Sunday November 22 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

ATF1


Suggest Content
Advertise Here
Gene DB Home
Symbol:ATF1
Name(s):activating transcription factor 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:EWS-ATF1, FUS/ATF-1, TREB36
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17565989 PIAS3 is a new regulator of ATF1 that regulates the ARE-mediated transcription of the ferritin H gene
15884099 Simultaneous expression of the EWSR1-ATF1 and MITF-M transcripts in clear cell carcinoma has led to the proposal that the MITF-M promoter is transactivated by EWSR1-ATF1.
12748173 transcriptional activation of the interleukin-8 promoter by bradykinin involves the prostanoid-independent activation of nuclear factor-kappaB, and prostanoid-dependent activation of activating protein-1 and nuclear factor-interleukin-6
14767471 The role of activator protein-1 in regulating the promoter of IFGBP4 was studied in CaCo-2 cells.
16227528 CREB/ATF1 and c-Jun were shown to bind to an oligonucleotide encompassing a distal, conserved CREB/AP1 site in the 5'-flanking region of the MUC2 gene, and this cis element was shown to mediate promoter reporter activation by VIP
16327442 There was evidence of ATF1 oncogene protein fusion in this sarcoma.
12391222 ATF1 plays an important role in the trans-activation of the MHC class II trans-activator (CIITA) promoter III in B cells.
11877423 Composition and function of AP-1 transcription complexes during muscle cell differentiation
12631284 Results demonstrate that c-Src and TRAF6 are key mediators of interleukin-1-induced AP-1 activation and provide evidence of cross talk between c-Src and TRAF6 molecules through PI3 kinase-Akt-JNK pathways.
12195699 APC inhibited both the binding of NF-kB to target sites and the degradation of I kappa B alpha, and inhibited both the binding of activator protein-1 (AP-1) to target sites and the activation of mitogen-activated protein kinase pathways.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDActivating transcription factor 1GA binding protein transcription factor, alpha subunit--Pubmed
HPRDActivating transcription factor 1jun oncogene--Pubmed
HPRDActivating transcription factor 1spleen focus forming virus proviral integration oncogene spi1--Pubmed
HPRDActivating transcription factor 1CREB binding protein--Pubmed
HPRDActivating transcription factor 1GA binding protein transcription factor, beta subunit 2 isoform beta 1--Pubmed
HPRDActivating transcription factor 1cAMP responsive element binding protein 1 isoform B--Pubmed
HPRDactivating transcription factor 1Active transcription factor CREB--Pubmed
HPRDactivating transcription factor 1SPI1--Pubmed
HPRDactivating transcription factor 1c Jun--Pubmed
HPRDactivating transcription factor 1CREBBP--Pubmed

Recent Publications on ATF1:

Pubmed Logo
Stress-Induced Phosphorylation of S. pombe Atf1 Abrogates Its Interaction with F Box Protein Fbh1.
The Atf1 transcription factor is critical for directing stress-induced...
20th October, 2009
Cell Regulation Group, Paterson Institute for Cancer Research, University Curr Biol. 2009 Oct 14.
DOI Direct Link
Heterogeneous nuclear ribonucleoprotein R enhances transcription from the naturally configured c-fos promoter in vitro.
Transcription of a proto-oncogene c-fos is induced rapidly to high levels...
20th October, 2009
Department of Biochemistry, Graduate School of Comprehensive Human J Biol Chem. 2009 Aug 28;284(35):23472-80. Epub 2009 Jul 6.
DOI Direct Link
Utility of FISH in the diagnosis of angiomatoid fibrous histiocytoma: a series of 18 cases.
Angiomatoid fibrous histiocytoma is a mesenchymal neoplasm of intermediate...
6th October, 2009
Department of Anatomic Pathology, Pathology and Laboratory Medicine Mod Pathol. 2009 Oct 2.
DOI Direct Link
The transcription factor Atf1 binds and activates the APC/C ubiquitin ligase in fission yeast.
Fission yeast Atf1 is a member of the ATF/CREB basic leucine zipper (bZIP)...
6th October, 2009
Cell Cycle Control Laboratory, Marie Curie Research Institute, The Chart, J Biol Chem. 2009 Sep 4;284(36):23989-94. Epub 2009 Jul 7.
DOI Direct Link
Clear cell sarcoma of soft tissue metastatic to the ovaries: a heretofore unreported occurrence.
Clear cell sarcoma of soft tissue (CCSST) is a rare soft tissue neoplasm...
2nd October, 2009
Department of Pathology, University of Maryland Medical Center, Baltimore, Int J Gynecol Pathol. 2009 May;28(3):234-8.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
6194632 Mouse model for congestive heart failure
6706867 DNA array sequence selection
6793926 Methods for production of a recombinant adeno-associated virus
6821512 Compositions and methods for increasing packaging and yield of recombinant adenoviruses using multiple packaging signals
6821751 Hypoxia responsive transcription enhancer element from yeast

