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MUC1
| Symbol: | MUC1 | | Name(s): | mucin 1, cell surface associated | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CD227, EMA, H23AG, MAM6, PEM, PEMT, PUM | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18161663 |
CA 15-3 levels might have a role in the response to EGFR inhibitors in patients with bronchioloalveolar carcinoma |
| 18268124 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17916995 |
A high correlation between MUC1 and cyclin D1 implies MUC1 involvement in the Wnt cascade functioning in a large subset of human papillary thyroid carcinoma and papillary microcarcinoma |
| 18037881 |
MUC1 is important for physiological activation of IKKbeta and that overexpression of MUC1, as found in human cancers, confers sustained induction of the IKKbeta-NF-kappaB p65 pathway. |
| 11062147 |
Observational study of gene-disease association. (HuGE Navigator) |
| 11464247 |
Observational study of gene-disease association. (HuGE Navigator) |
| 12105832 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 12734543 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15944787 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16357367 |
Observational study of gene-disease association and genetic testing. (HuGE Navigator) | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| BIND | Human bax gene, 5' region. | mucin 1, transmembrane | MUC1 C-ter interacts with the Bax promoter. | - | Pubmed |
| BIND | Human p21 gene, partial promoter sequence. | mucin 1, transmembrane | MUC1 C-ter interacts with the p21 promoter. | - | Pubmed |
| BIND | catenin, beta 1, 88kDa | mucin 1, transmembrane | MUC1 interacts with beta-catenin. | - | Pubmed |
| HPRD | catenin, beta 1, 88kDa | Mucin-1 precursor (Breast carcinoma... | - | - | Pubmed |
| HPRD | catenin, beta 1, 88kDa | Mucin-1 precursor (Breast carcinoma... | - | - | Pubmed |
| HPRD | catenin, delta 1 isoform 1B | Mucin-1 precursor (Breast carcinoma... | - | - | Pubmed |
| HPRD | epidermal growth factor receptor oncogene homolog, avian) | Mucin-1 precursor (Breast carcinoma... | - | - | Pubmed |
| HPRD | epidermal growth factor receptor oncogene homolog, avian) | Mucin-1 precursor (Breast carcinoma... | - | - | Pubmed |
| BIND | epidermal growth factor receptor isoform a | mucin 1, transmembrane | MUC1 interacts with and is tyrosine-phosphorylated by EGFR. | - | Pubmed |
| HPRD | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog | Mucin-1 precursor (Breast carcinoma... | - | - | Pubmed |
Recent Publications on MUC1: |  |
Surface Mucin-1 does not play a role in dendritic cell migration.
Mucin-1 (MUC1) is a transmembrane glycoprotein that is upregulated upon... | 28th October, 2008
| Department of Internal Medicine, Division of Haematology, University
| Mol Immunol. 2008 Oct 24.
DOI Direct Link |
Positive KL-6 mucin expression combined with decreased membranous beta-catenin expression indicates worse prognosis in colorectal carcinoma.
Interaction of MUC1 with beta-catenin plays a significant role in tumor... | 25th October, 2008
| Minimally Invasive Surgery Center, Changzheng Hospital, Second Military
| Oncol Rep. 2008 Nov;20(5):1013-9.
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Adenovirus-mediated gene transfer of pathogen-associated molecular patterns for cancer immunotherapy.
The delivery of stimulatory signals to dendritic cells (DCs) in the tumor... | 25th October, 2008
| 1Molecular Immunology Department, Transgene, Strasbourg, France.
| Cancer Gene Ther. 2008 Oct 24.
DOI Direct Link |
MUC1 expression in canine malignant mammary tumours and relationship to clinicopathological features.
Mucin-1 (MUC1) is over-expressed in human breast carcinomas and is linked... | 25th October, 2008
| Institute of Molecular Pathology and Immunology (IPATIMUP), Rua Dr.
| Vet J. 2008 Oct 21.
