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MYH9
| Symbol: | MYH9 | | Name(s): | myosin, heavy chain 9, non-muscle | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | DFNA17, EPSTS, FTNS, MGC104539, MHA, NMHC-II-A, NMMHCA | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18059020 |
subjects with mutations in the motor domain present with severe thrombocytopenia and develop nephritis and deafness before the age of 40, while those with mutations in the tail domain have a much lower risk of complications and higher platelet counts |
| 17901043 |
An MYH9 human disease model in flies. |
| 15477207 |
Observational study of genetic testing. (HuGE Navigator) |
| 18195072 |
during T lymphocyte migration, uropodal adhesion depends on LFA-1 avidity, where MyH9 serves as a key mechanical link between LFA-1 and the cytoskeleton that is critical for LFA-1 de-adhesion |
| 17645784 |
MyosinIIa contractility is required for maintenance of platelet structure during spreading on collagen and contributes to thrombus stability |
| 17327270 |
MIIA plays a role in CXCR4 endocytosis, which involves its dynamic association with beta-arrestin and highlights the role of endogenous MIIA as a regulator of CXCR4 internalization and, therefore, the onset of SDF-1alpha signaling. |
| 17875677 |
myosin IIA is required for a critical step between NK immunological synapse formation and granule exocytosis |
| 17567956 |
These observations support a direct role for myosin-IIA heavy-chain phosphorylation in mediating motility and chemotaxis. |
| 17488351 |
direct platelet myosin IIA participation in internal contraction |
| 15865432 |
Casein kinase 2 phosphorylation of the myosin-IIA heavy chain protects against Ca2+-regulated S100 family member MTS1-induced filament disassembly and inhibition of assembly of nonmuscle myosin-IIA filaments. | →View more information from publications. |
Recent Publications on MYH9: |  |
New insights into the role of podocytes in proteinuria.
Disturbances in many different molecular pathways and interactions can... | 30th October, 2009
| Department of Renal Medicine, Karolinska University Hospital, Stockholm,
| Nat Rev Nephrol. 2009 Aug;5(8):463-8. Epub 2009 Jul 7.
DOI Direct Link |
MYH9 related disease: A novel missense Ala95Asp mutation of the MYH9 gene.
MYH9-related disease (MYH9-RD) is a rare autosomal dominant disorder... | 29th October, 2009
| Medical Genetics, Department of Reproductive and Developmental Sciences,
| Platelets. 2009 Oct 27.
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Clinical manifestation and molecular genetic characterization of MYH9 disorders.
Currently, the May-Hegglin anomaly (MHA), Sebastian (SBS), Fechtner (FTNS)... | 29th October, 2009
| Institute of Haematology and Blood Transfusion, Prague, Czech Republic.
| Platelets. 2009 Aug;20(5):289-96.
DOI Direct Link |
Susceptibility genes in common complex kidney disease.
PURPOSE OF REVIEW: This paper reviews recent efforts to identify genetic... | 20th October, 2009
| aDivision of Public Health Sciences, USA bDepartment of Internal Medicine
| Curr Opin Nephrol Hypertens. 2009 Oct 15.
DOI Direct Link |
CKD in MYH9-related disorders.
MYH9-related disorders are rare causes of chronic kidney disease (CKD)... | 3rd October, 2009
| Department of Internal Medicine, Section of Nephrology, The Ohio State
| Am J Kidney Dis. 2009 Oct;54(4):732-40. Epub 2009 Sep 2.
DOI Direct Link |
→View more research publications. |
MYH9 results (if any) from reagent suppliers | 
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MYH9/10 (3H2) Antibody sc-33729
MYH9/10 (3H2): sc-33729 antibody 및 MYH9/10 (3H2) antibody conjugates를 사용한 논문들을 보세요. Wang, C. et al. 2008. Kruppel-like factor 4 is required for ...
http://www.scbt.com/ko/datasheet-33729-MYH9-10-3h2-antibody....
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M8064 Anti-Myosin IIA, non muscle antibody produced in rabbit ...
microarray: suitable. Gene Information, human ... MYH9(4627). rat ... Myh9(25745 ). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=M806...
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Myosin Antibody / Myosin Antibodies
MYH9 (G-12) Antibody, sc-47200, goat IgG, Internal (h), WB, IF, ELISA, m, r, h. MYH9 (H-40) Antibody, sc-98978, rabbit IgG, 1741-1780 (h), WB, IP, IF, ELISA ...
http://www.scbt.com/table-myosin.html...
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Myosin II Isoform Antibody Sampler Kit #5144
The heavy chains (NMHCs) are encoded by three genes, MYH9, MYH10 and MYH14, which generate three different nonmuscle myosin II isoforms, IIa, IIb and IIc,
...
http://www.cellsignal.com/products/5144.html...
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MYH9 siRNA (m) sc-61121
Click here for details. suitable control antibody: MYH2 (A4.74): sc-53095; sqRT- PCR Primer also available: MYH9 (m)-PR: sc-61121-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-61121-MYH9-sirna-m.html...
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Myosin IIa Antibody
MYH9, MYH10 and MYH14, which generate three different nonmuscle myosin II isoforms, IIa, IIb and IIc, respectively. (reviewed in 1). ...
http://www.cellsignal.com/pdf/3403.pdf...
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MYH9 (D-16) Antibody sc-47199
MYH9 (D-16) 抗体 sc-47199 MYH9 (D-16) Antibody sc-47199.
http://www.scbt.com/ja/datasheet-47199-MYH9-d-16-antibody.ht...
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