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ATM
| Symbol: | ATM | | Name(s): | ataxia telangiectasia mutated | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | AT1, ATA, ATC, ATD, ATDC, ATE, DKFZp781A0353, MGC74674, TEL1, TELO1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17928013 |
In a cohort of 70 GC samples, low level of phosphorylated ATM was significantly correlated with poor differentiation, lymph node metastasis and poor 5-year survival (P<0.05). |
| 18264724 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18270339 |
Observational study and meta-analysis of gene-disease association. (HuGE Navigator) |
| 17910737 |
Large genomic mutations within the ATM gene by MLPA, including a duplication of 41 kb from exon 4to 20 afre reported. |
| 18164969 |
ATM variants were detected in about 14% of the lung cancer patients and did not differ significantly from the control subjects. |
| 17932249 |
reconstitution of ATM kinase activity decreases FLIP protein levels and restores Fas sensitivity in Hodgkin lymphoma-derived cells |
| 11165203 |
Observational study of gene-disease association. (HuGE Navigator) |
| 11606401 |
Observational study of genotype prevalence and gene-disease association. (HuGE Navigator) |
| 11849780 |
Observational study of gene-disease association. (HuGE Navigator) |
| 11996792 |
Observational study of gene-disease association. (HuGE Navigator) | →View more information from publications. |
Recent Publications on ATM: |  |
Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells.
Naphthalimides, particularly amonafide and... | 3rd November, 2009
| Division of Anti-tumor Pharmacology, State Key Laboratory of Drug
| Neoplasia. 2009 Nov;11(11):1226-34.
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A common gain of function of p53 cancer mutants in inducing genetic instability.
The critical tumor suppressor p53 is mutated in over half of all human... | 3rd November, 2009
| Section of Molecular Biology, Division of Biological Sciences, University
| Oncogene. 2009 Nov 2.
DOI Direct Link |
WIP1 phosphatase at the crossroads of cancer and aging.
The PP2C family serine/threonine phosphatase WIP1 is characterized by... | 3rd November, 2009
| Institute of Molecular and Cell Biology, Cell Cycle Control and
| Trends Biochem Sci. 2009 Oct 28.
DOI Direct Link |
53BP1 represses mitotic catastrophe in syncytia elicited by the HIV-1 envelope.
p53 binding protein-1 (53BP1) participates in checkpoint signaling during... | 31st October, 2009
| [1] INSERM U848, 39 rue Camille-Desmoulins, F-94805 Villejuif, France [2]
| Cell Death Differ. 2009 Oct 30.
DOI Direct Link |
Dose response and kinetics of foci disappearance following exposure to high- and low-LET ionizing radiation.
Purpose: The effect of different radiation qualities on (i) 53BP1 (p53... | 30th October, 2009
| Radiation Biology, Centre for Cancer Research and Cell Biology, Queen's
| Int J Radiat Biol. 2009 Oct;85(10):872-82.
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→View more research publications. |
Press Releases on ATM:
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| China Nepstar Enters Into Strategic Cooperation Agreement with ATMU to Install More Than 1,000 ATMs in Nepstar Stores |
3rd November, 2009 |
China Nepstar Chain Drugstore Ltd. |
SHENZHEN, China, Nov. 3 /PRNewswire-Asia-FirstCall/ -- China Nepstar Chain
Drugstore Ltd. (NYSE: NPD) ("China Nepstar" or the "Company"), the largest
drugstore chain in
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| Novavax Reports Second Quarter 2009 Financial Results |
7th August, 2009 |
Novavax, Inc. |
-- Achieved a major production milestone in the Pandemic H1N1 influenza
program by manufacturing a cGMP-quality batch of the company's VLP
vaccine candidate against this
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| Clinical Data on Semafore's SF1126, a Vascular Targeted Pan-PI3K/mTOR Inhibitor, to be Presented at the 2009 ASCO Meeting |
19th May, 2009 |
Semafore Pharmaceuticals, Inc. |
INDIANAPOLIS, May 19 /PRNewswire/ -- Semafore Pharmaceuticals, Inc., a privately held cancer drug discovery and development company, today announced that it will be reporting Phase I clinical data
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| Woodward Labs Reports Sales Spike for HandClens(R) Alcohol-Free Hand Sanitizer During Swine Flu Epidemic |
30th April, 2009 |
Woodward Laboratories |
Woodward Labs Offer Special Discounts On HandClens(R) and Gives Schools a Free 'Simple as ABC, Always Be Clean' Instruction Manual on How to Prevent Illness.
ALISO
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| Bio-Optronics Incorporates RxPaying(TM) Patient Stipend Debit Card Feature in Clinical Conductor(TM) Clinical Trial Management System (CTMS) |
21st April, 2009 |
Bio-Optronics, Inc. |
ROCHESTER, N.Y., April 21 /PRNewswire/ -- Bio-Optronics, Inc. will enhance its Clinical Conductor(TM) Clinical Trial Management System with click-through integration to Interspond's RxPaying
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ATM results (if any) from reagent suppliers | 
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