DOI Direct Link |
MVA-MUC1-IL2 vaccine immunotherapy (TG4010) improves PSA doubling time in patients with prostate cancer with biochemical failure.
Purpose: TG4010 is a recombinant MVA vector expressing the... | 22nd October, 2008
| Department of Solid Tumor Oncology Taussig Cancer Center, Cleveland
| Invest New Drugs. 2008 Oct 18.
DOI Direct Link |
→View more research publications. |
MUC1 results (if any) from reagent suppliers | 
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MUC1 antibodies | Abcam
MUC1 antibodies. ... MUC1 antibody [LBS-1]. ICC/IF, IHC-Fr. Mouse monoclonal ... MUC1 antibody [PR 4D1]. IHC-FoFr. Mouse monoclonal ...
http://www.abcam.com/index.html?t=53037&pt=1&c=751...
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Muc1.
29 Apr 2003 ... Muc1 is a heavily O-glycosylated transmembrane protein ... cancer Muc1 is overexpressed; is underglycosylated and the ...
http://www.exalpha.com/pdfs/X1602M.pdf...
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MUC1 antibody [M9E7] (ab8322) datasheet | Abcam
Mouse monoclonal [M9E7] to MUC1. MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some ...
http://www.abcam.com/MUC1-antibody-M9E7-ab8322.html...
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GTX28323-MUC1 antibody [M2C5]-GeneTex Inc.
MUC1 antibody [M2C5] 4M40-M2C5 GTX28323 GTX28323 Mouse monoclonal [M2C5] to MUC1 CA 15-3 CA15-3 MAM6 M2C5 4582 | MUC1 | 158340 | P15941 | CD227 | EMA ...
http://www.genetex.com/commerce/catalog/product.jsp?product_...
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MUC1 antibody, MUC1 [X19] antibody Antibody, Mouse IgG Monoclonal ...
Buy quality mouse MUC1 antibody (interacts with human), anti-MUC1, MUC1 [X19] antibody antibody, ... Mouse monoclonal [X19] to MUC1, N/A. [ N/AN/AN/A ].
http://www.genwaybio.com/product_info.php?products_id=190085...
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GTX10118-MUC1 antibody [M2F1]-GeneTex Inc.
MUC1 antibody [M2F1] 4M40-M2F1 GTX10118 10118 GTX10118 M2F1 MUC1 MUC1 M2F1 M2F1 MUC1 ab10118 M2F1 MUC1 MUC1 M2F1 M2F1 MUC1 Breast carcinoma associated ...
http://www.genetex.com/commerce/catalog/product.jsp?product_...
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Eurogentec - Research - MUC-1 Monoclonal Antibody, Purified (SIGNET)
Purified Monoclonal Antibody against MUC-1 (BC2), (Formerly Signet Catalog No: 621-01)
http://www.eurogentec.com/product/research-muc-1-monoclonal-...
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GTX10119-MUC1 antibody [M3A106]-GeneTex Inc.
MUC1 antibody [M3A106] 4M40-M3A106 GTX10119 10119 GTX10119 M3A106 MUC1 MUC1 M3A106 M3A106 MUC1 M3A106 MUC1 MUC1 M3A106 M3A106 MUC1 Breast carcinoma ...
http://www.genetex.com/commerce/catalog/product.jsp?product_...
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Muc1 antibody, Muc1 Antibody, Mouse IgG Monoclonal Antibody
Buy quality mouse Muc1 antibody (interacts with n/a), anti-Muc1, Muc1 antibody, mouse igg monoclonal antibody, Muc1 Antibody, Mouse IgG Monoclonal Antibody ...
https://www.genwaybio.com/product_info.php?products_id=24010...
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MUC1 antibody, Mucin-1 Antibody, Chicken IgY Polyclonal Antibody
Buy quality chicken MUC1 antibody (interacts with human mouse rat), anti-MUC1, Mucin-1 antibody, chicken igy polyclonal antibody, Mucin-1 Antibody, ...
http://www.genwaybio.com/product_info.php?products_id=600...
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