 Meta-analysis of gene-disease association. (HuGE Navigator)
17922421 Observational study of gene-disease association. (HuGE Navigator)
17925002 Observational study of gene-disease association. (HuGE Navigator)
17932993 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17934692 Meta-analysis of gene-disease association and gene-gene interaction. (HuGE Navigator)
17934972 Observational study of gene-disease association. (HuGE Navigator)
17951123 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17957761 Observational study of genotype prevalence. (HuGE Navigator)
17962595 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17963764 Observational study of gene-disease association. (HuGE Navigator)
17965025 Observational study of gene-disease association. (HuGE Navigator)
17965089 Meta-analysis of gene-disease association. (HuGE Navigator)
17965559 Observational study of gene-disease association. (HuGE Navigator)
17966140 Observational study of gene-disease association. (HuGE Navigator)
17966954 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17967524 Observational study of gene-disease association. (HuGE Navigator)
17970089 Observational study of gene-disease association. (HuGE Navigator)
17971770 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17972183 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17974190 Observational study of gene-disease association. (HuGE Navigator)
17976958 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17979520 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17982733 Observational study of gene-disease association. (HuGE Navigator)
17993766 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17999084 Observational study of gene-disease association. (HuGE Navigator)
18004208 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18019157 Observational study of gene-disease association. (HuGE Navigator)
18022874 Observational study of gene-disease association. (HuGE Navigator)
18023275 Observational study of gene-disease association. (HuGE Navigator)
18034620 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18034637 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18040753 Observational study of gene-disease association. (HuGE Navigator)
18053312 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18053808 Observational study of gene-disease association. (HuGE Navigator)
18057532 Observational study of gene-disease association. (HuGE Navigator)
12042673 Observational study of gene-disease association. (HuGE Navigator)
12045051 Observational study of gene-disease association. (HuGE Navigator)
12049191 Observational study of gene-disease association. (HuGE Navigator)
12049616 Observational study of gene-disease association. (HuGE Navigator)
12052604 Observational study of gene-disease association. (HuGE Navigator)
12060127 Observational study of gene-disease association. (HuGE Navigator)
12080391 Observational study of gene-disease association. (HuGE Navigator)
12081832 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
12082592 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
12087901 Observational study of gene-disease association. (HuGE Navigator)
12095808 Observational study of gene-disease association. (HuGE Navigator)
12097536 Observational study of gene-disease association. (HuGE Navigator)
12097662 Observational study of gene-disease association. (HuGE Navigator)
12111380 Observational study of gene-disease association. (HuGE Navigator)
12115343 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12122980 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12123235 Observational study of gene-disease association. (HuGE Navigator)
12123675 Observational study of gene-disease association and genetic testing. (HuGE Navigator)
12133463 Observational study of gene-disease association. (HuGE Navigator)
12138370 Observational study of gene-disease association. (HuGE Navigator)
12143122 Observational study of gene-disease association. (HuGE Navigator)
12146133 Observational study of genotype prevalence. (HuGE Navigator)
12154064 Observational study of gene-disease association. (HuGE Navigator)
12164325 Observational study of genotype prevalence. (HuGE Navigator)
12165282 Observational study of gene-disease association. (HuGE Navigator)
12170465 Observational study of gene-disease association. (HuGE Navigator)
12180000 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12180146 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12186157 Observational study of gene-disease association. (HuGE Navigator)
12187094 Observational study of gene-disease association. (HuGE Navigator)
12194796 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12196500 Observational study of gene-disease association. (HuGE Navigator)
12196644 Meta-analysis of gene-disease association. (HuGE Navigator)
12204804 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12214149 Meta-analysis of gene-disease association. (HuGE Navigator)
12215845 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12218328 Observational study of gene-disease association. (HuGE Navigator)
12221667 Observational study of gene-disease association. (HuGE Navigator)
12232679 Observational study of gene-disease association. (HuGE Navigator)
12237638 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12356186 Observational study of gene-disease association. (HuGE Navigator)
12356947 Observational study of gene-disease association. (HuGE Navigator)
12364720 Observational study of gene-disease association. (HuGE Navigator)
12380673 Observational study of gene-disease association. (HuGE Navigator)
12382154 Observational study of gene-disease association. (HuGE Navigator)
12384649 Observational study of gene-disease association. (HuGE Navigator)
12387655 Meta-analysis of gene-disease association and gene-environment interaction. (HuGE Navigator)
12411076 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17228344 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17243563 Observational study of gene-disease association. (HuGE Navigator)
17259654 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17260091 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
17264399 Observational study of gene-disease association. (HuGE Navigator)
17274465 Observational study of gene-disease association. (HuGE Navigator)
17275478 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17277043 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17278618 Observational study of genotype prevalence. (HuGE Navigator)
17284634 Observational study of gene-disease association. (HuGE Navigator)
17287626 Observational study of gene-disease association. (HuGE Navigator)
17290027 Observational study of gene-disease association. (HuGE Navigator)
17298693 Observational study of gene-disease association. (HuGE Navigator)
17300365 Observational study of gene-disease association. (HuGE Navigator)
17301261 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17303386 Observational study of gene-disease association. (HuGE Navigator)
17306151 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
17311050 Observational study of gene-disease association. (HuGE Navigator)
17311259 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17311260 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
17317888 Observational study of gene-disease association. (HuGE Navigator)
17323057 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17323822 Observational study of gene-disease association. (HuGE Navigator)
17332146 Observational study of gene-disease association. (HuGE Navigator)
17333388 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17334320 Observational study of gene-disease association. (HuGE Navigator)
17334642 Observational study of gene-disease association. (HuGE Navigator)
17339646 Observational study of gene-disease association. (HuGE Navigator)
17344026 Observational study of gene-disease association. (HuGE Navigator)
17350979 Observational study of gene-disease association. (HuGE Navigator)
17353498 Observational study of gene-disease association. (HuGE Navigator)
17354258 Observational study of gene-disease association. (HuGE Navigator)
17356914 Observational study of gene-disease association. (HuGE Navigator)
17365577 Observational study of gene-disease association. (HuGE Navigator)
17367411 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17372271 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17384833 Observational study of gene-disease association. (HuGE Navigator)
17389614 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17395259 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
17401546 Observational study of gene-disease association. (HuGE Navigator)
17407503 Observational study of gene-disease association. (HuGE Navigator)
17408107 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17412321 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17412799 Observational study of gene-disease association. (HuGE Navigator)
17418558 Observational study of gene-disease association. (HuGE Navigator)
17431894 Meta-analysis of gene-disease association. (HuGE Navigator)
17436239 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16936070 Observational study of gene-disease association. (HuGE Navigator)
16936384 Observational study of gene-disease association. (HuGE Navigator)
16938111 Observational study of gene-disease association. (HuGE Navigator)
16941173 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16944145 Observational study of gene-disease association. (HuGE Navigator)
16950800 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16956909 Observational study of gene-disease association. (HuGE Navigator)
16958597 Observational study of gene-disease association. (HuGE Navigator)
16963292 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16969279 Observational study of gene-disease association. (HuGE Navigator)
16985020 Clinical trial of gene-disease association. (HuGE Navigator)
16986504 Observational study of gene-disease association. (HuGE Navigator)
16987799 Observational study of gene-disease association. (HuGE Navigator)
16997330 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16999862 Observational study of gene-disease association. (HuGE Navigator)
17000243 Observational study of gene-disease association. (HuGE Navigator)
17000685 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17000887 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17003923 Observational study of genotype prevalence. (HuGE Navigator)
17005242 Observational study of gene-disease association. (HuGE Navigator)
17005529 Observational study of gene-disease association. (HuGE Navigator)
17008978 Observational study of genotype prevalence. (HuGE Navigator)
17009149 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17009228 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17010581 Observational study of gene-disease association. (HuGE Navigator)
17016617 Observational study of gene-disease association. (HuGE Navigator)
17024475 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17024648 Observational study of gene-disease association. (HuGE Navigator)
17028897 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17030196 Meta-analysis of gene-disease association and gene-environment interaction. (HuGE Navigator)
17035141 Observational study of gene-disease association. (HuGE Navigator)
17035405 Meta-analysis of gene-disease association. (HuGE Navigator)
17036383 Observational study of gene-disease association. (HuGE Navigator)
17043779 Observational study of gene-disease association. (HuGE Navigator)
17047490 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17053001 Observational study of gene-disease association. (HuGE Navigator)
17063264 Observational study of gene-disease association. (HuGE Navigator)
17065574 Observational study of gene-disease association. (HuGE Navigator)
17065682 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17069650 Observational study of gene-disease association. (HuGE Navigator)
17071478 Observational study of gene-disease association. (HuGE Navigator)
17074326 Meta-analysis of gene-disease association. (HuGE Navigator)
17074544 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17074966 Meta-analysis and HuGE review of gene-disease association. (HuGE Navigator)
17085942 Observational study of gene-disease association. (HuGE Navigator)
17087956 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17089070 Meta-analysis of gene-disease association. (HuGE Navigator)
15559724 Observational study of genotype prevalence. (HuGE Navigator)
15561486 Observational study of gene-environment interaction. (HuGE Navigator)
15564899 Observational study of gene-disease association. (HuGE Navigator)
15569990 Observational study of gene-disease association. (HuGE Navigator)
15576297 Observational study of genetic testing. (HuGE Navigator)
15576298 Observational study of gene-disease association. (HuGE Navigator)
15581963 Observational study of gene-disease association. (HuGE Navigator)
15582752 Observational study of gene-disease association. (HuGE Navigator)
15582924 Observational study of gene-disease association. (HuGE Navigator)
15583437 Observational study of gene-disease association. (HuGE Navigator)
15585767 Observational study of gene-disease association. (HuGE Navigator)
15589218 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
15595935 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15598763 Observational study of gene-disease association. (HuGE Navigator)
15598777 Observational study of gene-disease association. (HuGE Navigator)
15598791 Observational study of gene-disease association. (HuGE Navigator)
15607533 Observational study of gene-disease association. (HuGE Navigator)
15608557 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15609280 Observational study of gene-disease association. (HuGE Navigator)
15612980 Observational study of gene-disease association. (HuGE Navigator)
15613145 Observational study of gene-disease association. (HuGE Navigator)
15617551 Observational study of gene-disease association. (HuGE Navigator)
15618240 Observational study of gene-disease association. (HuGE Navigator)
15621215 Observational study of gene-disease association. (HuGE Navigator)
15625161 Meta-analysis of gene-disease association. (HuGE Navigator)
15633187 Observational study of gene-disease association. (HuGE Navigator)
15635481 Observational study of gene-disease association. (HuGE Navigator)
15643524 Observational study of gene-disease association. (HuGE Navigator)
15648053 Observational study of gene-disease association. (HuGE Navigator)
15666596 Observational study of genotype prevalence. (HuGE Navigator)
15670035 Meta-analysis of gene-disease association. (HuGE Navigator)
15681105 Observational study of gene-disease association. (HuGE Navigator)
15682292 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15686674 Observational study of gene-disease association. (HuGE Navigator)
15688408 Observational study of gene-disease association. (HuGE Navigator)
15691154 Observational study of gene-disease association. (HuGE Navigator)
15692115 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15698398 Observational study of gene-disease association. (HuGE Navigator)
15716659 Observational study of gene-disease association. (HuGE Navigator)
15719048 Observational study of gene-disease association. (HuGE Navigator)
15729744 Meta-analysis of gene-disease association. (HuGE Navigator)
15735051 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15735067 Observational study of gene-disease association. (HuGE Navigator)
15735068 Observational study of gene-environment interaction. (HuGE Navigator)
15735113 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15736423 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15750260 Observational study of gene-disease association. (HuGE Navigator)
15755387 Observational study of gene-disease association. (HuGE Navigator)
15764293 Observational study of gene-disease association. (HuGE Navigator)
15765596 Observational study of gene-disease association. (HuGE Navigator)
15769328 Observational study of gene-disease association. (HuGE Navigator)
15769364 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15775757 Observational study of gene-disease association. (HuGE Navigator)
15777550 Observational study of gene-disease association. (HuGE Navigator)
15777680 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15781665 Observational study of gene-disease association. (HuGE Navigator)
15784506 Observational study of gene-disease association. (HuGE Navigator)
15785306 Observational study of gene-disease association. (HuGE Navigator)
15790048 Observational study of gene-disease association. (HuGE Navigator)
