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NCBP1


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Symbol:NCBP1
Name(s):nuclear cap binding protein subunit 1, 80kDa
Type:protein-coding
Organism:Homo sapiens
Synonyms:CBP80, MGC2087, NCBP
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17499042 We show that NELF interacts with the nuclear cap binding complex (CBC), a heterodimeric, multifunctional factor that plays important roles in several mRNA processing steps, and the two factors together participate in the 3' end processing of histone mRNAs
12374755 crystal structure at 2.1 A resolution of CBP20 and CBP80 bound to an m(7)GpppG cap analogue
16317009 Association of CBC with PARN might have importance in the regulated recruitment of PARN to the nonsense-mediated decay pathway during the pioneer round of translation.
12434151 Structural basis of m7GpppG binding to the nuclear cap-binding protein complex.
16186820 During nonsense-mediated mRNA decay, CBP80 interacts with Upf1 and promotes the interaction of Upf1 with Upf2 but not with Stau1.
16156639 The organization of the CBP80-CBP20 complex suggests how the activity of eIF4G in translation initiation could be regulated through a dynamic network of overlapping intra- and intermolecular interactions.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDBCL2/adenovirus E1B 19kD interacting protein 1 isoform BNIP1-cnuclear cap binding protein subunit 1, 80kDa--Pubmed
HPRDBCL2/adenovirus E1B 19kD interacting protein 1 isoform BNIP1-cnuclear cap binding protein subunit 1, 80kDa--Pubmed
HPRDBCL2/adenovirus E1B 19kD-interacting protein 3nuclear cap binding protein subunit 1, 80kDa--Pubmed
HPRDBCL2/adenovirus E1B 19kD-interacting protein 3nuclear cap binding protein subunit 1, 80kDa--Pubmed
HPRDeukaryotic translation initiation factor 4 gamma, 1 isoform 1nuclear cap binding protein subunit 1, 80kDa--Pubmed
BINDeukaryotic translation initiation factor 4 gamma, 1 isoform 1nuclear cap binding protein subunit 1, 80kDaeIF4GI interacts with CBP80-Pubmed
BINDeukaryotic translation initiation factor 4 gamma, 2 isoform 1nuclear cap binding protein subunit 1, 80kDaeIF4GII interacts with CBP80. This interaction was modeled on a demonstrated interaction between human eIF4GII and monkey CBP80.-Pubmed
HPRDHeterogenous nuclear ribonucleoprotein Fnuclear cap binding protein subunit 1, 80kDa--Pubmed
HPRDheterogeneous nuclear ribonucleoprotein FCBP80--Pubmed
HPRDheterogeneous nuclear ribonucleoprotein H1nuclear cap binding protein subunit 1, 80kDa--Pubmed

Recent Publications on NCBP1:

Pubmed Logo
Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery.
BACKGROUND: Treatment of cells with the anti-cancer drug 5-fluorouracil...
23rd August, 2006
Institute of Pathology, Section for Molecular Chemoresistance, Mol Cancer. 2006 May 18;5:20.
DOI Direct Link
Representational difference analysis of cDNA identifies novel genes expressed following preconditioning of the heart.
Preconditioning of the myocardium rapidly induces a number of...
13th December, 2005
Trafford Centre for Graduate Medical Education and Research, University of Exp Mol Med. 2005 Aug 31;37(4):311-22.

NCBP1 results (if any) from reagent suppliers

Google CSE Logo
CBP80 (H-300) Antibody sc-48803
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, NCBP1, 4686, 9q22.33, NM_002486 ...
http://www.scbt.com/datasheet-48803-cbp80-h-300-antibody.htm...

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Antibody Products - IgG Polyclonal Antibodies - GenWay
18-202-335950, NCBP1 / CBP80 Related Product Names: - NCBP1; CBP80; NCBP - Nuclear cap binding protein subunit 1, 80kDa; N/A, IgG Polyclonal ...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=N...

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A-Z Bethyl Laboratories
Cat IgG-Fc · Cat IgG-heavy and light chain · Cat IgM · Cat Light Chain · Cat Reference Serum · Cat Whole Serum · CBP · CBP80/NCBP1 ...
http://www.bethyl.com/category/PCA_A-Z/Antibody/AAAAAAAABAAG...

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CBP antibody, CREB-binding protein (CBP) Antibody, Mouse ...
NCBP1 / CBP80, IgG. Protein GIPC PDZ domain-containing protein 1, Protein · 1,2- dihydroxy-3-keto-5-methylthiopentene dioxygenase, Protein ...
http://www.genwaybio.com/product_info.php?products_id=60015...

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CBP80 Antibody / CBP80 Antibodies
제품명, 카탈로그 번호, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. CBP80 (N-14) Antibody, sc-19973, goat IgG, N-terminus (h), WB, IF, ELISA, human ...
http://www.scbt.com/ko/table-cbp80.html...

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Site Map Bethyl Laboratories
CBP80/NCBP1 ..... NCBP1/CBP80 ...
http://www.bethyl.com/content/sitemap...

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Abcam antibodies and reagents product map
... Muscleblind-like 1 antibodies (5) · Muscleblind-like 1 proteins and peptides (1) · NCBP1 antibodies (3) · NCBP1 proteins and peptides (2) ...
http://www.abcam.com/index.html?c=250...

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