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CEACAM6
| Symbol: | CEACAM6 | | Name(s): | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CD66c, CEAL, NCA | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18223215 |
data support an important role for CEACAM6 in endocrine resistance in breast cancer, which can serve as a powerful predictor of future recurrence |
| 17960155 |
Observational study of gene-disease association. (HuGE Navigator) |
| 16899629 |
The expression of CEACAM6 in ADH lesions is strongly associated with the development of IBC, therefore, it can be applied as a diagnostic marker either singly or in combination with other marker(s) to predict IBC development in women with ADH lesions. |
| 17503391 |
CEACAM6 is a biological tumor marker for epithelial ovarian cancers. |
| 15130118 |
the results show that recognition of CEA and CEACAM6, but not CEACAM1, is accompanied by tight attachment to bacteria of cell surface microvilli-like extensions |
| 17201906 |
For all tumors, the amount of CEACAM6 expressed was greater than that of CEACAM5, and reflected tumor histotype. |
| 12571231 |
CEACAM6 subdomains involved in intercellular adhesion activity and subdomains involved in inhibition of cell differentation are identified and their respective activities are independently blocked. |
| 15081416 |
overexpression among human malignancies, immunological targeting of this tumor antigen may have therapeutic applicability |
| 15316565 |
Levels of CEACAM6 expression can modulate pancreatic adenocarcinoma cellular invasiveness in a c-Src-dependent manner |
| 16115956 |
Data show that variants of Neisseria gonorrhoeae that bind to human carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) 1 and 6 failed to induce detachment and, instead, promoted enhanced host cell adhesion to the ECM. | →View more information from publications. |
Recent Publications on CEACAM6: |  |
Differentiation of a highly tumorigenic basal cell compartment in urothelial carcinoma.
Highly tumorigenic cancer cell (HTC) populations have been identified for... | 31st October, 2009
| Department of Pathology, The Johns Hopkins Medical Institutions,
| Stem Cells. 2009 Jul;27(7):1487-95.
DOI Direct Link |
Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM.
Abnormal expression of CEACAM6 is observed at the apical surface of the... | 23rd October, 2009
| Universite Clermont 1, Pathogenie Bacterienne Intestinale, JE2526, Unite
| J Exp Med. 2009 Sep 28;206(10):2179-89. Epub 2009 Sep 8.
DOI Direct Link |
PDEF and PDEF-induced proteins as candidate tumor antigens for T cell and antibody-mediated immunotherapy of breast cancer.
Novel breast tumor antigens are needed to develop T cell and... | 19th September, 2009
| Department of Immunology, Roswell Park Cancer Institute, Elm and Carlton
| Immunol Res. 2009 Sep 10.
DOI Direct Link |
Aggressive inherited and sporadic medullary thyroid carcinomas display similar oncogenic pathways.
RET oncogene mutations are found in familial medullary thyroid carcinomas... | 14th August, 2009
| N Ameur, Gustave Roussy, Villejuif, France.
| Endocr Relat Cancer. 2009 Aug 12.
DOI Direct Link |
Preclinical evaluation of carcinoembryonic cell adhesion molecule (CEACAM) 6 as potential therapy target for pancreatic adenocarcinoma.
Despite the availability of new targeted therapies, ductal pancreatic... | 1st August, 2009
| Department of Pathology, Genentech Inc., South San Francisco, CA, USA.
| J Pathol. 2009 Jul;218(3):380-90.
DOI Direct Link |
→View more research publications. |
CEACAM6 results (if any) from reagent suppliers | 
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CEACAM6 antibody (ab56234) | Abcam
The normal crossreacting antigen (NCA) or CEACAM6 belongs to the carcinoembryonic antigen (CEA) gene family. CEACAM6 is a GPI anchored membrane
protei...
http://www.abcam.com/CEACAM6-antibody-ab56234.html...
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Monoclonal Anti-human CEACAM-6-Allophycocyanin
CEACAM-6: Supplied as 10 μg of antibody in 1 mL saline containing up ... bearing CEACAM-6 within a population and qualitatively ...
http://www.rndsystems.com/pdf/FAB3934A.pdf...
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CEACAM6 antibody [9A6], prediluted (ab59113) | Abcam
Mouse monoclonal [9A6] to CEACAM6, prediluted. The normal crossreacting antigen (NCA) or CEACAM6 belongs to the carcinoembryonic antigen (CEA) gene family.
http://www.abcam.com/CEACAM6-antibody-9A6-prediluted-ab59113...
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CEACAM-6/CD66c - R&D Systems
CEACAM-6, previously called nonspecific crossreacting antigen (NCA) or CD66c, is a highly glycosylated 90 kDa, 286 aa, GPI-linked membrane protein of the ...
http://www.rndsystems.com/molecule_detail.aspx?m=3423...
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Molecular Biology, CEACAM 6, Recombinant, Human
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM-6), previously called nonspecific crossreacting antigen (NCA) or CD66c, is one of seven ...
http://www.usbio.net/displayPage.php?ProdSku=C2589-79C...
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Recombinant Human CEACAM6/CD66c
CEACAM6 is an intercellular adhesion molecule, ... When 2 x 105 cells/well are added to CEACAM6 coated plates (10 µg/mL,. 100 µL/well), 35 60% of the cells ...
http://www.rndsystems.com/pdf/3934-CM.pdf...
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CEACAM 5 + 6 antibody [MUS] - Azide free (ab4539) | Abcam
MUS reacts specifically with CEACAM 5 (CEA/CD66e) and CEACAM 6 (NCA/CD66c) ... CEACAM 6 expression is strongly up-regulated already during early stages of ...
http://www.abcam.com/ceacam-5-6-antibody-mus-azide-free-ab45...
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