15790587 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15793792 Observational study of genotype prevalence. (HuGE Navigator)
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15806605 Observational study of gene-disease association. (HuGE Navigator)
15808177 Observational study of gene-disease association. (HuGE Navigator)
15811073 Observational study of gene-disease association. (HuGE Navigator)
15813553 Observational study of gene-disease association. (HuGE Navigator)
15820491 Observational study of gene-disease association. (HuGE Navigator)
15821810 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15824167 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
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15469701 Observational study of gene-disease association. (HuGE Navigator)
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15481892 Observational study of genotype prevalence. (HuGE Navigator)
15492840 Observational study of gene-disease association. (HuGE Navigator)
15494775 Observational study of gene-disease association. (HuGE Navigator)
15503105 Observational study of gene-disease association. (HuGE Navigator)
15510613 Observational study of gene-disease association. (HuGE Navigator)
15514263 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15514969 Observational study of gene-environment interaction. (HuGE Navigator)
15515881 Observational study of gene-disease association. (HuGE Navigator)
15520876 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15523694 Observational study of gene-disease association. (HuGE Navigator)
15525878 Observational study of gene-disease association. (HuGE Navigator)
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15528884 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15531855 Observational study of gene-disease association. (HuGE Navigator)
15533596 Observational study of gene-disease association. (HuGE Navigator)
15534175 Meta-analysis of gene-disease association. (HuGE Navigator)
15546509 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
15547928 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
15551285 Observational study of gene-disease association. (HuGE Navigator)
15554031 Observational study of gene-disease association. (HuGE Navigator)
15044114 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
15458711 Observational study of gene-disease association. (HuGE Navigator)
12419832 Observational study of gene-disease association. (HuGE Navigator)
12421498 Observational study of gene-disease association. (HuGE Navigator)
12428084 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12430180 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12431255 Observational study of gene-disease association. (HuGE Navigator)
12433726 Observational study of gene-disease association. (HuGE Navigator)
12439143 Observational study of gene-disease association. (HuGE Navigator)
12442281 Observational study of gene-disease association. (HuGE Navigator)
12446192 Observational study of gene-disease association. (HuGE Navigator)
12453860 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
12454577 Observational study of gene-disease association. (HuGE Navigator)
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12469051 Observational study of gene-disease association. (HuGE Navigator)
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12473175 Observational study of gene-disease association. (HuGE Navigator)
12480755 Observational study of gene-disease association. (HuGE Navigator)
12488908 Observational study of gene-disease association. (HuGE Navigator)
12496052 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12499324 Observational study of gene-disease association. (HuGE Navigator)
12514663 Observational study of gene-disease association. (HuGE Navigator)
12518110 Observational study of genotype prevalence. (HuGE Navigator)
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12534444 Observational study of gene-disease association. (HuGE Navigator)
12540022 Observational study of gene-disease association. (HuGE Navigator)
12547903 Observational study of gene-disease association. (HuGE Navigator)
12560354 Observational study of gene-environment interaction. (HuGE Navigator)
12560871 Observational study and meta-analysis of genotype prevalence. (HuGE Navigator)
12570104 Observational study of gene-disease association. (HuGE Navigator)
12574198 Observational study of gene-disease association. (HuGE Navigator)
12576444 Observational study of gene-disease association. (HuGE Navigator)
12589326 Observational study of gene-disease association. (HuGE Navigator)
12590185 Observational study of gene-disease association. (HuGE Navigator)
12590188 Observational study of gene-disease association. (HuGE Navigator)
12594357 Observational study of genotype prevalence. (HuGE Navigator)
12600862 Observational study of gene-disease association. (HuGE Navigator)
12602921 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12605391 Observational study of gene-disease association. (HuGE Navigator)
12612987 Observational study of gene-disease association. (HuGE Navigator)
12614926 Observational study of gene-disease association. (HuGE Navigator)
12615788 Observational study of gene-disease association. (HuGE Navigator)
12618331 Observational study of gene-disease association. (HuGE Navigator)
12618332 Observational study of gene-disease association. (HuGE Navigator)
12623486 Observational study of gene-disease association. (HuGE Navigator)
12642343 Observational study of gene-disease association. (HuGE Navigator)
12644913 Observational study of gene-disease association. (HuGE Navigator)
12648076 Observational study of gene-disease association. (HuGE Navigator)
12649066 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12649184 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
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16711541 Observational study of gene-disease association. (HuGE Navigator)
16712703 Observational study of gene-disease association. (HuGE Navigator)
16737574 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16753154 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16758123 Meta-analysis of gene-disease association. (HuGE Navigator)
16758511 Observational study of gene-disease association. (HuGE Navigator)
16761446 Observational study of gene-disease association. (HuGE Navigator)
16765424 Observational study of gene-disease association. (HuGE Navigator)
16774768 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16777985 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16778415 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16783607 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16785472 Observational study of gene-disease association. (HuGE Navigator)
16787708 Observational study of gene-disease association. (HuGE Navigator)
16791607 Observational study of gene-disease association. (HuGE Navigator)
16792904 Observational study of gene-disease association. (HuGE Navigator)
16796406 Observational study of gene-disease association. (HuGE Navigator)
16799656 Observational study of gene-disease association. (HuGE Navigator)
16808252 Observational study of gene-disease association. (HuGE Navigator)
16819711 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16820193 Observational study of gene-disease association. (HuGE Navigator)
16821630 Observational study of gene-disease association. (HuGE Navigator)
16828193 Observational study of gene-disease association. (HuGE Navigator)
16839569 Observational study of gene-disease association. (HuGE Navigator)
16844951 Observational study of gene-disease association. (HuGE Navigator)
16845248 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16845273 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16861746 Observational study of gene-disease association. (HuGE Navigator)
16862068 Observational study of gene-disease association. (HuGE Navigator)
16862278 Observational study of gene-disease association. (HuGE Navigator)
16865747 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16867914 Observational study of gene-disease association. (HuGE Navigator)
16870553 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16875718 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16877991 Observational study of gene-disease association. (HuGE Navigator)
16881367 Observational study of gene-disease association. (HuGE Navigator)
16886608 Observational study of gene-disease association. (HuGE Navigator)
16888682 Observational study of gene-disease association. (HuGE Navigator)
16894458 Observational study of gene-disease association. (HuGE Navigator)
16894468 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16897583 Meta-analysis of gene-disease association. (HuGE Navigator)
16906320 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
16906459 Observational study of gene-disease association. (HuGE Navigator)
16917939 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16920564 Observational study of gene-disease association. (HuGE Navigator)
16923565 Observational study of gene-disease association. (HuGE Navigator)
16927418 Observational study of gene-disease association. (HuGE Navigator)
11025596 Observational study of gene-disease association. (HuGE Navigator)
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11054348 Observational study of gene-disease association. (HuGE Navigator)
11056246 Observational study of gene-disease association. (HuGE Navigator)
11058711 Meta-analysis of gene-disease association. (HuGE Navigator)
11062308 Observational study of gene-disease association. (HuGE Navigator)
11073851 Observational study of gene-disease association. (HuGE Navigator)
11074490 Observational study of gene-disease association. (HuGE Navigator)
11074524 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
11084577 Observational study of gene-disease association. (HuGE Navigator)
11085290 Observational study of gene-disease association. (HuGE Navigator)
11092508 Observational study of gene-disease association. (HuGE Navigator)
11094304 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
11096266 Observational study of gene-disease association. (HuGE Navigator)
11096270 Observational study of gene-disease association. (HuGE Navigator)
11098041 Observational study of gene-disease association. (HuGE Navigator)
11101473 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11108898 Observational study of genotype prevalence. (HuGE Navigator)
11118403 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
11121176 Observational study of gene-disease association. (HuGE Navigator)
11122096 Observational study of gene-disease association. (HuGE Navigator)
11124649 Observational study of gene-disease association. (HuGE Navigator)
11128675 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
11133719 Observational study of gene-disease association. (HuGE Navigator)
11142765 Observational study of genotype prevalence. (HuGE Navigator)
11146461 Observational study of gene-disease association. (HuGE Navigator)
11150582 Observational study of gene-disease association. (HuGE Navigator)
11155296 Observational study of gene-disease association. (HuGE Navigator)
11157318 Observational study of gene-disease association. (HuGE Navigator)
11161947 Meta-analysis of gene-disease association. (HuGE Navigator)
11168435 Observational study of gene-disease association. (HuGE Navigator)
11169021 Observational study of gene-disease association. (HuGE Navigator)
11170082 Observational study of gene-disease association. (HuGE Navigator)
11170083 Observational study of gene-disease association. (HuGE Navigator)
11177206 Observational study of gene-disease association. (HuGE Navigator)
11186937 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
11197244 Observational study of gene-disease association. (HuGE Navigator)
11204578 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11204591 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
11228493 Observational study of gene-disease association. (HuGE Navigator)
11252530 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11257266 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
11257267 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11259808 Observational study of gene-disease association. (HuGE Navigator)
11268732 Observational study of gene-disease association. (HuGE Navigator)
11274015 Observational study of gene-disease association. (HuGE Navigator)
11274424 Observational study of gene-disease association. (HuGE Navigator)
11281306 Observational study of gene-disease association. (HuGE Navigator)
16524890 Observational study of gene-disease association. (HuGE Navigator)
16533336 Observational study of gene-disease association. (HuGE Navigator)
16536307 Observational study of gene-disease association. (HuGE Navigator)
16538645 Observational study of gene-disease association. (HuGE Navigator)
16541270 Observational study of gene-disease association. (HuGE Navigator)
16545905 Observational study of gene-disease association. (HuGE Navigator)
16549163 Observational study of gene-disease association. (HuGE Navigator)
16556414 Observational study of gene-disease association. (HuGE Navigator)
16557227 Observational study of gene-disease association. (HuGE Navigator)
16564429 Observational study of gene-disease association. (HuGE Navigator)
16567932 Observational study of gene-disease association. (HuGE Navigator)
16572443 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16572609 Observational study of gene-disease association. (HuGE Navigator)
16573155 Observational study of gene-disease association. (HuGE Navigator)
16574759 Observational study of gene-disease association. (HuGE Navigator)
16575899 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16580699 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16595080 Meta-analysis of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16596679 Observational study of gene-disease association. (HuGE Navigator)
16599836 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16601831 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
16602021 Observational study of gene-disease association. (HuGE Navigator)
16604492 Observational study of genetic testing. (HuGE Navigator)
16607075 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16613994 Observational study of gene-disease association. (HuGE Navigator)
16614466 Observational study of gene-disease association. (HuGE Navigator)
16614955 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16621645 Observational study of gene-disease association. (HuGE Navigator)
16622263 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16624841 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16627623 Observational study of gene-disease association. (HuGE Navigator)
16629766 Observational study of gene-disease association. (HuGE Navigator)
16630166 Meta-analysis of gene-disease association. (HuGE Navigator)
16634455 Observational study of gene-disease association. (HuGE Navigator)
16635210 Observational study of gene-disease association. (HuGE Navigator)
16636653 Observational study of gene-disease association. (HuGE Navigator)
16641680 Observational study of gene-disease association. (HuGE Navigator)
16651869 Observational study of gene-disease association. (HuGE Navigator)
16679164 Observational study of gene-disease association. (HuGE Navigator)
16679643 Observational study of gene-disease association. (HuGE Navigator)
16681562 Observational study of gene-disease association. (HuGE Navigator)
16682831 Observational study of gene-disease association. (HuGE Navigator)
16686913 Observational study of gene-disease association. (HuGE Navigator)
16691128 Meta-analysis of gene-disease association. (HuGE Navigator)
16700986 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16704755 Observational study of gene-disease association. (HuGE Navigator)
16706930 Observational study of gene-disease association. (HuGE Navigator)
15985285 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15996400 Observational study of gene-disease association. (HuGE Navigator)
15996600 Observational study of gene-disease association. (HuGE Navigator)
16002796 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
16002814 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16006997 Observational study of gene-disease association. (HuGE Navigator)
16011963 Observational study of gene-disease association. (HuGE Navigator)
16013960 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16015422 Observational study of gene-disease association. (HuGE Navigator)
16019535 Observational study of gene-disease association. (HuGE Navigator)