View more patents.

ATF1 results (if any) from reagent suppliers

Google CSE Logo
ATF-1 (25C10G) Antibody sc-270
See how others have used ATF-1 (25C10G): sc-270 antibody and or ATF-1 ... Western blot analysis of ATF-1/CREB gene family product expression in KNRK
nuclear ...
http://www.scbt.com/datasheet-270-atf-1-25c10g-antibody.html...

Thumbshot
ATF1 antibody (ab52845) | Abcam
ATF1 (Activating Transcription Factor 1, TREB-36) is a member of the ATF/CREB family of basic region leucine-zipper (bZip) DNA-binding proteins that r...
http://www.abcam.com/ATF1-antibody-ab52845.html...

Thumbshot
ATF-1 (C41-5.1) Antibody sc-243
See how others have used ATF-1 (C41-5.1): sc-243 antibody and or ATF-1 ... Western blot analysis of ATF-1 p35 expression in A-431 cells at antibody ...
http://www.scbt.com/datasheet-243-atf-1-c41-5-1-antibody.htm...

Thumbshot
ATF1 - S.pombe antibody [ATF1 2A9/8] (ab18123) | Abcam
Mouse monoclonal [ATF1 2A9/8] to ATF1 - S.pombe. ATF1 in S. pombe is a bZIP transcription factor with strong homology to the mammalian factor ATF1....
http://www.abcam.com/ATF1-S-pombe-antibody-ATF1-2A9-8-ab1812...

Thumbshot
ATF-1 (FI-1) Antibody sc-241
ATF-1 shRNA (h) Lentiviral Particles, sc-29754-V, 200 µl ... See how others have used ATF-1 (FI-1): sc-241 antibody and or ATF-1 (FI-1) antibody conjugates. ...
http://www.scbt.com/datasheet-241-atf-1-fi-1-antibody.html...

Thumbshot
Anti-ATF1 - DISCONTINUED Polyclonal Antibody
Polyclonal Antibody against ATF1 - DISCONTINUED for use in Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

Thumbshot
ATF-1 (ATF1 2A9/8) Antibody sc-53172
mouse monoclonal IgG2a, 200µg/ml; raised against ATF1 of S.pombe origin ... ATF- 1 (ATF1 2A9/8): sc-53172. Western blot analysis of ATF-1 expression in ...
http://www.scbt.com/datasheet-53172-atf-1-atf1-2a9-8-antibod...

Thumbshot

Search Bioportfolio and other Life Science Sites for ATF1, or search for ATF1 on BioPortfolio's antibody search engine.
This page has been viewed 558 times
Recent Search Terms used to find this page:
Activating transcription factor 1 ATF1 | activating transcription factor | ATF1 nfkb | atf1 transcription factor | EWSR1-ATF1 mitf | atf antibody | c-Jun activating transcriptions factor 1 | Atf-1 transcription factor | ATF1 and JNK | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.