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nec
| Symbol: | nec | | Name(s): | necrotic | | Type: | protein-coding | | Organism: | Drosophila melanogaster | | Synonyms: | CG1857, SER3, Spn43Ac, anon-WO0118057.3 | | Links: |
Pubmed,
Entrez Gene,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 16835244 |
Data demonstrate a critical role for basic residues within the D-helix (and lysine 68 in particular) in the inhibitory mechanism of the serpin Necrotic. |
| 16360948 |
finding indicates that cleavage of the Necrotic amino-terminal extension might modulate Toll activation following the initial immune response |
| 12414799 |
likely to inhibit a wide range of proteases in Drosophila and has the specificity requirements to act as the physiological inhibitor of Persephone in vivo |
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