16030402 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16045580 Observational study of gene-disease association. (HuGE Navigator)
16046727 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16051637 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16052395 Observational study of gene-disease association. (HuGE Navigator)
16053469 Observational study of gene-disease association. (HuGE Navigator)
16055253 Observational study of gene-disease association. (HuGE Navigator)
16055944 Observational study of gene-disease association. (HuGE Navigator)
16061406 Observational study of gene-disease association. (HuGE Navigator)
16076517 Observational study of gene-disease association. (HuGE Navigator)
16077191 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16081343 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16082606 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16084002 Observational study of gene-disease association. (HuGE Navigator)
16091654 Observational study of gene-disease association. (HuGE Navigator)
16093732 Observational study of genotype prevalence. (HuGE Navigator)
16094648 Observational study of gene-disease association. (HuGE Navigator)
16096524 Observational study of gene-disease association. (HuGE Navigator)
16097444 Observational study of gene-disease association. (HuGE Navigator)
16098865 Observational study of gene-disease association. (HuGE Navigator)
16100725 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16103455 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16108833 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16115349 Observational study of gene-disease association. (HuGE Navigator)
16123993 Observational study of gene-disease association. (HuGE Navigator)
16134079 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16135581 Observational study of gene-disease association. (HuGE Navigator)
16135938 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16141796 Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16142884 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16144556 Observational study of gene-disease association. (HuGE Navigator)
16145688 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
16152599 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16154434 Observational study of gene-disease association. (HuGE Navigator)
16158041 Observational study of gene-disease association. (HuGE Navigator)
14634838 Observational study of genotype prevalence. (HuGE Navigator)
14638877 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
14642003 Observational study of genotype prevalence. (HuGE Navigator)
14644077 Observational study of gene-disease association. (HuGE Navigator)
14644226 Meta-analysis of gene-disease association. (HuGE Navigator)
14647408 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
14650352 Observational study of gene-environment interaction. (HuGE Navigator)
14652285 Observational study of gene-disease association. (HuGE Navigator)
14652356 Observational study of gene-environment interaction. (HuGE Navigator)
14656021 Observational study of gene-disease association. (HuGE Navigator)
14656945 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
14660985 Meta-analysis of gene-disease association. (HuGE Navigator)
14669168 Observational study of gene-disease association. (HuGE Navigator)
14669613 Observational study of gene-disease association. (HuGE Navigator)
14677097 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
14677182 Observational study of gene-disease association. (HuGE Navigator)
14679361 Observational study of gene-disease association. (HuGE Navigator)
14688016 Observational study of gene-disease association. (HuGE Navigator)
14693836 Observational study of gene-disease association. (HuGE Navigator)
14698652 Observational study of gene-disease association. (HuGE Navigator)
14706682 Observational study of gene-disease association. (HuGE Navigator)
14716779 Observational study of genotype prevalence. (HuGE Navigator)
14717963 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
14727014 Observational study of gene-disease association. (HuGE Navigator)
14728017 Observational study of gene-disease association. (HuGE Navigator)
14734201 Observational study of gene-disease association. (HuGE Navigator)
14735580 Observational study of gene-disease association. (HuGE Navigator)
14737040 Observational study of gene-disease association. (HuGE Navigator)
14739536 Observational study of gene-disease association. (HuGE Navigator)
14742985 Observational study of gene-disease association. (HuGE Navigator)
14746952 Observational study of gene-disease association. (HuGE Navigator)
14763962 Observational study of gene-disease association. (HuGE Navigator)
14767907 Observational study of gene-disease association. (HuGE Navigator)
14973091 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
14973104 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
14977639 Meta-analysis and HuGE review of genotype prevalence, gene-disease association, and gene-environment interaction. (HuGE Navigator)
14981981 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
14994919 Observational study of gene-disease association. (HuGE Navigator)
15002923 Observational study of gene-disease association. (HuGE Navigator)
15003888 Observational study of gene-disease association. (HuGE Navigator)
15004488 Observational study of gene-disease association. (HuGE Navigator)
15007309 Observational study of gene-disease association. (HuGE Navigator)
15010895 Observational study of gene-disease association. (HuGE Navigator)
15022402 Observational study of gene-disease association. (HuGE Navigator)
15033038 Observational study of genotype prevalence. (HuGE Navigator)
15033905 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15040829 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18061941 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18062861 Meta-analysis of gene-disease association. (HuGE Navigator)
18068006 Observational study of gene-disease association. (HuGE Navigator)
18070159 Observational study of gene-disease association. (HuGE Navigator)
18070829 Observational study of gene-disease association. (HuGE Navigator)
18074111 Observational study of gene-disease association. (HuGE Navigator)
18074687 Observational study of gene-disease association. (HuGE Navigator)
18075008 Observational study of gene-disease association. (HuGE Navigator)
18076365 Observational study of gene-disease association. (HuGE Navigator)
18080853 Observational study of gene-disease association. (HuGE Navigator)
18089344 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18095031 Observational study of gene-disease association. (HuGE Navigator)
18154909 Observational study of gene-disease association. (HuGE Navigator)
18156406 Observational study of gene-disease association. (HuGE Navigator)
18160589 Observational study of gene-disease association. (HuGE Navigator)
18160599 Observational study of gene-disease association. (HuGE Navigator)
18160602 Observational study of gene-disease association. (HuGE Navigator)
18160726 Observational study of gene-disease association. (HuGE Navigator)
18162478 Meta-analysis of gene-disease association. (HuGE Navigator)
18165967 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
18165972 Observational study of gene-disease association. (HuGE Navigator)
18167510 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18174236 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18176672 Observational study of gene-disease association. (HuGE Navigator)
18177869 Observational study of gene-disease association. (HuGE Navigator)
18180190 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18180959 Observational study of gene-disease association. (HuGE Navigator)
18186041 Observational study of gene-disease association. (HuGE Navigator)
18189241 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18191809 Observational study of gene-disease association. (HuGE Navigator)
18192106 Observational study of gene-disease association. (HuGE Navigator)
18192902 Observational study of gene-disease association. (HuGE Navigator)
18194124 Observational study of gene-disease association. (HuGE Navigator)
18195462 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
12413583 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12651974 Observational study of gene-disease association. (HuGE Navigator)
17436311 Observational study of gene-disease association. (HuGE Navigator)
17574963 Observational study of gene-disease association. (HuGE Navigator)
10791559 Meta-analysis and HuGE review of genotype prevalence, gene-disease association, gene-environment interaction, and healthcare-related. (HuGE Navigator)
11018168 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
11022077 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
11507973 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
11509014 Observational study of gene-disease association. (HuGE Navigator)
11522740 Observational study of gene-disease association. (HuGE Navigator)
11523237 Observational study of gene-disease association. (HuGE Navigator)
11531629 Observational study of gene-disease association. (HuGE Navigator)
11532106 Observational study of gene-disease association. (HuGE Navigator)
11555700 Observational study of gene-disease association. (HuGE Navigator)
11558898 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11562338 Observational study of gene-disease association. (HuGE Navigator)
11568114 Observational study of gene-disease association. (HuGE Navigator)
11569694 Observational study of gene-disease association. (HuGE Navigator)
11575217 Observational study of gene-disease association. (HuGE Navigator)
11583306 Observational study of gene-disease association. (HuGE Navigator)
11584084 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11589919 Observational study of gene-disease association. (HuGE Navigator)
11592436 Observational study of gene-disease association. (HuGE Navigator)
11592445 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11605019 Observational study of genotype prevalence. (HuGE Navigator)
11669477 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11672761 Observational study of genotype prevalence, gene-disease association, and gene-gene interaction. (HuGE Navigator)
11673296 Observational study of gene-disease association. (HuGE Navigator)
11680544 Observational study of genotype prevalence, gene-disease association, and gene-environment interaction. (HuGE Navigator)
11684547 Observational study of gene-gene interaction. (HuGE Navigator)
11692002 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11692165 Observational study of gene-disease association. (HuGE Navigator)
11696022 Observational study of gene-disease association. (HuGE Navigator)
11710708 Observational study of gene-environment interaction. (HuGE Navigator)
11711225 Observational study of gene-disease association. (HuGE Navigator)
11712321 Observational study of gene-disease association. (HuGE Navigator)
11714857 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11718053 Observational study of gene-disease association. (HuGE Navigator)
11721146 Observational study of gene-disease association. (HuGE Navigator)
11722155 Observational study of gene-disease association. (HuGE Navigator)
11734671 Observational study of gene-disease association. (HuGE Navigator)
11736945 Observational study of gene-disease association. (HuGE Navigator)
11738073 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
11738277 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
11739968 Observational study of gene-disease association. (HuGE Navigator)
11744407 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11744804 Observational study of gene-disease association. (HuGE Navigator)
11747974 Observational study of gene-disease association. (HuGE Navigator)
11749660 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11751445 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11758232 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
11768721 Observational study of gene-disease association. (HuGE Navigator)
11776159 Observational study of gene-disease association. (HuGE Navigator)
11781870 Observational study of genotype prevalence. (HuGE Navigator)
15046559 Observational study of gene-disease association. (HuGE Navigator)
15051606 Observational study of gene-disease association. (HuGE Navigator)
15053827 Observational study of gene-disease association. (HuGE Navigator)
15054400 Observational study of gene-disease association. (HuGE Navigator)
15054427 Observational study of gene-disease association. (HuGE Navigator)
15059157 Observational study of gene-disease association. (HuGE Navigator)
15059614 Observational study of gene-disease association. (HuGE Navigator)
15060097 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15068389 Observational study of gene-disease association. (HuGE Navigator)
15073531 Observational study of gene-disease association. (HuGE Navigator)
15073633 Observational study of genotype prevalence. (HuGE Navigator)
15075078 Observational study of gene-disease association. (HuGE Navigator)
15076187 Observational study of gene-disease association. (HuGE Navigator)
15082892 Observational study of gene-disease association. (HuGE Navigator)
15091001 Observational study of gene-disease association. (HuGE Navigator)
15096570 Observational study of genetic testing. (HuGE Navigator)
15103709 Observational study of gene-disease association. (HuGE Navigator)
15109703 Observational study of gene-disease association. (HuGE Navigator)
15110890 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15111988 Observational study of genotype prevalence. (HuGE Navigator)
15114595 Observational study of gene-disease association. (HuGE Navigator)
15114606 Observational study of genotype prevalence. (HuGE Navigator)
15117811 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15121372 Observational study of gene-disease association. (HuGE Navigator)
15123333 Observational study of gene-disease association. (HuGE Navigator)
15126006 Observational study of gene-disease association. (HuGE Navigator)
15126103 Observational study of genetic testing. (HuGE Navigator)
15130349 Observational study of gene-disease association. (HuGE Navigator)
15135249 Observational study of gene-disease association. (HuGE Navigator)
15135689 Observational study of gene-disease association. (HuGE Navigator)
15136061 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15138617 Clinical trial of gene-environment interaction. (HuGE Navigator)
15150439 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15151507 Observational study of gene-disease association. (HuGE Navigator)
15154859 Observational study of gene-disease association. (HuGE Navigator)
15159311 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15161007 Observational study of gene-disease association. (HuGE Navigator)
15163465 Observational study of gene-disease association. (HuGE Navigator)
15171737 Observational study of gene-disease association. (HuGE Navigator)
15192249 Observational study of gene-disease association. (HuGE Navigator)
15193960 Observational study of genotype prevalence. (HuGE Navigator)
15198953 Observational study of gene-disease association. (HuGE Navigator)
15201366 Observational study of gene-disease association. (HuGE Navigator)
15207432 Observational study of gene-disease association. (HuGE Navigator)
15210385 Observational study of gene-disease association. (HuGE Navigator)
15214944 Observational study of gene-disease association. (HuGE Navigator)
15216546 Observational study of gene-disease association. (HuGE Navigator)
15217535 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15219943 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16359859 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16363341 Observational study of gene-disease association. (HuGE Navigator)
16365025 Observational study of gene-disease association. (HuGE Navigator)
16365753 Observational study of gene-disease association. (HuGE Navigator)
16365871 Observational study of gene-disease association. (HuGE Navigator)
16369102 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16372906 Observational study of gene-disease association. (HuGE Navigator)
16373366 Observational study of gene-disease association. (HuGE Navigator)
16374229 Observational study of gene-disease association. (HuGE Navigator)
16375580 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16377929 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16379339 Observational study of gene-disease association. (HuGE Navigator)
16380544 Observational study of gene-environment interaction. (HuGE Navigator)
16380767 Observational study of gene-disease association. (HuGE Navigator)
