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Abl
| Symbol: | Abl | | Name(s): | Abl tyrosine kinase | | Type: | protein-coding | | Organism: | Drosophila melanogaster | | Synonyms: | 4674, Abl1, AblK, Ableson, Am ABL, C-abl, CG4032, D-abl, D-ash, DAbl, DROTKABL3, Dash, Ddash/abl, Dsrc7, cAbl, l(3)04674, l(3)73Ba, l(3)c-abl | | Links: |
Pubmed,
Entrez Gene,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17804420 |
These findings suggest that the reciprocal regulation of Abi phosphorylation by Abl and PTP61F may regulate the localization and stability of Abi and may regulate the formation of lamella. |
| 12783792 |
amalgam, neurotactin and the Abelson tyrosine kinase interact and affect axon pathfinding |
| 17202187 |
Abl acts apically to suppress the accumulation of both Enabled (Ena) and actin in mesodermal cells during ventral furrow formation |
| 15975902 |
a reduction in Abl gene dosage causes distal paralysis and axonal swellings |
| 14676307 |
In Abl's absence, excess actin is polymerized in apical microvilli, whereas too little actin is assembled into pseudocleavage and cellularization furrows. |
| 16003769 |
Enabled (Ena), a substrate for Abl, promotes the formation of both dendritic branches and actin-rich spine-like protrusions of dendritic arborization neurons, an effect opposite to that of Abl |
| 16932754 |
Therefore, we propose that Abl and p35/p25 cooperate in promoting Cdk5-pY15, which deregulates Cdk5 activity and subcellular localization in Abeta42-triggered neurodegeneration. |
| 11864995 |
Mutated c-Abl stimulated the formation of F-actin branches in neurites of rat embryonic cortical neurons. The reciprocal regulation between F-actin and the c-Abl tyrosine kinase may provide a mechanism for control of actin cytoskeleton dynamics |
Press Releases on Abl:
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| MultiVu Video Feed: BASKETBALL LEGEND KAREEM ABDUL-JABBAR ANNOUNCES HE HAS BEEN DIAGNOSED WITH CHRONIC MYELOID LEUKEMIA; AIMS TO INSPIRE OTHERS |
10th November, 2009 |
Novartis |
Kareem Abdul-Jabbar, one of the greatest basketball players of all time,
known for his unblockable signature "sky hook" shot, has announced that he
was diagnosed late last year with a
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| Data Shows Longest Ever Survival for Patients With Life-Threatening Leukaemia Treated With Breakthrough Treatment |
8th December, 2008 |
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FRIMLEY, England, December 8 /PRNewswire/ -- Nearly nine out of ten patients (86 percent) with a
life-threatening leukaemia are still alive seven years after diagnosis when
treated with Glivec
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| Emerging oncology treatments: A focus on targeted therapeutics,
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1st June, 2006 |
Dailyupdates |
Emerging oncology treatments: A
focus on targeted therapeutics, supergeneric reformulations and
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| Peakdale launches 5th Class A GPCR library and announces plans to develop
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1st January, 1970 |
Peakdale |
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| Peakdale and BioLeap collaborate on drug-like kinase library |
1st January, 1970 |
Peakdale |
Peakdale and
BioLeap collaborate on drug-like kinase library
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Abl results (if any) from reagent suppliers | 
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