16381636 Observational study of gene-disease association. (HuGE Navigator)
16389035 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16390701 Observational study of gene-disease association. (HuGE Navigator)
16391331 Observational study of gene-environment interaction. (HuGE Navigator)
16397167 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16399216 Observational study of gene-disease association. (HuGE Navigator)
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16407418 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16420563 Observational study of gene-disease association. (HuGE Navigator)
16422253 Observational study of gene-disease association. (HuGE Navigator)
16431900 Observational study of gene-disease association. (HuGE Navigator)
16439441 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16443328 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
16447238 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16447641 Observational study of gene-disease association. (HuGE Navigator)
16450127 Observational study of gene-disease association. (HuGE Navigator)
16450391 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16452733 Observational study of gene-disease association. (HuGE Navigator)
16456808 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16463153 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16464657 Observational study of gene-disease association. (HuGE Navigator)
16470725 Observational study of gene-disease association. (HuGE Navigator)
16472842 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
16484136 Observational study of gene-disease association. (HuGE Navigator)
16487909 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16489479 Observational study of gene-disease association. (HuGE Navigator)
16489563 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16514238 Observational study of gene-disease association. (HuGE Navigator)
16518429 Observational study of gene-disease association. (HuGE Navigator)
16521945 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16522920 Observational study of gene-disease association. (HuGE Navigator)
16522921 Observational study of gene-disease association. (HuGE Navigator)
14632302 Observational study of genotype prevalence. (HuGE Navigator)
18060320 Observational study of gene-disease association. (HuGE Navigator)
12654508 Observational study of gene-disease association. (HuGE Navigator)
12661370 Observational study of gene-disease association. (HuGE Navigator)
12667409 Observational study of gene-disease association. (HuGE Navigator)
12672676 Meta-analysis and HuGE review of genotype prevalence, gene-disease association, gene-gene interaction, gene-environment interaction, and healthcare-related. (HuGE Navigator)
12672677 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12673279 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12673582 Observational study of gene-disease association. (HuGE Navigator)
12674333 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12679134 Observational study of gene-disease association. (HuGE Navigator)
12681883 Observational study of gene-disease association. (HuGE Navigator)
12684695 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
12687650 Observational study of gene-disease association. (HuGE Navigator)
12689549 Observational study of gene-disease association. (HuGE Navigator)
12690011 Observational study of gene-environment interaction. (HuGE Navigator)
12690212 Observational study of gene-disease association. (HuGE Navigator)
12694231 Observational study of gene-disease association. (HuGE Navigator)
12705333 Observational study of gene-disease association. (HuGE Navigator)
12707953 Observational study of gene-disease association. (HuGE Navigator)
12709363 Observational study of genetic testing. (HuGE Navigator)
12713146 Observational study of gene-disease association. (HuGE Navigator)
12716294 Observational study of gene-disease association. (HuGE Navigator)
12718576 Observational study of genotype prevalence. (HuGE Navigator)
12724616 Observational study of gene-disease association. (HuGE Navigator)
12730409 Observational study of gene-environment interaction. (HuGE Navigator)
12730410 Observational study of gene-environment interaction. (HuGE Navigator)
12730722 Observational study of gene-disease association. (HuGE Navigator)
12738509 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
12738713 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
12747590 Observational study of genetic testing and healthcare-related. (HuGE Navigator)
12747593 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12747601 Observational study of gene-disease association. (HuGE Navigator)
12757770 Observational study of gene-disease association. (HuGE Navigator)
12766148 Observational study of gene-disease association. (HuGE Navigator)
12775885 Observational study of gene-disease association. (HuGE Navigator)
12776270 Observational study of gene-disease association. (HuGE Navigator)
12784029 Observational study of gene-disease association. (HuGE Navigator)
12784186 Observational study of gene-disease association. (HuGE Navigator)
12796225 Observational study of gene-disease association. (HuGE Navigator)
12797455 Observational study of gene-disease association. (HuGE Navigator)
12797595 Observational study of gene-disease association. (HuGE Navigator)
12801615 Observational study of gene-disease association. (HuGE Navigator)
12807760 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12816682 Observational study of gene-disease association. (HuGE Navigator)
12826168 Observational study of gene-disease association. (HuGE Navigator)
12827651 Observational study of gene-disease association. (HuGE Navigator)
12833177 Observational study of gene-disease association. (HuGE Navigator)
12844196 Observational study of gene-disease association. (HuGE Navigator)
12855225 Observational study of gene-disease association. (HuGE Navigator)
12855226 Observational study of gene-disease association. (HuGE Navigator)
17853476 Observational study of gene-disease association. (HuGE Navigator)
17438114 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17438654 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17439956 Observational study of gene-disease association. (HuGE Navigator)
17440589 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17449548 Observational study of gene-disease association. (HuGE Navigator)
17449906 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17450230 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17452895 Observational study of gene-disease association. (HuGE Navigator)
17453338 Observational study of gene-disease association. (HuGE Navigator)
17454207 Observational study of gene-disease association. (HuGE Navigator)
17454638 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17455988 Meta-analysis of gene-disease association. (HuGE Navigator)
17456624 Observational study of gene-disease association. (HuGE Navigator)
17456626 Observational study of genotype prevalence, gene-disease association, and gene-gene interaction. (HuGE Navigator)
17461517 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17469025 Observational study of gene-disease association. (HuGE Navigator)
17476281 Observational study of gene-disease association. (HuGE Navigator)
17479212 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17488658 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17491230 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
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17497026 Observational study of gene-disease association. (HuGE Navigator)
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17503006 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17503473 Observational study of gene-disease association. (HuGE Navigator)
17505678 Observational study of gene-disease association. (HuGE Navigator)
17512587 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17521309 Observational study of gene-disease association. (HuGE Navigator)
17522601 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17533396 Observational study of gene-disease association. (HuGE Navigator)
17537304 Observational study of gene-disease association. (HuGE Navigator)
17537363 Observational study of gene-disease association. (HuGE Navigator)
17543893 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17546637 Observational study of gene-disease association. (HuGE Navigator)
17548676 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17548696 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
17549067 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17551576 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17553479 Observational study of gene-disease association. (HuGE Navigator)
17558844 Observational study of gene-disease association. (HuGE Navigator)
17561949 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17563923 Observational study of gene-disease association. (HuGE Navigator)
17572411 Observational study of gene-disease association. (HuGE Navigator)
17573062 Observational study of gene-disease association. (HuGE Navigator)
17574929 Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
11801474 Observational study of gene-disease association. (HuGE Navigator)
11806787 Observational study of gene-disease association. (HuGE Navigator)
11807890 Observational study of gene-disease association. (HuGE Navigator)
11807892 Observational study of genotype prevalence. (HuGE Navigator)
11813127 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
11815318 Clinical trial of gene-environment interaction. (HuGE Navigator)
11821270 Observational study of gene-disease association. (HuGE Navigator)
11823591 Observational study of gene-disease association. (HuGE Navigator)
11828266 Observational study of gene-disease association. (HuGE Navigator)
11843038 Observational study of gene-disease association. (HuGE Navigator)
11851723 Observational study of gene-disease association. (HuGE Navigator)
11860783 Observational study of gene-disease association. (HuGE Navigator)
11860891 Observational study of gene-disease association. (HuGE Navigator)
11870335 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11872199 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
11872884 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
11880124 Observational study of gene-disease association. (HuGE Navigator)
11889073 Observational study of gene-disease association. (HuGE Navigator)
11904614 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11913566 Observational study of gene-disease association. (HuGE Navigator)
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11927833 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11928564 Observational study of gene-disease association. (HuGE Navigator)
11929966 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11935469 Observational study of gene-disease association. (HuGE Navigator)
11938441 Observational study of gene-disease association. (HuGE Navigator)
11940092 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
11943942 Observational study of gene-disease association. (HuGE Navigator)
11947914 Observational study of gene-disease association. (HuGE Navigator)
11950428 Observational study of gene-disease association. (HuGE Navigator)
11953142 Observational study of gene-disease association. (HuGE Navigator)
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11979347 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
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17200768 Observational study and meta-analysis of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
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17714520 Meta-analysis of gene-disease association. (HuGE Navigator)
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17726226 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
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17805475 Meta-analysis of gene-disease association. (HuGE Navigator)
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17260091 MTHFR variant homozygous allele is associated with breast cancer
18225686 A FV Leiden/ methylenetetrahydrofolate reductase (MTHFR) T677T double genotype increases the risk for placental abruption
17604826 There is a dynamic regulation of MTHFR gene expression during the arterialization process of human saphenous vein grafts resulting in lower levels of gene expression when in an arterial hemodynamic condition.
17505678 The TT genotype is associated with coronary artery obstruction greater than 95% and the presence of two affected arteries.
17512587 observed an association between 677TT variant and survival in a subset of ALL patients homogenously treated with MTX-based maintenance and confirmed the role of 677TT variant on toxicity during MTX treatment
17543893 Increased MTHFR 677T allele load confers risk for negative symptoms in schizophrenia, while reducing severity of positive symptoms.
18098291 Common variation in MTHFR and TYMS genes may be associated with RCC risk, particularly when vegetable intake is low.
18214047 MTHFR-A1298C polymorphism might be associated with liver toxicity in patients receiving allogeneic hematopoietic stem cell transplantation.
18095031 the present study highly suggest that GSTP1, MDR1, and MTHFR genotypes could be prognostic factors for Taiwanese patients with breast cancer.
17725378 In this cohort of elderly whites, the MTHFR C677T variant interacts with dietary riboflavin intake to influence fracture risk in women.
18043712 No evidence of association between a functional polymorphism in the MTHFR gene and childhood-onset mood disorders.
18220649 Possibility of personalized medicine for diabetes mellitus based on an understanding of MTHFR gene polymorphism and its ramifications in diabeti retinopaathy. (REVIEW]
17395259 No differences of these polymorphisms were found between ALL cells and normal blood cells, indicating an ethnic rather than leukemic origin.
18160599 The authors did not find any significant role of factor V Leiden Hong Kong/Cambridge mutation and MTHFR polymorphism in the development of recurrent abortion.
18220034 No difference in HC concentration in plasma was observed in CMPD carriers of homo- or heteroxygous mutation of C667T gene or CMPD patients without the mutation.
17221112 A lack of correlation between C677T mutation and homocysteine level suggests that environmental factors and others genetic factors seem to exert more influence on homocysteine level in coronary atherosclerotic disease.
18089344 MTHFR polymorphisms affect homocysteine levels in kidney transplantation, which can be reduced by folic acid and vitamin B administration.
17805475 although there is some evidence of association between MTHFR C677T gene polymorphism and diabetic nephropathy, the above findings reinforce the need for further and more rigorous association studies( Meta-Analysis)
18160726 MTHFR C677T polymorphism influences the folate pattern in whole blood.
17726226 Data suggest that the combination of homozygous MTHFR 677T and angiotensin II type-1 receptor 1166C variants confers the risk of small-vessel-associated ischemic stroke.
18057532 report on the possible genetic association between Down syndrome and methylenetetrahydrofolate reductase (MTHFR) 1298A/C genotypes among Egyptians
17581676 Results suggest that the alterations of folate metabolism related to MTHFR, MTR and MTRR polymorphisms are not involved in clefting in South Brazil.
17993766 These findings suggest that in obese subjects, homocysteine cycle efficiency is impaired by MTHFR, MTR, and MTRR inability to supply methyl-group donors, providing evidence that MTHFR, MTR, and MTRR gene polymorphisms are genetic risk factors for obesity.
17708272 study did not reveal any association between inflammatory bowel disease and MTHFR mutations interfere with neither disease manifestations nor the thrombotic complications
17970089 study concludes that The MTHFR C677T and A1298C polymorphisms are not significant risk factors in adult acute leukemia in the Korean population
17957761 In Haryana, India Jats the methylenetetrahydrofolate reductase T allele is more frequent than in Ahirs; the Jats shows a significant deviation from Hardy-Weinberg equilibrium with respect to C677T mutation
17221000 Our data confirms the association between increased plasma Hcy concentration and AD and suggests that neither C677T nor A1298C MTHFR polymorphisms contributed to genetic susceptibility for AD in elderly individuals in the Northeast of Brazil.
17726486 The significant association between C677T polymorphism and hypertension/hypertension-in-pregnancy suggested that this polymorphism was one independent risk factor of hypertension.
17618486 An association of single nucleotide polymorphism genotype and neural tube defects in people of European descent.
18156406 These data showed that the folate RDA is not adequate for men of Mexican descent, particularly for those with the MTHFR 677TT genotype, and demonstrated a lack of influence of choline intake on the folate status variables measured in this study.
18075008 The researchers found that the C677T MTHFR mutation is associated with an increased risk of coronary artery disease in a sex-dependent fashion in Brazilians.
17853476 The risk of having a child with congenital malformation or FACS was three to four times higher for mothers who were MTHFR 677TT homozygotes compared with MTHFR 677CC homozygotes
17966140 study concluded that there was no influence of mutations or polymorphisms in methylenetetrahydrofolate reductase gene on homocysteine levels in chronic renal failure dialysis patients
18154909 Preliminary data imply a strong relationship between MTHFR polymorphisms and the inattentive symptoms of ADHD in survivors of childhood ALL.
17354258 MTHFR gene single nucleotide polymorphism is not associated with the development of diabetic nephropathy in Turkish type 2 diabetic patients.
17097210 No correlation was observed between pre-eclampsia and presence of methylenetetrahydrofolate reductase (MTHFR) C677T mutations in Brazilian women.
17855693 the C677T polymorphism modifies the age at onset of colorectal cancer in Caucasian Lynch syndrome subjects with the 677T allele having a protective effect
17962595 Migraine may act as mediator in the methylenetetrahydrofolate reductase-ischemic stroke pathway
18074687 Both MTHFR 677C-->T polymorphism and higher T allele frequency have significant associations with atlantoaxial dislocation.
17914182 There is no any significant association of combined C677T and A1298C MTHFR polymorphisms with an increased risk for hyperhomocysteinemia in PD patients.
17418558 MTHFR C677T genotype is the dominant determinant of nonmethylfolate accumulation in RBCs. In addition, high total folate status may contribute to minor to moderate nonmethylfolate accumulation in MTHFR CC and CT subjects.
17972183 MTHFR genotype appears to modulate an individual's susceptibility to gastric cancer, particularly when combined with cigarette smoking and a low intake of fruit and vegetables.
17602711 the protective effect of the homozygous variant TT form of the MTHFR genotype (C677T) on the risk of colorectal cancer seems to be modified by the level of methyl diets
17537304 The genetic polymorphisms of MTHFR C677T are associated with unexplained recurrent early spontanous abortion. It might indicate a genetic influence on pathogenesis of URESA, and have no significance in URESA.
16077191 Determine associations between age, MTHFR/PON1 genotype and risk of coronary artery disease.
17638709 study provides evidence that MTHFR C677T genotype is associated with cognitive test performance in a large cohort of older women
17503473 no evidence that transmission of the MTHFR 677T allele is associated with schizophrenia risk.
17712717 study concludes that the C677T polymorphism of the MTHFR gene does not appear to be associated with the overall risk of osteoporotic fractures
17704619 RLP-cholesterol is better associated with, APOE genotype than triglyceride and the effect of the T allele on MTHFR polymorphism (C667T) homocysteine levels is more prominent in men than in women among Japanese
17085942 In the North Indian population, the 677C-->T allele of the MTHFR gene may be associated with the occurrence of a lower type of neural tube defects. There is a possible differential role of thermolabile MTHFR at different sites of neural tube closure.
17974190 Significant prevalence of C677T genetic variant in MTHFR was found in women with recurrent early pregnancy loss compared with controls.
17333388 MTHFR 677T and 1298C alleles and co-occurrence of MTHFR 677 CT/MTHFR 1298 CC genotypes are associated with increased risk of hypertension and MTHFR 1298 CC genotype is associated with higher homocysteine levels.
16951158 Inadequate methyl donor production from MTHFR deficiency promotes genomic hypomethylation and further genomic instability in brain glioblastoma.
17966954 Results revealed that the MTHFR C677T polymorphism could significantly influence age at onset of Parkinson's disease (PD) in Chinese population, but neither as a genetic susceptibility nor as a predictor of levodopa-induced adverse effects in PD.
17711493 The MTHFR C677T polymorphism could thus have an ambiguous role in migraine.
17228344 MTHFR genotype, plasma folate, vitamin B6 & vitamin B12 & age were significantly correlated to plasma homocysteine; MTHFR 677TT-related carotid atherosclerosis was only identified in healthy elderly subjects with lower level of plasma folate & vitamin B12
17573062 Data indicate the C677T MTHFR polymorphism does not significantly contribute to the genetic susceptibility to breast and prostate cancer, while show some evidence for possible genetic contribution to the development of head and neck carcinoma.
17618615 Results show that homozygosity for the T allele of MTHFR was more frequent in diabetics than in healthy subjects (12.8% vs. 7.2%) and it was associated with higher tHcy levels.
17904970 In this population, neither heterozygosity nor homozygosity for the 677C-->T and 1298A-->C variants in MTHFR was associated with placental abruption.
16380767 MTHFR C677T variant mildly influences cardiovascular disease in Eastern Saudi Arabia
17510921 The results of this study do not show any significant association between the MTHFR C677T polymorphism and congenital heasrt defects.
17659576 This study supports the hypothesis that reduced MTHFR activity and enhanced TYMS activity, both of which are essential elements in minimizing uracil misincorporation into DNA, may protect against the development of hepatocellular carcinoma.
17911197 MTHFR C677T and A1298C were equally distributed in the thrombosis patient group compared with the control group.
17670851 G20210A mutation was not associated with an increases risk for cerebrovascular accidents.
17891601 Neither at the gene level nor at the genotype level was a significant association between MTHFR 677T and mucositis found.
17115239 Review concludes that the common C677T polymorphism of the MTHFR gene is associated with small differences in bone mineral density, at least in women.
17058088 twi case of ependymoma associated with Klinefelter's Syndrome had deficit of methyltetrahydrofolate reductase (MTHFR)
16941173 Patients with microsatellite instability tumors had higher frequency of TT MTHFR C627T polymorphisms.
17063264 functional polymorphisms in the MTHFR gene modify the risk of breast and may potentially alter the risk of ovarian cancer in women with BRCA1,an inherited predisposition
17684410 study found that functional polymorphisms in MTHFR and thymidylate synthase were significantly associated with increased risk of esophageal squamous cell carcinoma, gastric cardia carcinoma, and pancreatic carcinoma
17111187 The methylenetetrahydrofolate reductase (MTHFR) gene, involved in folate metabolism, is polymorphic in humans.
17438114 Genetic variants of MTHFD and plasma homocysteine levels are associated with risk of gastric cancer and modulated by genotypes of MTHFR in a Chinese population.
17028897 Patients at high risk of developing hepatic toxicity and with a poor likelihood of survival could be selected by genotyping MTHFR C677T before allogeneic stem cell transplantation.
17627684 We found a non-significant increased risk of being a homozygous MTHFR C677T carrier in the placental abruption group.
17625574 MTHFR667 and MTHFR1298 mutations do not increase the risk of umbilical catheter associated thrombosis in our NICU population.
17621650 The polymorphism A1298C-MTHFR is not associated with NTDs, except for mothers, suggesting only a maternal association with having neural tube defect-affected offspring in the Yucatan population.
16906320 presence of the MTHFR 677T allele was associated with the occurrence of vascular complications in sickle cell disease (SCD)
17301815 The advantage of de novo purine synthesis found in the MTHFR TT genotype may account for the protective effect of MTHFR in hematological malignancies.
17572411 MTHFR A1298C polyymorphism may modulate folliculogenesis.
17691219 studied the polymorphisms of mthfr no significant differences in intensity of turnover of circulating thiols between AD and PD patients.
17151928 The MTHFR 677T allele confers an increased risk of breast cancer in BRCA1 carriers. The MTHFR 1298C allele confers an increased risk of breast cancer in sporadic cases.
17284634 Betaine may thus be an important one-carbon source, particularly in MTHFR C-T genotype subjects with inadequate B-vitamin status.
17584018 GSTP1 and MTHFR genotypes may be consider relevant and independent factors of toxicity in adjuvant anthracycline-based treatment of breast cancer.
17704422 Association of methylenetetrahydrofolate reductase gene polymorphisms and sex-specific survival in patients with metastatic colon cancer
17449548 Coexistence of homozygosity for the C677T mutation and B12 deficiency is associated with endothelial dysfunction and can be corrected with vitamin B12 and folic acid treatment.
17627388 Multiple polymorphisms of the methylenetetrahydrofolate reductase gene are documented, and some are associated with decreased enzyme activity.
16381636 The genetic mutation of MTHFR C667T is possibly an important mechanism of hyperhomocysteinemia in liver cirrhosis. The level of plasm homocysteine may be an eary indicator for liver cirrhosis.
16846676 in Black South African population, frequency of MTHFR 677 C-T polymorphism did not differ between patients with abruptio placentae and controls
17476281 a significant association was observed between the MTHFR haplotype (single nucleotide polymorphisms 677 and 1298) and risk of developing therapy-related-MDS/AML in the breast cancer patients group and cyclophosphamide-treated hematological disease group
17666612 In a prospective cohort study, a significant difference in MTHFR C677T polymorphism genotype distributions was observed in women with small for gestational age infants compared with controls.
17641264 This report describe 2 female cousins with neonatal stroke. One was heterozygous for the plasminogen activator inhibitor-1 4G variant and compound heterozygous for the A1298C and C677T methylenetetrahydrofolate reductase mutations.
12011160 Maternal MTHFR genotype contributes to the risk of non-syndromic cleft lip and palate
14644077 The homozygous C677T mutation in the MTHFR gene is associated with multiple small-artery occlusions.
12417280 The C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene results in reduced MTHFR enzyme activity and reduced methylation of homocysteine to methionine resulting in mild hyperhomocysteinaemia
15894672 This study corroborates previous findings of inverse association of the MTHFR 677TT genotype with colorectal cancer, especially at high levels of folate and low levels of ethanol intake. The effect may be specific to advanced colon cancer.
11880124 MTHFR gene mutations may affect vitamin B12 and homocysteine metabolism in Brazilian children with neural tube defects
16084002 Association of the C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene with schizophrenia: association is significant in men but not in women.
16533336 In patients of advanced reproductive age, the MTHFR 677C>T mutation affects ovarian responsiveness.
16930349 Homozygous methylenetetrahydrofolate reductase C677T mutation in a woman with spinal cord infarction.
17156840 MTHFR polymorphism is associated with chronic myelogenous leukemia
12083967 clinical consequences of polymorphism (REVIEW)
15063140 single nucleotide polymorphism in MTHFR gene is associated with Nasopharyngeal Neoplasms
15082892 mutation of the MTHFR gene is implied by the study results to be a risk factor of hyperuricemia in elderly Korean men.
12138370 The polymorphisms C677T and A1298C of MTHFR and fasting plasma homocysteine levels do not seem to be significant risk factors for venous thromboembolic disease.
12430180 Relative to compound wild-type subjects, compound heterozygotes had moderately reduced risk (OR = 0.47, 95% CI 0.11-1.92) and homozygote variants (677TT and/or 1298CC) greater reduced risk (OR = 0.26, 95% CI 0.07-0.96)
15525878 C677T mutation is frequent in diabetic patients with hyperhomocysteinaemia and could contribute, besides non genetic factors, to increased levels of homocysteine.
15569990 Methylenetetrahydrofolate reductase may have a role in relapse and progression of chronic myelogenous leukemia
16280279 Patients with hypertension and the 677TT genotype showed significantly higher homocysteine levels as compared to individuals having CC and CT.
16306100 polymorphisma in the MTHFR gene may play an important role in determing the erythrocyte thiopurine methyltransferase phenotype
16372906 Contrary to previously described evidence the A1298C polymorphism in the MTHFR gene does not appear to modulate age of onset of Huntington disease patients
16682831 hyperhomocysteinemia and the common C677T variant of methylene tetrahydrofolate reductase (MTHFR) gene are not associated with metabolic syndrome in Type 2 diabetic subjects
16870553 (MTHFR) T677 variant had a significantly lower frequency of weeks with high-grade hematologic and liver toxicity during consolidation and maintenance treatment of acute lymphocytic leukemia in children.
17452895 study did not find a statistically significant association of SNP factor V Leiden G1691A and MTHFR C677T with renal graft survival; Prothrombin G20210A resulted in a significant association that was not sustained after Bonferroni correction
17491230 Mutations in the MTHFR gene are associated with elevated levels of homocysteine.
12958073 protective role of MTHFR gene polymorphisms (C677T and A1298C) in acute lymphoblastic leukemia
17074966 This meta-analysis suggests an association between the MTHFR C677T variant and the risk of developing depression, schizophrenia, and bipolar disorder. The researchers found no such associations with the A1298C variant.
17087956 We propose that the effect of the MTHFR genotypes on increasing risk of adenoma recurrence in the presence of a low folate status is through their increase in homocysteine concentrations.
12766148 No association between the MTHFR gene polymorphism and diabetic retinopathy in type 2 diabetic patients without overt nephropathy
15046559 The distribution of MTHFR genotypes did not differ between Slovak-Romanies and Slovak-Caucasians, and no effect of MTHFR genotypes on homocysteine levels was observed in the Romanies, but TT homozygosity increased homocysteine levels in the Caucasians.
11938441 high prevalence of mutated MTHFR genotypes in spontaneously aborted embryos
15130349 The mutations of methylenetetrahydrofolate reductase C677T and A1298C play a role in the mechanism of unexplained recurrent spontaneous abortion.
17113927 In conclusion, the C677T and A1298C polymorphisms of the MTHFR gene are genetic risk factors for hamorrhagic and ischemic stroke respectively, independent of other atherothrombotic risk factors.
17174622 MTHFR C677T polymorphism is an independent predictor of fracture risk, although it only had a weak effect on bone mineral density
12471611 MTHFR polymorphism is associated with marked mtx-induced hyperhomocysteinemia in ovarian cancer
12746418 Maternal 677CT/1298AC genotype as a risk factor for cleft lip
12801615 MTHFR TT genotype was associated with hyperhomocysteinemia, but not with significant coronary artery disease.
15886665 methylenetetrahydrofolate reductase C677T mutation is not associated with chronic limb ischemia.
15837084 show an association between markers of systemic inflammation in healthy subjects with MTHFR C677T genotype
16377929 The mutation of C677T MTHFR was not independently associated with the prevalence of hypertension or blood pressure levels although serum uric acid was in Japanese men.
11947914 Homocysteine (tHcy) levels and methylenetetrahydrofolate reductase (MTHFR) genotype are primary risk factors for coronary heart disease (CHD).
12107847 MTHFR may be required for tumor survival. Antisense inhibition of MTHFR reduces survival of methionine-dependent tumor cell lines.
15612980 SNPs in this enzyme affects homocysteine-regulating genes and may be important determinants of vitamin metabolism in heart transplantation.
15613145 C677T MTHFR mutation is strongly associated with arterial stroke especially in young adults.
16169307 Significant skeletal effects of this common polymorphism (MTHFR c.677C>T)were present at the lumbar spine in men at the age of 25 years.
12370778 multiple transcription start sites and alternative splicing
16365753 MTHFR mutation is a minor contributing factor in oncogenesis in the oral region, in conjunction with low dietary uptake of folate.
16365871 Risk of migraineurs with aura is associated with MTHFR C674T homozygosity, independent of other cardiovascular risk factors.
16641680 The folate supplement may be beneficial to some schizophrenic patients with homocysteinemia due to the genetic defect of methylenetetrahydrofolate reductase.
15002923 C677T mutation at the MTHFR gene and deficiencies of folic acid and vitamin B-12 may account for elevation of total homocysteine (tHcy)
15003888 These results do not support the suggestion that populations carrying different genotypes of the two MTHFR polymorphisms, C677T and A1298C, have a different susceptibility to ALL, at least in the Mediterranean area.
16987799 the A1298C, but not C677T, mutation of methylenetetrahydrofolate reductase is associated with the genotype of sickle cell disease
12496052 The variation at MTHFR codon 1298, maybe more important for colon cancer than variation at codon 677.
16927418 MTHFR C677T polymorphism may not be important in an individual's susceptibility to gastric and colorectal cancer in Turkey and may not be a useful marker for identifying patients at high risk of developing gastric and colorectal cancer.
16936384 MTHFR gene polymorphism was found in one-third of patients with ischemic stroke and was insignificantly associated with higher frequency of elevated Hcy in India.
12574198 in polycystic ovary syndrome women, the serum Hcy levels are normal, and the C677T polymorphism of MTHFR does not influence the Hcy levels like in controls.
17245555 folate intake, low methyl donor status, and MTHFR polymorphisms may play independent roles in the etiology of rectal cancer
17287626 hyperhomocysteinemia and compound heterozygous state for MTHFR are independent risk factors for DVT among South Indians.
15607533 Methylenetetrahydrofolate reductase polymorphism associated with susceptibility to coronary heart disease in Chinese type 2 diabetic patients
14746952 The mutant MTHFR 677T allele shows relatively high prevalence in different ethnic groups and potentially associated with preeclampsia.
16108833 Individuals with the variant alleles MTHFR 677T had a decreased risk of colorectal adenoma, suggesting that folate inhibits the growth of colorectal adenomas.
12081832 methylenetetrahydrofolate reductase TT genotype homozygotes require higher folate intakes to achieve similar homocysteine concentrations
14572619 Elevated Hcy levels and, in line with this finding, homozygosity for the 677C-->T mutation in the MTHFR gene were not associated with an increased risk for schizophrenia.
14607573 C677T methylenetetrahydrofolate reductase polymorphism not risk factor for male factor subfertility. Sperm concentration in heterozygotes and homozygotes did not significantly benefit from folic acid and zinc sulfate.
17488658 NHL patients with MTHFR variants C677T & A1298C showed different survival rates, susceptibilities to side effects & responses to methotrexate-containing regimens. MTHFR may affect the effectiveness & toxicity of methotrexate.
15117811 Polymorphisms of methylenetetrahydrofolate reductase (NADPH) is associated wtih bladder cancer
17365577 MTHFR is involved in arsenic metabolism in humans, and polymorphisms in the gene may play a role in susceptibility to arsenic-induced cancer
17389614 MTHFR variant cytosine677thymine is associated with a moderately increased risk of lung cancer.
11872884 A significant association between the MTHFR TT genotype and spontaneous cervical artery dissection was observed
12674333 A common methylenetetrahydrofolate reductase (C677T) polymorphism is associated with low bone mineral density and increased fracture incidence after menopause: longitudinal data from the Danish osteoporosis prevention study.
12687650 plasma total homocysteine is associated with sex, age, and MTHFR genotype
12738713 MTHFR polymorphism is associated with tumor response to fluoropyrimidine-based chemotherapy for advanced colorectal neoplasms
12964809 MTHFR 677TTor 1298CC genotypes are much rarer in Africans than in Caucasians; the 677TT low frequency may be related to the high effect of this mutation on homocysteine metabolism in the environmental conditions of the Sub-Saharan Africa region
13678724 A strong association of MTHFR polymorphisms and invasive cervical cancer is demonstrated using family-based controls and a transmission/disequilibrium test.
14717963 association between hyperhomocysteinemia, low folate, MTHFR 677TT mutation and risk of myocardial infarct
14767907 MTHFR C677T gene polymorphism is a genetic risk factor for URSA.
15353918 demonstrate a strong association of hyperhomocysteinemia and homozygosity of the MTHFR C677T, but not FV-Leiden or PT G20210A, mutations with confirmed CAD, and also suggest a potential role for factor V-Leiden in MTHFR C677T carriers.
15354395 Determination of MTHFR polymorphisms and CAG repeat lengths enables screening for subjects with putative early Huntington's disease onset.
15514969 Polymorphisms in the folate metabolic pathway were associated with a lower likelihood of Cervical intrepithelial neoplsia.
12649066 Combination of the cystathionine-beta-synthase repeats with a MTHFR polymorphism revealed an additional increase in homocysteine levels in 18-18 individuals compared with 17-18 peers within subjects homozygous mutant for the MTHFR polymorphism
16244782 The fact that MTHFR A1298C polymorphism is significantly associated with homocysteine levels and that the CC genotype is present at a higher frequency in the Indian population makes it relevant in terms of its potential impact on hyperhomocysteinemia.
12540022 The exclusive pattern of MTHFR allele loss in cases of LOH, suggest that functional MTHFR activity within a tumor might play an important role in the survival and progression of a colonic neoplasm.
12810988 Analysis of data for the studied population does not prove the influence of mutations 677C-->T and 1298A-->C of MTHFR gene on NTDs (neural tube defects).
15289817 Results exclude a major role for both C66T and A1298C variants of the MTHFR gene in conferring susceptibility to schizophrenia in two racially distinct populations.
16234002 The methylenetetrahydrofolate reductase (MTHFR) and TS polymorphisms and genetic determinants for developing pancratic cancer
16399216 Subjects with the MTHFR 677TT genotype tended to perform better on cognitive tasks than CC/CT subjects.
16754204 Methylenetetrahydrofolate reductase gene is not associated with disease in cohorts of pseudoexfoliation glaucoma and primary open-angle glaucoma patients
16828193 Single nucleotide polymorphisms are a risk factor for type 2 diabetes in a Tunisian population.
16867914 MTHFR C677T polymorphism does not have a major role in the development of preeclampsia or placental abruption in the Finnish population.
16936070 We found that children who carry the 677T variant of the MTHFR gene are at decreased risk of clubfoot.
11929966 A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.
17300365 This study showed that genetically induced hyper-homocysteinemia (MTHFR C677T genotype) may favor the neuronal factors predisposing to migraine. It does not influence the presence of subclinical vascular brain lesions linked with increased risk of stroke.
17334320 All patients with ISSNHL should undergo a hematologic investigation of inherited and acquired prothrombotic factors, including MTHFR polymorphisms to identify a subset of patients at high risk of recurrent HL.
17334642 The major genetic impact on homocysteine concentrations is attributable to the MTHFR 677C>T polymorphism.
17503006 The MTHFR 677 C/T genotype was associated with an increased risk of primary liver cancer in a Chinese population. The polymorphism of MTHFR 677 might modify the effects of raw water drinking on the risk of primary hepatocellular carcinoma.
15829163 The incidences of both homozygous and heterozygous MTHFR gene mutations in cerebral ischemia (26 and 43%) and in cerebral hemorrhage (25 and 60%) were significantly higher than those in the controls (8 and 25%).
12923155 Embryos with combined MTHFR 677TT and TC 776CG or 776GG genotypes; genotypes individually associated with impaired homocysteine metabolism in adults, are at increased risk for spontaneous abortion compared with embryos with only one of these genotypes.
12411076 the polymorphisms of MTHFR C677T was associated with risk of developing stomach cancer.
12684695 Results suggest that the genotyping for thymidylate synthase and methylenetetrahydrofolate reductase polymorphisms may be a useful indicator in determining the appropriate dose of methotrexate in patients with rheumatoid arthritis.
14688536 C677T polymorphic patients show increasd adverse effects to methotrexate in stem cell transplantation.
14704292 preliminary investigation suggests that methylenetetrahydrofolate reductase C677T polymorphism and riboflavin affect genome instability; however, the effect is relatively small compared with that of folic acid
15041282 evidence for homozygous C677T mutation in the MTHFR gene as risk factor for ischemic cerebralvascular disease in young women, pregnant or taking oral contraceptives
15214944 NO concentration but not the polymorphism of MTHFR and eNOS gene and hyperhomocysteinemia are associated with recurrent pregnancy loss in Japanese
15231206 There was a coordinated effect between methylenetetrahydrofolate reductase 1298 genotypes and habits of smoking, alcohol drinking and tea consumption in the development of esophageal cancer.
15369724 MTHFR gene polymorphism is associated with development of chronic allograft nephropathy
15469701 This study was designed to investigate, in the Turkish population, the association of methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism and left ventricular hypertrophy (LVH) in patients with type II diabetes mellitus.
15618240 In end-stage renal disease, MTHFR C677T polymorphisms were not associated with cardiovascular disease or mortality.
15686674 In renal transplant recipients, presence of the allelic variants for MTHFR polymorphisms might play a role as an additional risk factor for chronic allograft nephropathy.
15840047 Higher folate concentrations in kidney transplant recipients with MTHFR 1793GA or 1793AA and markedly higher concentrations of vitamin B(12) in patients with combined MTHFR 1793G>A and 1298A>C mutations may contribute to a survival advantage.
15922487 CBS, MTHFR, and SLC19a1 are involved in metabolism of folate and lung cancer risk in China
12204804 The mutation of MTHFR gene can be modified by dietary supplement of vitamin B12 as well as folate to reduce homocysteine levels of atherosclerotic patients.
15514263 findings indicate that when the homozygous variant for the MTHFR 677CT polymorphism coexists with the MTRR 66 AG genotype, plasma homocysteine is significantly elevated relative to the other genotype groups
15546509 individuals with the MTHFR 677TT genotype have a decreased risk of colorectal cancer in the absence of folate depletion, suggesting a protective role of folate by ensuring a sufficient thymidylate pool for DNA synthesis.
15351230 MTHFR gene polymorphisms is associated with acute myocardial infarction
15973722 TPMT, ITPA, and MTHFR genotypes do not predict adverse drug reactions, including bone marrow suppression, in liver transplant patients.
14594111 our results do not support an association between the methylenetetrahydrofolate reductase 677T allele and male infertility in Italy
15097012 There is little evidence of the child's MTHFR alleles on the risk of developing preeclampsia.
15226189 MTHFR C677T homozygosity with hyperhomocysteinemia is not associated with ischemic cardiovascular disease and venous thromboembolism
12796044 These findings suggest a possible role of MTHFR and folic acid in the causation of orofacial clefts, but the strength and direction of these effects remain to be clarified.
15929053 the TT variant of the methylenetetrahydrofolate reductase C677T polymorphism is associated with an increased risk for Parkinson's disease in smokers
15893594 The ACE D allele confers a weak independent risk to migraine susceptibility and also appears to act in combination with the C677T variant in the MTHFR gene to confer a stronger influence on the disease.
12032275 Methylenetetrahydrofolate reductase polymorphism in the etiology of down syndrome.
12080391 results do not support the presence of an increased risk of Down syndrome in mothers carriers of the T allele in the Italian population.
12453860 MTHFR C677T polymorhism may indicate the need to reduce the dose of methotrexate during prolonged administration to prevent toxicity.
12442281 The results of this study demonstrate that the MTHFR 677T alleles are associated with a common haplotype most likely due to a founder effect and that the 677T haplotype was the same in the healthy and the thrombophilic German subjects.
12529699 Absence of association of fetal MTHFR C677T polymorphism with prenatal Down syndrome pregnancies
14742985 Genotypes of PAI-1 4G/5G and MTHFR C677T or plasma concentrations of PAI-1 had no effect on the incidence of ONFH in Japanese subjects.
16234003 Deficient MTHFR function due to loss of an MTHFR allele by an evolving neoplasm might, by promoting chromosomal losses, accelerate cancer development
16375580 In MTHFR C677T carriers, acetylcholinesterase activity was significantly higher
16417907 MTHFR gene might be the key thrombophilia gene conferring susceptibility to recurrent spontaneous abortion in Chinese women.
16621645 Two common polymorphisms in MTHFR change a metabolic phenotype in opposite directions suggesting that their cancer protective associations are by different mechanisms.
16634455 The synergistic effect between the two MTHFR mutations may represent a new genetic stoke risk factor.
16777985 methylenetetrahydrofolate reductase polymorphisms have a role in breast cancer susceptibility
16787708 The frequency of allele C677T of MTHFR gene did not differ between Parkinson disease patients and controls.
17010581 Mutation of 5-MTHFR C677T contributes to the higher uric acid levels in both males and females and may be a risk factor for hyperuricemia
17149733 Variants of MTHFR genes are possible risk factors for several mental retardation.
17074326 The MTHFR C677T mutation is not a genetic risk factor for URPL except in a Chinese population.
17074544 White carriers of SHMT1(1420)T or MTRR(66)A had an increased risk of spontaneous preterm birth.
17156138 Some differences were observed among cases and controls in the prevalence of MTHFR C677T (decrease in mutant allele carriership in UC), these did not explain an excess risk of thrombosis.
17171786 The 677CT genotype showed a non-significant higher risk for gastric cancer as compared with the 677CC genotype
17264399 1793G-A and 677C-T MTHFR polymorphisms did not contribute to the prediction of clinically defined CAD in Caucasians.
17344026 MTHFR C677T genotype contributes to certain executive function deficits in schizophrenia
17372834 Forty-eight individuals (84%) were homozygous for 677 CC. Of these individuals, 18 (37.5%) had >/=1 colorectal polyps, whereas 30 (62.5%) had no polyps. Nine individuals were heterozygous for 677 CT, and 4 (44%) of these individuals had colon polyps.
17439956 Maternal homozygosity for the 677T allele of the MTHFR gene is associated with anencephaly.
17457696 Sequence alteration c.677C>T combined with Severe MTHFR mutations in the compound heterozygous state may lead to moderate biochemical and clinical abnormalities.
17627246 Individuals carrying MTHFR 677T allele had marked increase in risk of squamous cell carcinoma after adjustment for age, ender, skin type, sun exposure score, and immunosuppression duration.
17622358 677 C-->T polymorphism of MTHFR was not related to prognosis in patients after an acute coronary syndrome.
12097662 Vitamin B-12 status is inversely associated with plasma homocysteine in young women with C677T and/or A1298C methylenetetrahydrofolate reductase polymorphisms.
12730722 findings do not support a role for the 1298A-->C polymorphism in neural tube defects (OR 0.85 (95% CI 0.49-1.47), p= 0.55), nor do we observe a combined effect with the 677C-->T polymorphism
12827651 There are associations between the genotypes of this enzyme and the risk of developing acute leukemia.
12928053 The common methylenetetrahydrofolate reductase C677-->T gene polymorphism was investigated as a risk factor for Alzheimer's disease. The MTHFR C677-->T and polymorphism did not appear to confer an added risk for AD.
12927690 frequency of C677T methylenetetrahydrofolate reductase (MTHFR) mutation in healthy Croatian volunteers and in patients with atherosclerosis
11744804 Results indicate that MTHFR polymorphism may be a risk factor for CVD in patients on hemodialysis, and MTHFR VV genotype and gender may be strong determinants of the plasma homocysteine level.
12400059 An allele of this enzyme is prefertially transmitted to infants with Down syndrome: implications for a survival advantage
12730409 A reductase 677C-->T variant modulates folate status response to controlled folate intakes in young women.
12730410 The interaction between MTHFR 677 C-->T genotype and folate status is a determinant of coronary atherosclerosis risk.
12015164 The C677T mutation in the methylenetetrahydrofolate reductase gene contributes to hyperhomocysteinemia in patients taking anticonvulsants.
15551285 There is an association between the MTHFR polymorphisms and malignant lymphoma risk for all histological subtypes.
12039122 Carriage of the mutant allele of the MTHFR C677T polymorphism is associated with elevated serum levels of homocysteine and idiopathic recurrent miscarriage.
11927833 Polymorphisms in MTHFR is associated with the efficacy and toxicity of methotrexate used for the treatment of rhematoid arthritis
15916056 Finds no significant difference in the frequencies of MTHFR (C677T) gene polymorphism between the overweight/obese subjects and the control subjects
16274479 genetic influence of the methylenetetrahydrofolate reductase (MTHFR) 677C>T genotype on diabetic peripheral arterial disease is modest, yet for the Oji-Cree it is a major risk factor
16282888 Methylenetetrahydrofolate reductase polymorphisms are associated with pediatric stroke
16320685 Patients with homozygous MTHFR mutation less frequently developed recurrent ischemic stroke than patients without this mutation.
16514238 MTHFR gene mutation was evaluated in patients with severe pregnancy complications in northern Finland. The mutation was homozygous.
16538173 Variations in MTHFR function may contribute to individual differences in drug efficacy and toxicity, as well as disease risk.
16489479 MTHFR polymorphisms are risk factors for Down syndrome in Indian mothers.
16844951 The MTHFR C677T polymorphism was suggested to modify the risk for cervical artery dissection
16845248 MTHFR, eNOS, PAI-1 polymorphisms are susceptibility loci and genotypes of these genes are neither necessary nor sufficient for the coronary artery disease to occur, but coexistence of high-risk alleles may increase the severity of coronary artery disease
16861746 we showed the first genetic evidence that MTHFR C677T, MS A2756G and MTRR A66G genotypes were independently associated with male infertility. Each SNP of the three enzymes may have a different impact on the folate cycle during spermatogenesis
17208363 Neither the MTHFR nor the GCP gene polymorphisms showed an association to cancer diagnosis, to tumor stage, grade of differentiation or Lauren type.
17332146 association of homocysteine with cardiovascular disease was markedly attenuated after adjusting for risk factors and was not modified by MTHFR 677C>T or intake of folate or B-vitamins
17356914 according to this study, the MTHFR C677T mutation does not seem to be a risk factor for the progression of nonalcoholic fatty liver disease to nonalcoholic steatohepatitis
12027572 Genetic defent in homocysteine metabolism is a decreased activity of a common MTHFR variant, 677C-T, a thermolabile form.
16133896 Female with Takayasu arteritis, primary antiphospholipid antibody syndrome and methylene tetrahydrofolate reductase C 677 T and A 1298 C polymorphism, who was treated with carotid stenting and anticoagulants.
12534444 C677T MUTATION IS RELATED TO THE DEFECTS IN THE INTERNAL ELASTIC LAMINA OF THE ARTERY WALL
12673582 MTHFR gene C677T mutation associated with a predisposition to increase of plasma homocysteine may represent a genetic risk factor for diabetic retinopathy in Chinese type 2 diabetes mellitus.
14734201 significant interaction between serum folate and MTHFR genotype in predicting homocysteine concentrations
15126006 C677T mutation of MTHFR is common in the Chinese population; MTHFR C677T gene polymorphism associated with a predisposition to increased plasma homocysteine levels may represent a genetic risk factor for diabetic nephropathy in Chinese type 2 diabetics
15163465 C677T-MTHFR polymorphism is not an associated risk factor for developing preeclampsia in southeast Mexico
15385937 Polymorphismsof methylenetetrahydrofolate reductase are associated with chronic lymphocytic leukemia
15775757 MTHFR gene polymorphisms is associated with sudden hearing loss
15952099 Hyperhomocysteinemia, a risk factor for thrombosis, recurrent miscarriages, and osteoporosis, might derive from acquired folate and vitamin B 12 deficiencies and from a C677T mutation in methylene-tetrahydrofolate reductase (MTHFR) gene.
15750260 essential hypertension, like cardiovascular disease, may be mildly influenced by the MTHFR C677T variant.
11781870 frequent 5,10-methylenetetrahydrofolate reductase C677T polymorphism is associated with a common haplotype in whites, Japanese, and Africans
12594357 Homozygosity for the C677T mutation in the MTHFR gene does not constitute a genetic risk factor for coronary diseases and neural tube defects in the Indonesian Javanese population.
16172608 The elevated risk of schizophrenia associated with the homozygous genotype of the MTHFR 677C>T polymorphism provides support for causality between a disturbed homocysteine metabolism and risk of schizophrenia.
16310481 Wild-type MTHFR (methylenetetrahydrofolate reductase) in cataract may suggest impaired DNA synthesis as a cataractogenic factor.
11801474 The 677C-->T mutation of MTHFR was present in 26.1% of adults with idiopathic osteonecrosis of the femur head and appears to have a role in the complex pathophysiology of the disease.
15513477 Homozygosity for the 677C-T mutation in the MTHFR was found in four patients, in five controls in GROUP I and in four controls in GROUP II.
15961124 A bacterial model is developed for studying the effect of a common polymorphism in MTHFR in E coli.
16358830 Finds that the maternal folate and homocysteine levels along with the MTHFR 677 genetic polymorphism during pregnancy affect the DNA methylation in the human placenta
15009479 Polymorphism is not associated with myocardial infarct in Japan.
15510613 The common MTHFR C677T and TS enhancer region polymorphisms were not risk factors for breast cancer in this patient cohort nor were they associated with phenotypic features or with prognosis.
12133463 The risk of developing gastric cancer in the individuals with MTHFRC677T/C1298C was 17 times higher than that in the individuals with MTHFRC677C/A1298A.
12221667 Hyperhomocysteinemia and the homozygous C677T mutation in the MTHFR gene are important risk factors of Budd Chiari syndrome.
12522558 severity of CAD and is related to the MTHFR polymorphism, suggesting an interesting link between coronary atherosclerosis and genetic instability in humans.
12522678 Two CVT patients were identified C677T polymorphismof MTHFR gene.
15648053 MTHFR C677T mutation was significantly related to hyperhomocysteinemia
15958894 MTHFR C677T mutation has been identified as predisposing genetic factor for thrombosis.
16538645 results suggest that the distribution of the C677 T polymorphism may vary among lymphoproliferative diseases
16545905 This finding indicates possible association of BD and schizophrenia with the 1p36.3 MTHFR locus.
16549163 No correlation was determined between factor V Leiden, prothrombin G20210A, and Methylenetetrahydrofolate reductase C677T mutations and osteonecrosis in kidney allograft recipients.
16679643 Primary hyper-homocysteinemia appears to be an important risk factor for ischemic stroke in North Indians, most due to MTHFR C677T homozygosity.
16944145 MTHFR polymorphism C677T (TT) decreases the risk of Diffuse Large B-Cell Lymphoma, and the patients have much favorable response rates to chemotherapy.
17035405 Based on a meta-analysis, the common genetic C677T polymorphism in the MTHFR contributes to the risk of adult ALL, but not to the childhood ALL susceptibility.
17071478 the MTHFR A1298C polymorphism has a role in development of acute myeloid leukemia in Brazilian children
17047490 MTHFR 677T-1298A haplotype in genomic DNA has the potential to be a predictive marker of tumor response in rectal cancer patients submitted to preoperative chemoradiotherapy.
17206530 study demonstrates an association of the MTHFR C677T and SHMT(1) C1420T polymorphism with the risk of esophageal squamous cell carcinoma and gastric cardia adenocarcinoma
17275478 An effective risk factor was found when the polymorphisms of the MTHFR gene and hyperhomocysteinemia were associated with risk of chronic kidnen allograft dysfunction.
17353498 mildly elevated homocysteine levels as a result of MTHFR 677TT do not seem to cause venous thrombosis. There is no rationale for measuring the MTHFR 677C-->T variant for clinical purposes.
17436239 MTHFR 677C-->T polymorphism, folate, riboflavin, cobalamin, and vitamin B6 were independent predictors of plasma total homocysteine in multivariate models
17621533 In patients with pyruvate kinase deficiency and moya moya syndrome, a search for raised serum lipoprotein (a) concentrations and the C677T mutation of the methylenetetrahydrofolate reductase gene should be considered.
12042673 Polymorphism in Mthfr gene is associated with colorectal cancer risk
12590948 No association between the MTHFR A1298C and transcobalamin C776G genetic polymorphisms and hyperhomocysteinemia in thrombotic disease.
14585902 Variation in twinning frequency is not associated with MTHFR genotype.
14652356 MTHFR 677C-->T polymorphism negatively affects folate and homocysteine response in women consuming low folate diets followed by repletion with recommended dietary allowance
14763962 we have now investigated whether the different apolipoprotein E (APO E) genotypes, in pairwise combinations with the MTHFR 677TT or ACE D/D mutation, could lead to an increased risk of leukoaraiosis.
12187094 Hyperhomocysteinemia, serum folate levels and both C677T and A1298C MTHFR mutations are associated with cardiovascular disease in hemodialysis patients.
12187113 no association between the MTHFR reductase C677T polymorphism and the increased risk of the development of end-stage renal disease.
12826168 MTHFR C allele has a protective effect and MTHFR T allele has a detrimental effect on the serum lipid profile in kidney transplantation.
14499487 This study evidence of an allelic association between METHFR and schizophreia.the T667T, C1298C,C677T/C1298C and T677T/A1298A feneotypes were more frequently recorded among schizophrenic patients.
11940092 prevalence of the C677T mutation in the methylenetetrahydrofolate reductase gene
12576444 These findings support a role for MTHFR 677 TT genotype in reducing proximal CLC risk in North Italy.
12923861 polymorphisms in methylenetetrahydrofolate reductaseis associated with increased risk for Down syndrome
15494775 Methylenetetrahydrofolate reductase gene polymorphism is associated with endothelial dysfunction in healthy young men.
12775885 The MTHFR TT genotype is a risk factor for hypertension and carotid stenosis in Japanese women. Significant interactions with smoking were observed in women but not in men. Smoking cessation is important for prevention of cerebrovascular disease
12907815 The C677T polymorphism of the MTHFR gene was associated with increased risk of cerebral thrombotic stroke in a Chinese Multicenter Case-Control Study. Total plasma homocysteine was correlated with both ischemic and hemorrhagic stroke
15103709 No evidence for methylenetetrahydrofolate reductase enzyme polymorphisms as a maternal risk factor for Down syndrome.
15841723 MTHFR polymorphism is not associated with the development of adenocarcinoma of the upper gastrointestinal tract.
15935452 The gene-nutrient interaction that shows a higher risk for coronary artery disease (CAD) based on specific threshold folate levels required by different MTHFR C677T genotypes in a Korean population.
16046727 Plasma total homocysteine concentrations were highest in the subgroup of men with the polymorphisms, MTHFR 677C-->T TT, consistent with an increased risk of cardiovascular disease in men.
16123993 Genotyping of the MTHFR 677C polymorphism could have a prognostic value in the initial phase of treatment in Greek children.
16134079 data fail to support a relationship between MTHFR C677T and the risk for breast cancer; it may be that there are ethnic differences in terms of this relationship
16272757 detected a novel single nucleotide polymorphism (SNP) 148C>T (Arg46Trp) in exon 1 in Japanese individuals
16374229 We found that the MTHFR 677C-->T polymorphism is not likely to have a major role in the development of prostate cancer, although it may possibly increase the risk in combination with high plasma folate levels
16470725 MTHFR polymorphism is a significant risk factor for non-syndromic cleft lip and palate in Northern Chinese population.
16541270 Variant alleles did not play a key role in protection nor in increased risk for multiple myeloma: the effect of MTHFR on folate metabolism might be modified by diet intake
16683219 Doubly heterozygous prothrombotic genetic mutations are commonly present among Eastern Mediterranean patients with venous thromboembolism.
16923565 MTHFR polymorphisms may have a role in susceptibility to childhood acute lymphocytic leukemia
17005242 the MTHFR C677T polymorphism was not associated with an increased incidence of recurrent coronary event
17005529 MTHFR C677T genotype does not have a positive impact on survival in type 2 diabetes patients with end-stage diabetic nephropathy
17094971 Spontaneously aborted embryos have a unique distribution of MTHFR C677T and A1289C polymorphisms, regardless of their chromosomal integrity.
17454207 women with polycystic ovary syndrome (PCOS) have a higher incidence of risk factors for cardiovascular disease; the two PCOS groups studied have comparable frequencies of the methylenetetrahydrofolate reductase T (C677T) and C (A1298C) alleles
15608557 Study results suggest that MTHFR genotypes are relevant and independent factors of patient outcome in 5FU-based treatment of advanced colorectal neoplasms.
15385813 Thrombophilic gene mutations have only a moderate influence on hemostatic complications in patients undergoing stem cell transplantation.
12215845 TYMS and MTHFR compete for limiting supplies of folate required for the remethylation of homocysteine.
12784186 MTHFR 677 T/T genotype and T allele significantly associated with macroangiopathy in type 2 diabetes with renal failure. MTHFR 677 T allele and renal dysfunction due to diabetic nephropathy could be strong risk factors for atherosclerosis.
15068389 MTHFR C677T polymorphism displays a similar distribution pattern in lymphoid and myeloid leukemias and that the frequency of the homozygote variant genotype (677TT) is lower in all leukemia types.
15136061 A strong interaction is demonstrated between MTHFR genotype and smoking that greatly increases the homocysteine level in healthy adults
16177213 Genotypes conferring reduced MTHFR activity were associated with a decreased risk of acquired G:C-->A:T mutations within the p53 gene occurring at CpG sites
16402130 Evidence was found of an increased risk of ever being diagnosed as depressed in MTHFR C677T TT individuals compared with CC individuals. Findings suggest that folate or its derivatives may be causally related to risk of depression.
11870335 polymorphism and ischemic stroke: sex difference in Japanese. 51.47, P=0.0091). T/T mutation appears to be restricted to women.
15114595 The prevalence of homozygous gene mutation for MTHFR was higher among patients with stroke than control subjects
15834927 a genetic background such as the MTHFR C677T polymorphism responsible for hyperhomocysteinemia plays a role in the development of higher degree of steatosis, which in turn accelerates the progression of liver fibrosis in chronic hepatitis C
16015408 Single nucleotide polymophism in thrombophilia.
16015422 MTHFR C677T polymorphism does not represent a useful marker of increased risk for repeated pregancy loss.
16207540 Results did not show sufficient evidence for an association between MTHFR C677T genotype and congenital heart disease.
12949355 In vitro activity of the T/T MTHFR enzyme was approximately half that of the C/C genotype. 5-Methyltetrahydrofolate in cells with T/T genotype was approximately half that of cells with wild-type MTHFR.
15301885 A common point mutation (C677T) in the gene for 5,10-methylenetetrahydrofolate reductase (MTHFR) is significantly associated with major adverse cardiac events after myocardial revascularization in CAD patients
12180076 Mutants may be associated with neural tube defects, but associated is too weak to recommend using MTHFR for screening.
12797455 We suggest that the association between the infant MTHFR homozygous variant genotype and spina bifida risk may be conditional upon both lesion level and maternal vitamin use.
12797595 An increased hypertensive risk was observed in those MTHFR TT males with tHcy levels higher than 15 micromol/L (OR = 2.78; 95% CI = 1.05-7.3; P = 0.032) but not in those non-TT males with tHcy levels higher than 15 micromol/L (P = 0.33).
12844196 Thereis no evidence that MTHFR polymorphism is a risk factor for myocardial infarction in a young South African Indian based population.
14608052 Age and sex modify the contribution of the MTHFR C677T mutation to fasting plasma homocysteine concentrations.
14608109 MTHFR 677C-->T polymorphism affects cancer risk (review)
15007309 C677I mutation is linked to anterior ischemic optic neuropathy.
14698652 The methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms and thrombotic disease in North Western Russia.
15311088 the meta-analysis suggests that the T allele may increase the risk of severe diastolic hypertension during pregnancy.
15564899 A minor role for polymorphism of this enzyme in the pathogenesis of schizophrenia and depression cannnot be ruled out and would warrant further investigation.
15970629 C677T and A1298C MTHFR polymorphisms should be examined when assessing genetic risk factors of hyperhomocysteinemia in epilepsy.
15004488 Polymorphisms in the MTHFR gene are associated with breast cancer in premenopausal women.
15298954 The MTHFR gene polymorphism maybe associated with reduced risk of progression of prostate cancer.
15735067 In children and adults, plasmaconcentration is important in determining the contribution of the MTHFR C677T mutation to homocysteine concentrations in children.
15735068 MTHFR) 677C-->T polymorphism is thought to influence the partitioning of 1-carbon units between methylation and other components of 1-carbon metabolism.
15811073 results show a significantly increased frequency of C677T heterozygotes among infertile patients (p value <0.04). More importantly, while there were no T homozygotes in the control population, six of 151 infertile cases were T homozygous.
15820491 The effect of C677T methylenetetrahydrofolate reductase and A2756G methionine synthase polymorphisms could affect the relative risk for MI is reported.
15867278 Plasma total homocysteine concentrations in subjects with the MTHFR 677 T/T genotype were inversely related to 5-methyl folate concentrations and directly related to formylated folate concentrations in erythrocytes.
15867279 Elevated homocysteine synthesis is a cause of mild hyperhomocysteinemia in women with marginal folate status, particularly those with the MTHFR 677 T/T genotype.
15868433 MTHFR C677T polymorphisms may affect long-term survival from advanced breast cancer
16097444 Homozygosity for the low-activity C677T genotype (TT) of MTHFR may represent a genetic determinant increasing breast cancer risk
16624841 results support the assumption of a causal relationship among the MTHFR genotype, tHcy and stroke.
16704755 Polymorphism of the MTHFR gene is associated with hyperhomocysteinaemia, lipid dysregulation and the presence of coronary artery disease
16774768 MTHFR C677T genotype is a significant factor for hyperhomocysteinemia in patients with PD, levodopa-untreated and probably even more in levodopa-treated PD patients.
16808252 The polymorphic C677T and A1298C variants of the MTHFR gene are associated with an increase in the level of homocysteine, which is risk factor of pregnancy loss.
16894458 analysis